Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Alicia Rubio"'
Autor:
Mattia Zaghi, Fabiana Longo, Luca Massimino, Alicia Rubio, Simone Bido, Pietro Giuseppe Mazzara, Edoardo Bellini, Federica Banfi, Paola Podini, Francesca Maltecca, Alessio Zippo, Vania Broccoli, Alessandro Sessa
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Neurodevelopmental disorders (NDDs) are heterogeneous conditions due to alterations of a variety of molecular mechanisms and cell dysfunctions. SETD5 haploinsufficiency leads to NDDs due to chromatin defects. Epigenetic basis of N
Externí odkaz:
https://doaj.org/article/41a9f2cb20ba4eb3b3a5cb5d759d70b4
Publikováno v:
Latin American Research Review, Vol 58, Pp 90-109 (2023)
Entrepreneurship is considered fundamental to economic development since entrepreneurs generate their own economic benefit and indirectly promote employment, boost innovation, and attract human and financial resources and investment in infrastructure
Externí odkaz:
https://doaj.org/article/81d685ae1bdd46a3bc682d3b4cb8dc84
Autor:
Paolo Santambrogio, Maddalena Ripamonti, Anna Cozzi, Marzia Raimondi, Chiara Cavestro, Ivano Di Meo, Alicia Rubio, Stefano Taverna, Valeria Tiranti, Sonia Levi
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-12 (2022)
Abstract Neurodegeneration associated with defective pantothenate kinase-2 (PKAN) is an early-onset monogenic autosomal-recessive disorder. The hallmark of the disease is the massive accumulation of iron in the globus pallidus brain region of patient
Externí odkaz:
https://doaj.org/article/7980b3f04e944f7d8ac44cb339971253
Autor:
Federica Banfi, Alicia Rubio, Mattia Zaghi, Luca Massimino, Giulia Fagnocchi, Edoardo Bellini, Mirko Luoni, Cinzia Cancellieri, Anna Bagliani, Chiara Di Resta, Camilla Maffezzini, Angelo Ianielli, Maurizio Ferrari, Rocco Piazza, Luca Mologni, Vania Broccoli, Alessandro Sessa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Schinzel-Giedion syndrome (SGS) is a fatal developmental syndrome characterized by severe intellectual and physical deficits due, at least in part, to early neurodegeneration. Here the authors introduce a human SGS model that displays disease-relevan
Externí odkaz:
https://doaj.org/article/9f82d3e4675e4ed291494e6ac2e0dfe7
Publikováno v:
Small Business International Review, Vol 4, Iss 2, Pp 53-66 (2020)
La pandemia actual -COVID19- ha llevado a muchos gobiernos a tomar medidas drásticas en respuesta a la crisis de salud global. Las medidas de bloqueo como respuesta a la crisis han frenado aún más las actividades económicas a nivel mundial. En es
Externí odkaz:
https://doaj.org/article/de214d59acac4a9fb7bc55c69b0d8d76
Autor:
Anna Cozzi, Daniel I. Orellana, Paolo Santambrogio, Alicia Rubio, Cinzia Cancellieri, Serena Giannelli, Maddalena Ripamonti, Stefano Taverna, Giulia Di Lullo, Ermanna Rovida, Maurizio Ferrari, Gian Luca Forni, Chiara Fiorillo, Vania Broccoli, Sonia Levi
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 832-846 (2019)
Summary: Neuroferritinopathy (NF) is a movement disorder caused by alterations in the L-ferritin gene that generate cytosolic free iron. NF is a unique pathophysiological model for determining the direct consequences of cell iron dysregulation. We es
Externí odkaz:
https://doaj.org/article/1a80b9ac5a774715806543d0e61b3993
Publikováno v:
Suma de Negocios, Vol 10, Iss 22, Pp 65-71 (2019)
This paper focuses on the analisys of entrepreneurship and disabled people. It is the main objective to identify the main obstacles to become an entrepreneur, particularly economic, fiscal and organizative barriers. It is used a case study methodolog
Externí odkaz:
https://doaj.org/article/7397652516c7484c828dabf29b4aebc1
Autor:
Angelo Iannielli, Giovanni Stefano Ugolini, Chiara Cordiglieri, Simone Bido, Alicia Rubio, Gaia Colasante, Marco Valtorta, Tommaso Cabassi, Marco Rasponi, Vania Broccoli
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4646-4656.e4 (2019)
Summary: Stem cell-derived neurons are generally obtained in mass cultures that lack both spatial organization and any meaningful connectivity. We implement a microfluidic system for long-term culture of human neurons with patterned projections and s
Externí odkaz:
https://doaj.org/article/6c19f59060884387bf61e15b4feb78ac
Autor:
Rocco Piazza, Vera Magistroni, Sara Redaelli, Mario Mauri, Luca Massimino, Alessandro Sessa, Marco Peronaci, Maciej Lalowski, Rabah Soliymani, Caterina Mezzatesta, Alessandra Pirola, Federica Banfi, Alicia Rubio, Delphine Rea, Fabio Stagno, Emilio Usala, Bruno Martino, Leonardo Campiotti, Michele Merli, Francesco Passamonti, Francesco Onida, Alessandro Morotti, Francesca Pavesi, Marco Bregni, Vania Broccoli, Marc Baumann, Carlo Gambacorti-Passerini
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
SETBP1 variants occur as somatic mutations in several malignancies and as de novo germline mutations in developmental disorders. Here the authors provide evidence that SETBP1 binds to gDNA in AT-rich promoter regions to promote target gene upregulati
Externí odkaz:
https://doaj.org/article/ba93d3f63f634212b28426582bbfc01b
Autor:
Angelo Iannielli, Simone Bido, Lucrezia Folladori, Alice Segnali, Cinzia Cancellieri, Alessandra Maresca, Luca Massimino, Alicia Rubio, Giuseppe Morabito, Leonardo Caporali, Francesca Tagliavini, Olimpia Musumeci, Giuliana Gregato, Erwan Bezard, Valerio Carelli, Valeria Tiranti, Vania Broccoli
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2066-2079 (2018)
Summary: Dysfunctions in mitochondrial dynamics and metabolism are common pathological processes associated with Parkinson’s disease (PD). It was recently shown that an inherited form of PD and dementia is caused by mutations in the OPA1 gene, whic
Externí odkaz:
https://doaj.org/article/e74ec4bf3763430d970714f46ab17f1c