Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alicia Rodriguez-Gabin"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Panobinostat (pano) is an FDA-approved histone deacetylase inhibitor. There is interest in evaluating alternate dosing schedules and novel combinations of pano for the treatment of upper aerodigestive and lung malignancies; thus we evaluated
Externí odkaz:
https://doaj.org/article/8bf6e32804f94f5480e8b18e2a01b3ef
Autor:
Adam Friedman, Kenny Ye, Alicia Rodriguez-Gabin, Joshua Nosanchuk, Joel Friedman, Alan Alfieri, Mahantesh Navanti, Angelo Landriscina, Jamie Rosen, David Schairer, Joy Makdisi, Brandon Adler, Aimee Krausz, Hayley McDaid
Publikováno v:
Precision Nanomedicine, Vol 1, Iss 3 (2018)
The effect of size and release kinetics of doxorubicin-nanoparticles on anti-tumor efficacy was evaluated in a panel of human cancer cell lines, including triple-negative breast cancer (TNBC) cells that frequently demonstrate resistance to doxorubici
Externí odkaz:
https://doaj.org/article/cc184e3e053b4f9b927a14c97314973b
Autor:
June Y Hou, Alicia Rodriguez-Gabin, Leleesha Samaraweera, Rachel Hazan, Gary L Goldberg, Susan Band Horwitz, Hayley M McDaid
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151750 (2016)
Externí odkaz:
https://doaj.org/article/191d07942caa49ad8b0328d48e8538e4
Autor:
June Y Hou, Alicia Rodriguez-Gabin, Leleesha Samaraweera, Rachel Hazan, Gary L Goldberg, Susan Band Horwitz, Hayley M McDaid
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54103 (2013)
While the clinical benefit of MEK inhibitor (MEKi)-based therapy is well established in Raf mutant malignancies, its utility as a suppressor of hyperactive MAPK signaling in the absence of mutated Raf or Ras, is an area of ongoing research. MAPK acti
Externí odkaz:
https://doaj.org/article/e9e92161999f4cda9464fffe33e86bc2
Autor:
Hayley M. McDaid, Nancy R. Zhang, Andrea E. Prota, Alicia Rodriguez-Gabin, Tobias Mühlethaler, Michel O. Steinmetz, Kenny Ye, Amos B. Smith, Boying Guo, Susan Band Horwitz
Publikováno v:
Mol Pharmacol
The natural product (+)-discodermolide (DDM) is a microtubule stabilizing agent and potent inducer of senescence. We refined the structure of DDM and evaluated the activity of novel congeners in triple negative breast and ovarian cancers, malignancie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f91a5c25c2181a1b575a7fd5eba75df
https://doi.org/10.1124/mol.119.117457
https://doi.org/10.1124/mol.119.117457
Autor:
Alan A. Alfieri, Brandon L. Adler, Adam J. Friedman, Aimee Krausz, Angelo Landriscina, Joel M. Friedman, Hayley M. McDaid, Mahantesh S. Navati, Alicia Rodriguez-Gabin, Kenny Ye, David Schairer, Jamie Rosen, Joshua D. Nosanchuk, Joy Makdisi
Publikováno v:
Precision Nanomedicine
Precision nanomedicine
Precision nanomedicine
The effect of size and release kinetics of doxorubicin-nanoparticles on anti-tumor efficacy was evaluated in a panel of human cancer cell lines, including triple-negative breast cancer (TNBC) cells that frequently demonstrate resistance to doxorubici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ff1aec4f87a769de304701f0febf1d
https://doi.org/10.33218/prnano1(3).181029.1
https://doi.org/10.33218/prnano1(3).181029.1
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Panobinostat (pano) is an FDA-approved histone deacetylase inhibitor. There is interest in evaluating alternate dosing schedules and novel combinations of pano for the treatment of upper aerodigestive and lung malignancies; thus we evaluated it in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badc9ac646a1255ca805305f6fd0fc76
https://doi.org/10.1038/s41598-017-01964-1
https://doi.org/10.1038/s41598-017-01964-1
Autor:
Marina Frimer, Gary L. Goldberg, June Y. Hou, Alicia Rodriguez-Gabin, Yanhua Wang, Kelly S. Levano, Susan Band Horwitz
Publikováno v:
Gynecologic oncology. 141(1)
Objective Treatment options are limited for patients with uterine serous carcinoma (USC). Knowledge of USC's somatic mutation landscape is rapidly increasing, but its role in hereditary cancers remains unclear. We aim to evaluate the frequency and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e512e7c460a501e50cadfbe5ab22f561
https://pubmed.ncbi.nlm.nih.gov/27016235
https://pubmed.ncbi.nlm.nih.gov/27016235
Autor:
Guillermina Almazan, J.N. Larocca, Michael Cammer, Alicia Rodriguez-Gabin, Maureen J. Charron
Publikováno v:
Journal of Neuroscience Research. 66:1149-1160
Intracellular membrane trafficking plays an essential role in the biogenesis and maintenance of myelin. Members of the Rab protein family are important components of the systems that regulate intracellular vesicle transport. We examine the function o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda42a1f9228536b3b04c47a166053e6
https://doi.org/10.1002/jnr.1253
https://doi.org/10.1002/jnr.1253
Autor:
R. Burcelin, Maureen J. Charron, Guillermina Almazan, Alicia Rodriguez-Gabin, Jorge N. Larocca
Publikováno v:
Molecular Brain Research. 50:9-15
Vesicle transport plays an important role in the formation of myelin. Transport of proteins, including proteolipid protein and myelin associated glycoprotein, from their site of synthesis in the endoplasmic reticulum in the perikaryon of the oligoden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d55c4cc1f50cbd64aaf13c4925f46a2
https://doi.org/10.1016/s0169-328x(97)00151-4
https://doi.org/10.1016/s0169-328x(97)00151-4