Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alicia P Mizes"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The release of Heat Shock Proteins (HSPs) from aberrant cells can initiate immune responses following engagement of the HSPs with antigen presenting cells (APCs). This is an important mechanism for cancer immunosurveillance and can also be m
Externí odkaz:
https://doaj.org/article/97d4f75192d24757a9d884d4ad3eb92d
Distinct heat shock protein-mediated immune responses are induced by macrophages and dendritic cells
Publikováno v:
The Journal of Immunology. 202:59.10-59.10
Heat shock proteins (HSPs) induce potent immune responses against their chaperoned antigens and thus have potential as cancer immunotherapy. APCs, T cells, and NK cells are all required in HSP-mediated immune responses. NK cells are activated indirec
Publikováno v:
The Journal of Immunology. 200:58.5-58.5
Gp96, an immunogenic Heat Shock Protein, is capable of eliciting potent immune responses against its chaperoned antigens and is being investigated as a potential cancer immunotherapy. Gp96 induces immune responses by activating antigen presenting cel