Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alicia Otero"'
Autor:
Tomás Barrio, Sylvie L. Benestad, Jean-Yves Douet, Alvina Huor, Séverine Lugan, Naïma Aron, Hervé Cassard, Juan Carlos Espinosa, Alicia Otero, Rosa Bolea, Juan María Torres, Olivier Andréoletti
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 12, Pp 2691-2694 (2024)
Chronic wasting disease (CWD) is an emerging disease in Europe. We report an increase in interspecies transmission capacity and zoonotic potential of a moose CWD isolate from Europe after passage in an ovine prion protein–expressing host. Those res
Externí odkaz:
https://doaj.org/article/55e00fa14ecd4a1191c0ace39ac0bdfc
Autor:
Sonia Pérez-Lázaro, Tomás Barrio, Susana B. Bravo, Eloisa Sevilla, Alicia Otero, María del Pilar Chantada-Vázquez, Inmaculada Martín-Burriel, Jesús R. Requena, Juan J. Badiola, Rosa Bolea
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-15 (2024)
Current diagnostic methods for prion diseases only work in late stages of the disease when neurodegeneration is irreversible. Therefore, biomarkers that can detect the disease before the onset of clinical symptoms are necessary. High-throughput disco
Externí odkaz:
https://doaj.org/article/71ad7db0b36348569bd41d035cee86fe
Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie
Autor:
Marina Betancor, Belén Marín, Alicia Otero, Carlos Hedman, Antonio Romero, Tomás Barrio, Eloisa Sevilla, Jean-Yves Douet, Alvina Huor, Juan José Badiola, Olivier Andréoletti, Rosa Bolea
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-7 (2023)
Abstract The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie
Externí odkaz:
https://doaj.org/article/2a677dd837164793b30505a9a15f2807
Autor:
Enric Vidal, Manuel A. Sánchez-Martín, Hasier Eraña, Sonia Pérez Lázaro, Miguel A. Pérez-Castro, Alicia Otero, Jorge M. Charco, Belén Marín, Rafael López-Moreno, Carlos M. Díaz-Domínguez, Mariví Geijo, Montserrat Ordóñez, Guillermo Cantero, Michele di Bari, Nuria L. Lorenzo, Laura Pirisinu, Claudia d’Agostino, Juan María Torres, Vincent Béringue, Glenn Telling, Juan J. Badiola, Martí Pumarola, Rosa Bolea, Romolo Nonno, Jesús R. Requena, Joaquín Castilla
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is d
Externí odkaz:
https://doaj.org/article/ec75bdeb108f452fac8587687f697f39
Autor:
Anthony Ness, Aradhana Jacob, Kelsey Saboraki, Alicia Otero, Danielle Gushue, Diana Martinez Moreno, Melanie de Peña, Xinli Tang, Judd Aiken, Susan Lingle, Debbie McKenzie
Publikováno v:
Prion, Vol 16, Iss 1, Pp 40-57 (2022)
Chronic wasting disease (CWD) is a contagious and fatal transmissible spongiform encephalopathy affecting species of the cervidae family. CWD has an expanding geographic range and complex, poorly understood transmission mechanics. CWD is disproportio
Externí odkaz:
https://doaj.org/article/807683c514d14785ab2e1ec286965244
Autor:
Jenny Lozada Ortiz, Marina Betancor, Sonia Pérez Lázaro, Rosa Bolea, Juan J. Badiola, Alicia Otero
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Chronic accumulation of misfolded proteins such as PrPSc can alter the endoplasmic reticulum homeostasis triggering the unfolded protein response (UPR). In this pathogenic event, the molecular chaperones play an important role. Several reports in hum
Externí odkaz:
https://doaj.org/article/36dbdfa18cf64b08855551c148dff36d
Autor:
Diego Sola, Marina Betancor, Paula A. Marco Lorente, Sonia Pérez Lázaro, Tomás Barrio, Eloisa Sevilla, Belén Marín, Bernardino Moreno, Marta Monzón, Cristina Acín, Rosa Bolea, Juan J. Badiola, Alicia Otero
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1399 (2023)
Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies. This review explores the challenges of scrapie di
Externí odkaz:
https://doaj.org/article/a09a68ca32cc40e7afbfe4f4d56f9e1e
Autor:
Alicia Otero, Tomás Barrio, Hasier Eraña, Jorge M Charco, Marina Betancor, Carlos M Díaz-Domínguez, Belén Marín, Olivier Andréoletti, Juan M Torres, Qingzhong Kong, Juan J Badiola, Rosa Bolea, Joaquín Castilla
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010900 (2022)
The role of the glycosylation status of PrPC in the conversion to its pathological counterpart and on cross-species transmission of prion strains has been widely discussed. Here, we assessed the effect on strain characteristics of bovine spongiform e
Externí odkaz:
https://doaj.org/article/0b9b47e51bab4ad7aecf29df2bd11115
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-13 (2021)
Abstract The spread of chronic wasting disease (CWD) during the last six decades has resulted in cervid populations of North America where CWD has become enzootic. This insidious disease has also been reported in wild and captive cervids from other c
Externí odkaz:
https://doaj.org/article/828a55db30f643ee8d64f9fe9ac2db89
Autor:
Belén Marín, Alicia Otero, Séverine Lugan, Juan Carlos Espinosa, Alba Marín-Moreno, Enric Vidal, Carlos Hedman, Antonio Romero, Martí Pumarola, Juan J. Badiola, Juan María Torres, Olivier Andréoletti, Rosa Bolea
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the inoculation of certain scrapie and chron
Externí odkaz:
https://doaj.org/article/9ccd201f696e4cacb95cf160a870d459