Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alicia N. Minniti"'
Autor:
Alicia N. Minniti, Eryn Fennelly, Brenna Duffy, Natausha Davis, Elizabeth Chatburn, Nibaldo C. Inestrosa, Rebecca E. Kohn
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal, p 1 (2012)
Oxidative stress is considered a significant contributor to cellular damage, which may accumulate and result in cellular and organism senescence and death. Oxidative stress and damage have been correlated with a number of central nervous system (CNS)
Externí odkaz:
https://doaj.org/article/a9e786aaa45448668dd443e727083c99
Autor:
Pablo Cabrera, Pedro Jara-Guajardo, María Paz Oyarzún, Nicole Parra-Muñoz, Aldo Campos, Mónica Soler, Alejandra Álvarez, Francisco Morales-Zavala, Eyleen Araya, Alicia N. Minniti, Rebeca Aldunate, Marcelo J. Kogan
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
The β-amyloid (Aβ) peptide is one of the key etiological agents in Alzheimer's disease (AD). The in vivo detection of Aβ species is challenging in all stages of the illness. Currently, the development of fluorescent probes allows the detection of
Autor:
Alicia N. Minniti, Hector Arriagada, Francisco Morales-Zavala, Eyleen Araya, Macarena Sánchez-Navarro, Ana Riveros, Carolina Velasco, Marcelo J. Kogan, Ximena Rojas-Silva, Ernest Giralt, Natalia Hassan, Rebeca Aldunate, Katherine Rodriguez, Luis Muñoz, Rodrigo A. Vásquez, Alejandra R. Alvarez
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:2341-2350
The properties of nanometric materials make nanotechnology a promising platform for tackling problems of contemporary medicine. In this work, gold nanorods were synthetized and stabilized with polyethylene glycols and modified with two kinds of pepti
Autor:
Alicia N. Minniti, Hector Arriagada, Rebeca Aldunate, Soledad Zúñiga, Iván E. Alfaro, Marcela Bravo-Zehnder
Publikováno v:
Aging Cell
The insulin‐IGF‐1/DAF‐2 pathway has a central role in the determination of aging and longevity in Caenorhabditis elegans and other organisms. In this paper, we measured neuronal insulin secretion (using INS‐22::Venus) during C. elegans lifesp
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1864(6 Pt)
Oxidative stress affects the survival and function of neurons. Hence, they have a complex and highly regulated machinery to handle oxidative changes. The dysregulation of this antioxidant machinery is associated with a wide range of neurodegenerative
Autor:
Alicia N. Minniti, Rebecca Kohn, Iván Neira, Daniela L. Rebolledo, Rebeca Aldunate, Nibaldo C. Inestrosa
Publikováno v:
Journal of Neuroscience. 31:10149-10158
Alzheimer's disease and inclusion body myositis (IBM) are disorders frequently found in the elderly and characterized by the presence of amyloid-β peptide (Aβ) aggregates. We used Caenorhabditis elegans that express Aβ in muscle cells as a model o
Autor:
Rebeca Aldunate, Luis Vasquez, Romina Cataldo, Federico Leighton, Patricio E. Mujica, Nibaldo C. Inestrosa, Alicia N. Minniti, Carla Trigo
Publikováno v:
AGING CELL
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Summary The methionine sulfoxide reductase system has been implicated in aging and protection against oxidative stress. This conserved system reverses the oxidation of methionine residues within proteins. We analyzed one of the components of this sys
Autor:
Nibaldo C. Inestrosa, Francisca Ramos, Macarena S. Arrázola, Marcela Bravo-Zehnder, Rebeca Aldunate, Alicia N. Minniti
Publikováno v:
Antioxidants & Redox Signaling
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Aims: To examine the role of the enzyme methionine sulfoxide reductase A-1 (MSRA-1) in amyloid-β peptide (Aβ)-peptide aggregation and toxicity in vivo, using a Caenorhabditis elegans model of the human amyloidogenic disease inclusion body myositis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0427c9cb8511b6628d7a4a30b66404
Publikováno v:
Genetics. 152:209-220
During spermiogenesis, Caenorhabditis elegans spermatids activate and mature into crawling spermatozoa without synthesizing new proteins. Mutations in the spe-12 gene block spermatid activation, rendering normally self-fertile hermaphrodites sterile.
Publikováno v:
BIOMETALS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Sporadic-inclusion body myositis (s-IBM) is the most common skeletal muscle disorder to afflict the elderly, and is clinically characterized by skeletal muscle degeneration. Its progressive course leads to muscle weakness and wasting, resulting in se