Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alicia Martinez-Lopez"'
Autor:
Corey H. Yu, Akash Bhattacharya, Mirjana Persaud, Alexander B. Taylor, Zhonghua Wang, Angel Bulnes-Ramos, Joella Xu, Anastasia Selyutina, Alicia Martinez-Lopez, Kristin Cano, Borries Demeler, Baek Kim, Stephen C. Hardies, Felipe Diaz-Griffero, Dmitri N. Ivanov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
SAMHD1 catalyses the dephosphorylation of deoxynucleotide triphosphates (dNTPs) and has antiretroviral activity. Here, the authors present the crystal structures of SAMHD1-oligonucleotide complexes, which reveal that the allosteric binding sites of S
Externí odkaz:
https://doaj.org/article/235030ae21f844b790931e36a84dca12
Autor:
Alicia Martinez-Lopez, Mirjana Persaud, Maritza Puray Chavez, Hongjie Zhang, Lijun Rong, Shufeng Liu, Tony T. Wang, Stefan G. Sarafianos, Felipe Diaz-Griffero
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 269-283 (2019)
Background: Flaviviruses such as Zika cause sporadic pandemic outbreaks worldwide. There is an urgent need for anti-Zika virus (ZIKV) drugs to prevent mother-to-child transmission of ZIKV, new infections in high-risk populations, and the infection of
Externí odkaz:
https://doaj.org/article/c501f0f7912b4b21a318e5ad574195a1
Autor:
Anastasia Selyutina, Mirjana Persaud, Lacy M. Simons, Angel Bulnes-Ramos, Cindy Buffone, Alicia Martinez-Lopez, Viviana Scoca, Francesca Di Nunzio, Joseph Hiatt, Alexander Marson, Nevan J. Krogan, Judd F. Hultquist, Felipe Diaz-Griffero
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3766-3777.e6 (2020)
Summary: Disruption of cyclophilin A (CypA)-capsid interactions affects HIV-1 replication in human lymphocytes. To understand this mechanism, we utilize human Jurkat cells, peripheral blood mononuclear cells (PBMCs), and CD4+ T cells. Our results sho
Externí odkaz:
https://doaj.org/article/16232fc48689471cb4b57d165d4967e7
Autor:
Alicia Martinez-Lopez, Maria C. Millan-Linares, Noelia M. Rodriguez-Martin, Francisco Millan, Sergio Montserrat-de la Paz
Publikováno v:
Journal of Functional Foods, Vol 65, Iss , Pp 103735- (2020)
Amaranthus caudatus L. (Amaranthaceae), commonly known as kiwicha, is considered as one of the few multipurpose pseudocereal crops which supply higher nutritional seeds in huge quantities. A. caudatus is rich source of proteins, β-carotene, vitamins
Externí odkaz:
https://doaj.org/article/7ed87149850a47a9bf3cc74cc9f8cc41
Autor:
Sergio Montserrat-de la Paz, Alicia Martinez-Lopez, Alvaro Villanueva-Lazo, Justo Pedroche, Francisco Millan, Maria C. Millan-Linares
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 645 (2021)
Kiwicha (Amaranthus caudatus) is considered one of the few multipurpose pseudocereals for its potential use not only as a source of nutrients and fiber but also for its bioactive compounds. In recent years, antioxidant peptides are commonly used as f
Externí odkaz:
https://doaj.org/article/2bf5871895104610b12a13aa77a38d60
Autor:
Amparo Estepa, Antonio Figueras, Beatriz Novoa, Pablo Garcia-Valtanen, Pablo Balseiro, Jose Antonio Encinar, Regla Maria Medina-Gali, Alicia Martinez-Lopez
Publikováno v:
Marine Drugs, Vol 11, Iss 7, Pp 2328-2346 (2013)
Myticin C (Myt C) is a highly variable host-defense peptide (HDP) associated to the immune response in the mediterranean mussel (Mytilus galloprovincialis), which has shown to be active across species due to its strong antiviral activity against a fi
Externí odkaz:
https://doaj.org/article/e7c2da8f968a43f6ae89a618c40116de
Autor:
Alicia Martinez-Lopez, Pablo García-Valtanen, María Del Mar Ortega-Villaizan, Verónica Chico, Regla María Medina-Gali, Luis Perez, Julio Coll, Amparo Estepa
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77426 (2013)
The route of administration of DNA vaccines can play a key role in the magnitude and quality of the immune response triggered after their administration. DNA vaccines containing the gene of the membrane-anchored glycoprotein (gpG) of the fish rhabdov
Externí odkaz:
https://doaj.org/article/afd26362499b4c7ca460e47c59eb224e
Autor:
Alicia Martinez-Lopez, Fernando Rivero-Pino, Alvaro Villanueva, Rocio Toscano, Elena Grao-Cruces, Elvira Marquez-Paradas, Maria E. Martin, Sergio Montserrat-de la Paz, Maria C. Millan-Linares
4 Figuras.-- 2 Tablas
The increase in the world population along with new policies aimed at a more sustainable world has led to the need of searching for new food sources, which are environmentally friendly, implying healthy and nutritious diets
The increase in the world population along with new policies aimed at a more sustainable world has led to the need of searching for new food sources, which are environmentally friendly, implying healthy and nutritious diets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c0b941f30439a9c7c2022b217eb434
http://hdl.handle.net/10261/283172
http://hdl.handle.net/10261/283172
Autor:
Alicia, Martinez-Lopez, Fernando, Rivero-Pino, Alvaro, Villanueva, Rocio, Toscano, Elena, Grao-Cruces, Elvira, Marquez-Paradas, Maria E, Martin, Sergio, Montserrat-de la Paz, Maria C, Millan-Linares
Publikováno v:
Foodfunction. 13(22)
The increase in the world population along with new policies aimed at a more sustainable world has led to the need of searching for new food sources, which are environmentally friendly, implying healthy and nutritious diets. This study explored the b
Autor:
Akash Bhattacharya, Corey H. Yu, Kristin E. Cano, Anastasia Selyutina, Angel Bulnes-Ramos, Baek Kim, Alicia Martinez-Lopez, Zhonghua Wang, Joella Xu, Stephen C. Hardies, Dmitri N. Ivanov, Mirjana Persaud, Alexander B. Taylor, Felipe Diaz-Griffero, Borries Demeler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
SAMHD1 impedes infection of myeloid cells and resting T lymphocytes by retroviruses, and the enzymatic activity of the protein—dephosphorylation of deoxynucleotide triphosphates (dNTPs)—implicates enzymatic dNTP depletion in innate antiviral immu