Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alicia M. Waters"'
Autor:
Adele P. Williams, Evan F. Garner, Alicia M. Waters, Laura L. Stafman, Jamie M. Aye, Hooper Markert, Jerry E. Stewart, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 84-95 (2019)
High-risk neuroblastoma continues to carry a poor prognosis. Nearly 50% of these tumors relapse following extensive treatment regimens. Protein phosphatase 2A (PP2A), a tumor suppressor, has been shown to be downregulated in many human cancers via mu
Externí odkaz:
https://doaj.org/article/e301bf95fdb34b2097d8ae0defd2aedc
Autor:
M. R. Chambers, R. Timothy Bentley, David K. Crossman, Jeremy B. Foote, Jey W. Koehler, James M. Markert, Nidal B. Omar, Simon R. Platt, D. Mitchell Self, Andy Shores, Donald C. Sorjonen, Alicia M. Waters, Amy B. Yanke, G. Yancey Gillespie
Publikováno v:
Frontiers in Surgery, Vol 7 (2020)
As the most common and deadly of primary brain tumors, malignant gliomas have earned their place within one of the most multifaceted and heavily-funded realms of medical research. Numerous avenues of pre-clinical investigation continue to provide val
Externí odkaz:
https://doaj.org/article/add041996e8b42f1a30a67e8817fde3d
Autor:
Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Gregory K. Friedman, Jennifer M. Coleman, James M. Markert, G. Yancey Gillespie, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 9, Iss 5, Pp 419-430 (2016)
Rhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common sarcoma of childhood. Despite multidrug chemotherapy regimens, surgical intervention, and radiation treatment, outcomes remain poor, especially in advanced disease, and nov
Externí odkaz:
https://doaj.org/article/6e4edd8f93794346a21f1fb0ce62b1fe
Autor:
Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Elizabeth Mroczek-Musulman, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 9, Iss 4, Pp 263-273 (2016)
Despite the tremendous advances in the treatment of childhood solid tumors, rhabdomyosarcoma (RMS) continues to provide a therapeutic challenge. Children with metastatic or relapsed disease have a disease-free survival rate under 30%. Focal adhesion
Externí odkaz:
https://doaj.org/article/b5bd3aaff2064b53b27bfa1b1025c3f5
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Figure S1 / S2. UAB30 activated caspase 3. Figure S3. UAB30 increased nestin protein. Figure S4 / S5. UAB30 decreased neuroblastoma cellular proliferation. Figure S6 / S7. UAB30 did not alter expression or phosphorylation of ERK1/2 or AKT. Figure S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eec685733995105952fb1722e984eab
https://doi.org/10.1158/1535-7163.22501552.v1
https://doi.org/10.1158/1535-7163.22501552.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Neuroblastoma remains a common cause of pediatric cancer deaths, especially for children who present with advanced stage or recurrent disease. Currently, retinoic acid therapy is used as maintenance treatment to induce differentiation and reduce tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348dc350f3894592ab83c27de40a958f
https://doi.org/10.1158/1535-7163.c.6536827.v1
https://doi.org/10.1158/1535-7163.c.6536827.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Representative photomicrographs of G401 cells stained for total RXR (red) and nucleus (DAPI, blue) showed increased overlap after UAB30 treatment (merged, bottom right panel) indicating increased RXR staining in the nucleus following UAB30 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90e1c915e3151ca1804658caf4c5644
https://doi.org/10.1158/1535-7163.22508349.v1
https://doi.org/10.1158/1535-7163.22508349.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Cellular proliferation was measured with trypan blue exclusion. Cell lines were treated with UAB30 at 0 or 10 μM for 24 hrs. Cells were stained with trypan blue and counted with a hemacytometer. A The total number of cells decreased in all 3 cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b50f9f9e20fbcc372b8f6168f23d0b
https://doi.org/10.1158/1535-7163.22508343
https://doi.org/10.1158/1535-7163.22508343
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Legends for the supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e40f3fc502b667958d8a6d55dcc9159
https://doi.org/10.1158/1535-7163.22508352
https://doi.org/10.1158/1535-7163.22508352
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
The effects of UAB30 upon the expression and phosphorylation of kinases involved in cellular survival and apoptosis were evaluated with immunoblotting. Cells were treated with UAB30 (10 µM) and whole cell lysates were examined with immunoblotting fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b17dfc51951778bfab70e3980655b1
https://doi.org/10.1158/1535-7163.22508331
https://doi.org/10.1158/1535-7163.22508331