Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alicia M. Jones"'
A Novel Bayesian General Medical Diagnostic Assistant Achieves Superior Accuracy With Sparse History
Autor:
Alicia M. Jones, Daniel R. Jones
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
Online AI symptom checkers and diagnostic assistants (DAs) have tremendous potential to reduce misdiagnosis and cost, while increasing the quality, convenience, and availability of healthcare, but only if they can perform with high accuracy. We intro
Externí odkaz:
https://doaj.org/article/b0e87110c63a4f6abc03c7767a067eeb
Autor:
Alicia M, Jones, Daniel R, Jones
Publikováno v:
Frontiers in artificial intelligence. 5
Online AI symptom checkers and diagnostic assistants (DAs) have tremendous potential to reduce misdiagnosis and cost, while increasing the quality, convenience, and availability of healthcare, but only if they can perform with high accuracy. We intro
Publikováno v:
Protein Eng Des Sel
Adenylate kinase (AK) orthologs with a range of thermostabilities were subjected to random circular permutation, and deep mutational scanning was used to evaluate where new protein termini were nondisruptive to activity. The fraction of circularly pe
Autor:
Emily E. Thomas, Laura Segatori, Yimeng Zeng, Alicia M. Jones, Jonathan J. Silberg, Barbara Nassif
Publikováno v:
ACS Synthetic Biology. 7:2126-2138
Monitoring the aggregation of proteins within the cellular environment is key to investigating the molecular mechanisms underlying the formation of off-pathway protein assemblies associated with the development of disease and testing therapeutic stra
Publikováno v:
Learning Disabilities: A Multidisciplinary Journal. 21:31-45
Processing Strengths and Weaknesses (PSW) models have been proposed as a method for identifying specific learning disabilities. Three PSW models were examined for their ability to predict expert identified specific learning disabilities cases. The Du
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1498
Rearrangements that alter the order of a protein's sequence are used in the lab to study protein folding, improve activity, and build molecular switches. One of the simplest ways to rearrange a protein sequence is through random circular permutation,
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964703
Rearrangements that alter the order of a protein's sequence are used in the lab to study protein folding, improve activity, and build molecular switches. One of the simplest ways to rearrange a protein sequence is through random circular permutation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483423e574a2482ea081eef919982634
https://doi.org/10.1007/978-1-4939-6472-7_19
https://doi.org/10.1007/978-1-4939-6472-7_19
Autor:
Shirley Liu, Manan M. Mehta, Emily E. Thomas, Joshua T. Atkinson, Jonathan J. Silberg, Alicia M. Jones, Thomas H. Segall-Shapiro
Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement in which native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7ba4fe09fe85e077a2b948593cbb95
https://europepmc.org/articles/PMC5122316/
https://europepmc.org/articles/PMC5122316/
Publikováno v:
Nucleic Acids Research
Deep mutational scanning has been used to create high-resolution DNA sequence maps that illustrate the functional consequences of large numbers of point mutations. However, this approach has not yet been applied to libraries of genes created by rando
Publikováno v:
Langmuir. 33:4090-4090
The photothermal efficacy of near-infrared gold nanoparticles (NP), nanoshells, and nanorods was studied under pulsed high-energy optical excitation in plasmonic nanobubble (PNB) mode as a function of the wavelength and duration of the excitation las