Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alicia M. Cole"'
Autor:
Owen J. Sansom, Peter Sicinski, Alan R. Clarke, Hans Clevers, Vanesa Muncan, Gijs R. Van den Brink, Dimitris Athineos, Rachel A. Ridgway, Karen R. Reed, Kevin Myant, Alicia M. Cole
Supplementary Methods from Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735d25fe316279327d4adfb599c78cc3
https://doi.org/10.1158/0008-5472.22383912
https://doi.org/10.1158/0008-5472.22383912
Autor:
Owen J. Sansom, Peter Sicinski, Alan R. Clarke, Hans Clevers, Vanesa Muncan, Gijs R. Van den Brink, Dimitris Athineos, Rachel A. Ridgway, Karen R. Reed, Kevin Myant, Alicia M. Cole
Supplementary Figure Legends 1-4 from Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe75938d0117370b401673f133c12c
https://doi.org/10.1158/0008-5472.22383918.v1
https://doi.org/10.1158/0008-5472.22383918.v1
Autor:
Owen J. Sansom, Peter Sicinski, Alan R. Clarke, Hans Clevers, Vanesa Muncan, Gijs R. Van den Brink, Dimitris Athineos, Rachel A. Ridgway, Karen R. Reed, Kevin Myant, Alicia M. Cole
Supplementary Figures 1-4 from Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7011bad2a42c78ba28a510c200a9307e
https://doi.org/10.1158/0008-5472.22383915.v1
https://doi.org/10.1158/0008-5472.22383915.v1
Autor:
Owen J. Sansom, Peter Sicinski, Alan R. Clarke, Hans Clevers, Vanesa Muncan, Gijs R. Van den Brink, Dimitris Athineos, Rachel A. Ridgway, Karen R. Reed, Kevin Myant, Alicia M. Cole
Inactivation of the Apc gene is recognized as the key early event in the development of sporadic colorectal cancer (CRC), where its loss leads to constitutive activation of β-catenin/T-cell factor 4 signaling and hence transcription of Wnt target ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc3150ad61337c941637349d21009be
https://doi.org/10.1158/0008-5472.c.6500706
https://doi.org/10.1158/0008-5472.c.6500706
Autor:
Miriam R, Fernandes, Poonam, Aggarwal, Raquel G F, Costa, Alicia M, Cole, Giorgio, Trinchieri
Publikováno v:
Nature reviews. Cancer. 22(12)
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of cancer therapy, most notably immunotherapy and its immune-related adverse effects. The poor response to immunotherapy in patients treated with antibiotics suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdf2c0a74e4e337a2343b3480cf4e970
https://pubmed.ncbi.nlm.nih.gov/36253536
https://pubmed.ncbi.nlm.nih.gov/36253536
Autor:
Richelle DeBlasio, Marie Vétizou, Jonathan H. Badger, Giorgio Trinchieri, Stephanie Prescott, Hassane M. Zarour, Miriam R. Fernandes, John A. McCulloch, Bochra Zidi, Richard R. Rodrigues, Amir A. Borhani, Yana G. Najjar, Amy Rose, John M. Kirkwood, Shuowen Zhang, Hong Wang, Carmine Menna, Quanquan Ding, Scarlett J. Ernst, Amiran K. Dzutsev, Alicia M. Cole, Joe Marc Chauvin, Robert M. Morrison, Ornella Pagliano, Diwakar Davar, Andrey Morgun, Ascharya K. Balaji, Raquel Galvão Figueredo Costa, Howard M. Dubner, Ivan Vujkovic-Cvijin, Yasmine Belkaid, Marc Schwartz
Publikováno v:
Science. 371:595-602
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al. report first-in-human clinical trials to test whether fecal microbiota transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cda59c60ac26ba7edf8744836a549a
https://doi.org/10.1126/science.abf3363
https://doi.org/10.1126/science.abf3363
Publikováno v:
Cancer Research. 82:1687-1687
Single-cell level investigations such as DNA and RNA sequencing, protein analyses, and phenotypic studies require an input sample with a high rate of viability (>90%). If too many dead cells are present in the input, degraded proteins and ambient DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abaf984c7e40f548219f2a924abfeeca
https://doi.org/10.1158/1538-7445.am2022-1687
https://doi.org/10.1158/1538-7445.am2022-1687
Autor:
Alicia M. Cole, Rolando H. Rolandelli, Daniel Hakakian, Louis T. DiFazio, Terrence Curran, Andrew G. Del Rosario, Dorian A. Bogdanovski, Zoltan H. Nemeth
Publikováno v:
The American Surgeon. 84:407-410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a8ddc75d7fe17e0ad653f2c1b88d9d
https://doi.org/10.1177/000313481808400925
https://doi.org/10.1177/000313481808400925
Autor:
Hassane M. Zarour, Richelle DeBlasio, Marc Schwartz, Stephanie Prescott, Ivan Vujkovic-Cvijin, Amy Rose, Marie Vétizou, Scarlett J. Ernst, Jonathan H. Badger, Howard M. Dubner, Hong Wang, Yasmine Belkaid, John M. Kirkwood, Ascharya K. Balaji, Amiran Dzutsev, Diwakar Davar, Yana G. Najjar, Quanquan Ding, Raquel Galvão Figueredo Costa, Joe-Marc Chauvin, Shuowen Zhang, Carmine Menna, Amir A. Borhani, Giorgio Trinchieri, John A. McCulloch, Bochra Zidi, Richard R. Rodrigues, Ornella Pagliano, Miriam R. Fernandes, Andrey Morgun, Robert M. Morrison, Alicia M. Cole
Publikováno v:
Cancer Research. 81:LB062-LB062
Background: Monoclonal antibodies (mAb) targeting the programmed cell death protein 1 (PD-1) receptor provide durable long-term benefit in a subset of patients (pts) with advanced melanoma with response rates of 35-42% and 4-year progression-free sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0300891d510a8394935f382c6e4c76a9
https://doi.org/10.1158/1538-7445.am2021-lb062
https://doi.org/10.1158/1538-7445.am2021-lb062
Autor:
Ignacio Moreno de Alborán, Hans Clevers, Owen J. Sansom, Vanesa Muncan, Harry Begthel, Alicia M. Cole, Alan Richard Clarke, Leon Tertoolen, Elena Sancho, Alex Gregorieff, Toby J. Phesse
Publikováno v:
Molecular and Cellular Biology, 38(24). American Society for Microbiology
Inhibition of the mutationally activated Wnt cascade in colorectal cancer cell lines induces a rapid G1 arrest and subsequent differentiation. This arrest can be overcome by maintaining expression of a single Tcf4 target gene, the proto-oncogene c-My
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807b95ad3d0da825bbb9f23619588a70
https://hdl.handle.net/20.500.11755/0e0c0d2e-4fce-4b9a-b288-1619735bb4f7
https://hdl.handle.net/20.500.11755/0e0c0d2e-4fce-4b9a-b288-1619735bb4f7