Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alicia M, Winquist"'
Autor:
Evan Y. Snyder, Angela R. Ozburn, Colleen A. McClung, Mariah A. Hildebrand, George C. Tseng, Jeffrey Oliver-Smith, Matthew B Jarpe, Alicia M. Winquist, Hui Zhang, Wei Zong, Puja K. Parekh, Darius Becker-Krail, Zhiguang Huo, Ethan Fitzgerald, Rachel N. Arey, Xiyu Zhu, Lauren M. DePoy, Andrew Crain, Kyle D. Ketchesin, Brian T. D. Tobe, Xiangning Xue, Ryan W. Logan
Publikováno v:
Molecular psychiatry
Valproate (VPA) has been used in the treatment of bipolar disorder since the 1990s. However, the therapeutic targets of VPA have remained elusive. Here we employ a preclinical model to identify the therapeutic targets of VPA. We find compounds that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3c998801c8fc52a7971dd952089690
http://europepmc.org/articles/PMC8141541
http://europepmc.org/articles/PMC8141541
Autor:
Evan Y. Snyder, Jinxia Wang, Alicia M. Winquist, Irene Tseu, Sharareh Shojaie, Daochun Luo, Neal H. Nathan, Martin Post, Sandra L Leibel
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Surfactant protein B (SFTPB) deficiency is a fatal disease affecting newborn infants. Surfactant is produced by alveolar type II cells which can be differentiated in vitro from patient specific induced pluripotent stem cell (iPSC)-derived lung organo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48919c1634ea0231a5cddfd858858d06
http://link.springer.com/article/10.1038/s41598-019-49696-8
http://link.springer.com/article/10.1038/s41598-019-49696-8
Publikováno v:
Journal of Visualized Experiments.
Human lung development and disease has been difficult to study due to the lack of biologically relevant in vitro model systems. Human induced pluripotent stem cells (hiPSCs) can be differentiated stepwise into 3D multicellular lung organoids, made of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abdcde660b85792dd8e9eefdc165be1
https://doi.org/10.3791/62456-v
https://doi.org/10.3791/62456-v
Publikováno v:
Current Protocols in Stem Cell Biology
The normal development of the pulmonary system is critical to transitioning from placental‐dependent fetal life to alveolar‐dependent newborn life. Human lung development and disease have been difficult to study due to the lack of an in vitro mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6c98b2a46b16b8660c1323d6c2404f
https://pubmed.ncbi.nlm.nih.gov/32640120
https://pubmed.ncbi.nlm.nih.gov/32640120
Autor:
Brian T. D. Tobe, Alicia M. Winquist, Laurence M. Brill, Gustavo J. Gutierrez, Andrew Crain, Stuart A. Lipton, Junjie Hou, Jennifer Choy, Kutbuddin S. Doctor, Maria Talantova, Evan Y. Snyder, Esther La Monaca, Dieter A. Wolf, Xiayu Huang, David Horn, Ilyas Singec
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Stem cell reports, vol 7, iss 3
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Stem cell reports, vol 7, iss 3
Summary Controlled differentiation of human embryonic stem cells (hESCs) can be utilized for precise analysis of cell type identities during early development. We established a highly efficient neural induction strategy and an improved analytical pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f648220803f9d96faf220f4af68fd67c
http://europepmc.org/articles/PMC5032292
http://europepmc.org/articles/PMC5032292
Autor:
Cameron D, Pernia, Neal H, Nathan, Brian T D, Tobe, Alicia M, Winquist, Richard L, Sidman, Yoshio, Goshima, Evan Y, Snyder
Publikováno v:
Results and problems in cell differentiation. 66
The pathogenesis of bipolar disorder (BPD) is unknown. Using human-induced pluripotent stem cells (hiPSCs) to unravel pathological mechanisms in polygenic diseases is challenging, with few successful studies to date. However, hiPSCs from BPD patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca4f33033e708328d55b2188ef5e237e
https://pubmed.ncbi.nlm.nih.gov/30209664
https://pubmed.ncbi.nlm.nih.gov/30209664
Autor:
Brian T. D. Tobe, Alicia M. Winquist, Neal H. Nathan, Cameron D. Pernia, Evan Y. Snyder, Richard L. Sidman, Yoshio Goshima
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783319934846
The pathogenesis of bipolar disorder (BPD) is unknown. Using human-induced pluripotent stem cells (hiPSCs) to unravel pathological mechanisms in polygenic diseases is challenging, with few successful studies to date. However, hiPSCs from BPD patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e366b3627a449da00d24a5ab9a0c22e7
https://doi.org/10.1007/978-3-319-93485-3_12
https://doi.org/10.1007/978-3-319-93485-3_12
Autor:
Fumio Nakamura, Husseini K. Manji, Namrata D. Udeshi, Hagop S. Akiskal, Jeffrey H. Price, Nikolaos Venizelos, Wen-Ning Zhao, Cordulla Duerr, Ryan W. Logan, Jeffrey S. Nye, Jasmin Lalonde, Steven D. Sheridan, Joseph T. Coyle, Toshio Ohshima, Yoshio Goshima, Michael McCarthy, Shelley Halpain, Barbara Calabrese, Joshua G. Hunsberger, Martin Alda, Yuuka Inoue, Gustavo J. Gutierrez, Stephen J. Haggarty, Brian T. D. Tobe, Cameron D. Pernia, Richard L. Sidman, Moyuka Wada, Hiroko Makihara, Laurence M. Brill, Glenn T. Konopaske, Yang Liu, De-Maw M. Chuang, Ranor C. B. Basa, Alicia M. Winquist, Yang D. Teng, Michelle M. Sidor, Steven A. Carr, Colleen A. McClung, Guy A. Rouleau, Katsuhiko Mikoshiba, Evan Y. Snyder, Laurel Dorsett, Lina Mastrangelo, Guang Chen, Jianxue Li, Haruko Nakamura, Andrew Crain, Philipp Mertins, Michael G. Brandel, Dongmei Wu, Naoya Yamashita
Publikováno v:
Publikationer från Örebro universitet.
The molecular pathogenesis of bipolar disorder (BPD) is poorly understood. Using human-induced pluripotent stem cells (hiPSCs) to unravel such mechanisms in polygenic diseases is generally challenging. However, hiPSCs from BPD patients responsive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af943d65b2b76fb0f4b555e7351a2c67
http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57888
http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57888
Autor:
Alicia M. Winquist, Jin Woo Lee, Evan Y. Snyder, Ilyas Singec, Shaochen Chen, Pranav Soman, Kenneth S. Vecchio, Brian T. D. Tobe
Publikováno v:
Biomedical Microdevices. 14:829-838
Access to unlimited numbers of live human neurons derived from stem cells offers unique opportunities for in vitro modeling of neural development, disease-related cellular phenotypes, and drug testing and discovery. However, to develop informative ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d3558c33ee6a83908820108aa7b48f
https://doi.org/10.1007/s10544-012-9662-7
https://doi.org/10.1007/s10544-012-9662-7
Autor:
Walter D. Niles, Paul A. Jain, Lina Mastrangelo, Brian T. D. Tobe, Shreyasi Das, Alicia M. Winquist, Evan Y. Snyder
Treatment for neurological diseases or trauma remains the last frontier in modern medicine because there is no effective way to repair the central nervous system (CNS) and restore function. In this chapter, we discuss neural stem cells (NSCs) as an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70890e972b6d7bcb72cc2c06cee8d147
https://doi.org/10.1016/b978-0-12-410396-2.00029-3
https://doi.org/10.1016/b978-0-12-410396-2.00029-3