Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Alicia M, Bolt"'
Autor:
Kartika Wardhani, Sydnee Yazzie, Charlotte McVeigh, Onamma Edeh, Martha Grimes, Quiteria Jacquez, Connor Dixson, Edward Barr, Rui Liu, Alicia M. Bolt, Changjian Feng, Katherine E. Zychowski
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Rural regions of the western United States have experienced a noticeable surge in both the frequency and severity of acute wildfire events, which brings significant challenges to both public safety and environmental conservation e
Externí odkaz:
https://doaj.org/article/f6fcd3dbc87b44e19de66eafa8db5e9e
Aging, longevity, and the role of environmental stressors: a focus on wildfire smoke and air quality
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Aging is a complex biological process involving multiple interacting mechanisms and is being increasingly linked to environmental exposures such as wildfire smoke. In this review, we detail the hallmarks of aging, emphasizing the role of telomere att
Externí odkaz:
https://doaj.org/article/7c01c5a95a2143a092280cd40fe405fc
Autor:
Jennifer H. Toyoda, Julieta Martino, Rachel M. Speer, Idoia Meaza, Haiyan Lu, Aggie R. Williams, Alicia M. Bolt, Joseph Calvin Kouokam, Abou El-Makarim Aboueissa, John Pierce Wise
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 256 (2023)
Hexavalent chromium [Cr(VI)] is a known human lung carcinogen with widespread exposure in environmental and occupational settings. Despite well-known cancer risks, the molecular mechanisms of Cr(VI)-induced carcinogenesis are not well understood, but
Externí odkaz:
https://doaj.org/article/6c7e5b487d494b228b5bd0aefbdfc0f7
Autor:
Guanghua Wan, Sebastian Medina, Haikun Zhang, Rong Pan, Xixi Zhou, Alicia M. Bolt, Li Luo, Scott W. Burchiel, Ke Jian Liu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Arsenic exposure poses numerous threats to human health. Our previous work in mice has shown that arsenic causes anemia by inhibiting erythropoiesis. However, the impacts of arsenic exposure on human erythropoiesis remain largely unclear. We
Externí odkaz:
https://doaj.org/article/e38830cfb8fd47e49acfa75a5b9e5b86
Autor:
Sebastian Medina, Haikun Zhang, Laura V. Santos-Medina, Zachary A. Yee, Kaitlin J. Martin, Guanghua Wan, Alicia M. Bolt, Xixi Zhou, Miroslav Stýblo, Ke Jian Liu
Publikováno v:
Water, Vol 15, Iss 3, p 448 (2023)
Chronic arsenic exposures via the consumption of contaminated drinking water are clearly associated with many deleterious health outcomes, including anemia. Following exposure, trivalent inorganic arsenic (AsIII) is methylated through a series of ars
Externí odkaz:
https://doaj.org/article/1797031524214ca48b0ec40f367bb054
Publikováno v:
Methods and Protocols, Vol 5, Iss 3, p 46 (2022)
Interstitial fluid (ISF) bathes the cells and tissues and is in constant exchange with blood. As an exchange medium for waste, nutrients, exosomes, and signaling molecules, ISF is recognized as a plentiful source of biomolecules. Many basic and pre-c
Externí odkaz:
https://doaj.org/article/c6f4928ab2eb4863b66489e53a5aaa29
Autor:
Kiran Makhani, Chris Chiavatti, Luis Fernando Negro Silva, Maryse Lemaire, Alicia M Bolt, Nicolas De Jay, Braeden Giles, Ayse Nazli Zengin, Claudia L Kleinman, Koren K Mann
Publikováno v:
Toxicological Sciences. 192:83-96
Arsenic exposure is correlated with atherosclerosis in epidemiological studies and in animal models. We have previously shown that arsenic exposure enhanced the atherosclerotic plaque size, increased the plaque lipid content, and decreased the plaque
Autor:
Ryuhjin Ahn, Valérie Sabourin, Alicia M. Bolt, Steven Hébert, Stephanie Totten, Nicolas De Jay, Maria Carolina Festa, Yoon Kow Young, Young Kyuen Im, Tony Pawson, Antonis E. Koromilas, William J. Muller, Koren K. Mann, Claudia L. Kleinman, Josie Ursini-Siegel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Tyrosine kinase signalling in cancer cells promotes immune evasion. Here, the authors show that tyrosine kinases engage scaffold protein Shc1 to promote immunosuppression in breast cancer by simultaneously activating STAT3 immunosuppressive signals a
Externí odkaz:
https://doaj.org/article/4564af3090224e7180bdbbc6e315baaa
Autor:
Kiran, Makhani, Chris, Chiavatti, Luis Fernando, Negro Silva, Maryse, Lemaire, Alicia M, Bolt, Nicolas, de Jay, Braeden, Giles, Ayse Nazli, Zengin, Claudia L, Kleinman, Koren K, Mann
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology.
Arsenic exposure is correlated with atherosclerosis in epidemiological studies and in animal models. We have previously shown that arsenic exposure enhanced atherosclerotic plaque size, increased plaque lipid content and decreased plaque smooth muscl
Autor:
Alicia M. Bolt
Publikováno v:
Advances in Pharmacology ISBN: 9780323997751
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d73248b113692555b554c76c4976b58
https://doi.org/10.1016/bs.apha.2022.10.004
https://doi.org/10.1016/bs.apha.2022.10.004