Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alicia L. S. Thompson"'
Autor:
Jenny L. Wiley, John W. Huffman, Alicia L. S. Thompson, Dana E. Selley, Seon A. Hepburn, Billy R. Martin, Nataliya Lyutenko
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:7809-7815
Δ 8 -Tetrahydrocannabinol ( 26 ), 3-(1′,1′-dimethylbutyl)- ( 12 ), 3-(1′,1′-dimethylpentyl)- ( 13 ), 3-(1′,1′-dimethylhexyl)- ( 14 ) and 3-(1′,1′-dimethylheptyl)-Δ 8 -tetrahydrocannabinol ( 15 ) have been converted into the correspo
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:322-335
A series of 1-deoxy analogs of CP-47,497 (8 and 13, n = 0 to 7) and 1-deoxy analogs of CP-55,940 (9, n = 0 to 7) have been synthesized and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. Although the majority of these
Publikováno v:
Synthesis. 2005:547-550
Mild, novel procedures have been developed for the syntheses of aryl halides from the corresponding phenols in modest to good yields via boronate ester intermediates.
Autor:
Simon M. Bushell, Ming-Jung Wu, George Hynd, Dow P. Hurst, Billy R. Martin, Dana E. Selley, Gulay Zengin, Jianzhong Lu, Patricia H. Reggio, Cindy Tartal, John W. Huffman, Jenny L. Wiley, Kristen Bushell, Alicia L. S. Thompson, Michael P. Cassidy
Publikováno v:
Bioorganicmedicinal chemistry. 13(1)
In an effort to improve indole-based CB(2) cannabinoid receptor ligands and also to develop SAR for both the CB(1) and CB(2) receptors, 47 indole derivatives were prepared and their CB(1) and CB(2) receptor affinities were determined. The indole deri