Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.

Autor: Alicia L Carlson, Joji Fujisaki, Juwell Wu, Judith M Runnels, Raphaël Turcotte, Joel A Spencer, Cristina Lo Celso, David T Scadden, Terry B Strom, Charles P Lin

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e69257 (2013)

We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after light exposure and does not rea

Externí odkaz: https://doaj.org/article/a13444ed0e004c2ebba7a256bb3b4ef6

Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design

Autor: Farid Sari-Sarraf, Gillis R. Otten, Timothy Pepini, Thomas Carsillo, Carlo Iavarone, Jeffrey B. Ulmer, Dong Yu, Alicia L. Carlson, Giulietta Maruggi, Jason C. Debasitis, Katrin Ramsauer, Anne-Marie Pulichino, Andrew Geall

Publikováno v: The Journal of Immunology. 198:4012-4024

RNA-based vaccines have recently emerged as a promising alternative to the use of DNA-based and viral vector vaccines, in part because of the potential to simplify how vaccines are made and facilitate a rapid response to newly emerging infections. SA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bb56454b7ca4b588da1373c4fa5482
https://doi.org/10.4049/jimmunol.1601877

Confocal Microscopy and Molecular-Specific Optical Contrast Agents for the Detection of Oral Neoplasia

Autor: Adel K. El-Naggar, Rebecca Richards-Kortum, Alicia L. Carlson, Michelle D. Williams, Ann M. Gillenwater

Publikováno v: Technology in Cancer Research & Treatment. 6:361-374

Using current clinical diagnostic techniques, it is difficult to visualize tumor morphology and architecture at the cellular level, which is necessary for diagnostic localization of pathologic lesions. Optical imaging techniques have the potential to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbb104ad0e955e5c2073978e49d529e
https://doi.org/10.1177/153303460700600501

Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation

Autor: Guiling Zhao, Alicia L. Carlson, Giovanna Andreola, Megan Sykes, Charles P. Lin, Hao Wei Li, Steven Shao

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 195(3)

Inflammation in the priming host environment has critical effects on the graft-versus-host (GVH) responses mediated by naive donor T cells. However, it is unclear how a quiescent or inflammatory environment impacts the activity of GVH-reactive primed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134b9540db6cf90cf38c4d9983827375
https://pubmed.ncbi.nlm.nih.gov/26085679

Myocardial infarction accelerates atherosclerosis

Autor: Michael A. Moskowitz, Filip K. Swirski, Mikael J. Pittet, Matthias Nahrendorf, Rostic Gorbatov, Brian Thompson, Marc S. Sabatine, Timo Heidt, Anja M. van der Laan, Michael T. Waring, Gabriel Courties, Hugo A. Katus, David A. Morrow, Yoshiko Iwamoto, Jagdish Butany, Martin Etzrodt, Hans W.M. Niessen, Claudio Vinegoni, Jan J. Piek, Peter Libby, Partha Dutta, Ying Wei, Sabina A. Murphy, Felix Lasitschka, Alicia L. Carlson, Barry B. Rubin, Clinton S. Robbins, Charles P. Lin, Florian Leuschner, Peter Waterman, Adam T. Chicoine, Ralph Weissleder, James R. Stone, Maulik D. Majmudar

Publikováno v: Nature, 487(7407), 325-329. Nature Publishing Group
Dutta, P, Courties, G, Wei, Y, Leuschner, F, Gorbatov, R, Robbins, C S, Iwamoto, Y, Thompson, B, Carlson, A L, Heidt, T, Majmudar, M D, Lasitschka, F, Etzrodt, M, Waterman, P, Waring, M T, Chicoine, A T, van der Laan, A M, Niessen, H W M, Piek, J J, Rubin, B B, Butany, J, Stone, J R, Katus, H A, Murphy, S A, Morrow, D A, Sabatine, M S, Vinegoni, C, Moskowitz, M A, Pittet, M J, Libby, P, Lin, C P, Swirski, F K, Weissleder, R & Nahrendorf, M 2012, ' Myocardial infarction accelerates atherosclerosis ', Nature, vol. 487, no. 7407, pp. 325-329 . https://doi.org/10.1038/nature11260
Nature

During progression of atherosclerosis, myeloid cells destabilize lipid-rich plaques in the arterial wall and cause their rupture, thus triggering myocardial infarction and stroke. Survivors of acute coronary syndromes have a high risk of recurrent ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28aecb6e9570d6d09b630aa1fe4f971
https://pure.amc.nl/en/publications/myocardial-infarction-accelerates-atherosclerosis(bb86550a-23e2-4457-a4f6-eebb9006420e).html