Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alicia J. Taylor"'
Autor:
Justine M. Whitworth, Alicia J. Taylor, Sophie Caroline Williams, Alan Findlay Haughan, Philip J. Gilbert, Duncan R. Hannah, George M. Buckley, Natasha Davies, Rachael Profit, William R. Pitt, Hazel Joan Dyke, Caroline A. Hunt, Marianna D. Richard, Nicholas C. Ray, Andrew Sharpe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:751-754
The development of a series of novel quinazolinethiones and quinazolinediones as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro inhibitory values for IMPDH II and in vitro inhibitory value for PBMC pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836874af7b31b9fc5782f3b758df37a8
https://doi.org/10.1016/j.bmcl.2004.11.015
https://doi.org/10.1016/j.bmcl.2004.11.015
Autor:
Andrew J. Ratcliffe, Michael J. Madigan, William R. Pitt, Justine M. Whitworth, Duncan R. Hannah, Philip J. Gilbert, Marianna D. Richard, Alicia J. Taylor, Elizabeth J. Frost, Andrew Sharpe, George M. Buckley, Sophie Caroline Williams, Nicholas C. Ray, Trevor Morgan, Alan Findlay Haughan, Helen L. Birch, Hazel Joan Dyke, Natasha Davies
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(23)
The synthesis and biological activity of a novel series of 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones are described. Some of these compounds were found to be potent inhibitors of inosine 5'-monophosphate dehydrogenase type II (IMPDH II)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ee7e970dddfb4b40069bfc750253f5
https://pubmed.ncbi.nlm.nih.gov/16202581
https://pubmed.ncbi.nlm.nih.gov/16202581