Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Alicia Gómez-Barrio"'
Autor:
Jhony Anacleto-Santos, Elisa Vega-Ávila, Leticia Pacheco, Manuel Lacueva-Arnedo, Alicia Gómez-Barrio, Alexandra Ibáñez-Escribano, Teresa de Jesús López-Pérez, Brenda Casarrubias-Tabarez, Fernando Calzada, Perla Yolanda López-Camacho, Norma Rivera-Fernández
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 624 (2024)
Pleopeltis crassinervata is a fern documented in ethnobotanical records for its use in Mexican traditional medicine to treat gastric disorders and mouth ulcers. Consequently, conducting biological and pharmacological assays is crucial to validate the
Externí odkaz:
https://doaj.org/article/3482b06586264f0b80609fcf08205121
Autor:
Alexandra Ibáñez-Escribano, Cristina Fonseca-Berzal, Mónica Martínez-Montiel, Manuel Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín-Pérez, José Antonio Escario, Penélope Merino-Montiel, Sara Montiel-Smith, Alicia Gómez-Barrio, Óscar López, José G. Fernández-Bolaños
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 781-791 (2022)
Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evalu
Externí odkaz:
https://doaj.org/article/2e3a62e95f4841cdadefb7f108d1beea
Autor:
Ana L. Legarda-Ceballos, Esther del Olmo, Julio López-Abán, Ricardo Escarcena, Luis A. Bustos, Cristina Fonseca-Berzal, Alicia Gómez-Barrio, Juan C. Dib, Arturo San Feliciano, Antonio Muro
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 11554-11568 (2015)
Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0–6.6 times) than the reference compound nifurtimox. From them, th
Externí odkaz:
https://doaj.org/article/6dc151a5ea3e464e9db0720ab371802d
Autor:
Consuelo Giménez-Pardo, Maria Mercedes Martínez-Grueiro, Alicia Gómez-Barrio, Filomena Rodríguez-Caabeiro
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 99, Iss 2, Pp 223-226 (2004)
Cholinesterase and acid phosphatase (AP), but not alkaline phosphatase activities, were detected in cytosolic and membrane-bound fractions of ivermectin resistant and susceptible Haemonchus contortus infective-stage larvae. Some differences in acetyl
Externí odkaz:
https://doaj.org/article/3145e4d3071741f18d0f95cf6df16947
Autor:
Ana Le-Senne, Susana Muelas-Serrano, Carlos Fernández-Portillo, José Antonio Escario, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 8, Pp 1101-1105 (2002)
Clone CL B5 of Trypanosoma cruzi is a beta-galactosidase expressing organism that was genetically transfected to be used for in vitro pharmacological screening. Biological parameters were determined, evaluating growth kinetics of epimastigotes, metac
Externí odkaz:
https://doaj.org/article/caa3962b946545baa7f292ce71ad995d
Autor:
Alicia Gómez-Barrio, Juan J Nogal-Ruiz, David Montero-Pereira, Ester Rodríguez-Gallego, Esperanza Romero-Fernández, José A Escario
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 6, Pp 893-896 (2002)
Eighteen clinical isolates of Trichomonas vaginalis were obtained from women who attended health centers of the Goverment of Madrid. A total of 1,848 vaginal specimens recovered during the gynaecological examination were seeded in culture tubes conta
Externí odkaz:
https://doaj.org/article/9b06ad8ce47644858e74fc5534d969f6
Autor:
Susana Muelas-Serrano, Ana Le-Senne, Carlos Fernández-Portillo, Juan José Nogal, Carmen Ochoa, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 4, Pp 553-557 (2002)
Nitroarylidenemalononitriles and their cyanoacetamide derivatives with remarkable anti-epimastigote properties, were synthesized attempting to obtain new 3,5-diamino-4-(5'-nitroarylidene)-4H-thiadiazine 1,1-dioxide derivatives, which in previous repo
Externí odkaz:
https://doaj.org/article/0ae5da67da4f43f78c11c8f57d93e43b
Autor:
Susana Muelas, Margarita Suárez, Rolando Pérez, Hortensia Rodríguez, Carmen Ochoa, José Antonio Escario, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 2, Pp 269-272 (2002)
Cytotoxicity assays of 24 new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives were performed. The 17 compounds with higher anti-epimastigote activity and lower cytotoxicity were, thereafter, screened against amastigote of Trypan
Externí odkaz:
https://doaj.org/article/f2499a187a30463e940085fb729c6de0
Autor:
Cristina Fonseca-Berzal, Cristiane França da Silva, Marcos Meuser Batista, Francisca Hildemagna Guedes-da-Silva, Mariane Vasconcelos, Kelly C. Demarque, José A. Escario, Vicente J. Arán, Maria de Nazaré C. Soeiro, Alicia Gómez-Barrio
Publikováno v:
Proceedings, Vol 1, Iss 6, p 655 (2017)
Benznidazole and nifurtimox, the currently available drugs for the specific treatment of Chagas disease, show limited effectiveness and high toxicity that prompt the identification of therapeutic alternatives. [...]
Externí odkaz:
https://doaj.org/article/c81a0dfbbdf74a4084bf5ddef2f4bddb
Autor:
Alexandra Ibáñez-Escribano, Leyre Pernaute Lau, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, Jose Antonio Escario, Michael A. Zeligs
Publikováno v:
Proceedings, Vol 1, Iss 6, p 645 (2017)
New, safe, well tolerated, and versatile anti-trichomonal agents for oral and topical use are needed to combat spreading resistance of Trichomonas vaginalis to metronidazole (MTZ). [...]
Externí odkaz:
https://doaj.org/article/5fa70984e779414299cc7d67a749b245