Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Alicia Gómez Barrio"'
Autor:
Alexandra Ibáñez Escribano, Alfredo Meneses Marcel, Yanetsy Machado Tugores, Juan José Nogal Ruiz, Vicente J Arán Redó, José Antonio Escario García-Trevijano, Alicia Gómez Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 5, Pp 637-643 (2012)
A fluorimetric microassay that uses a redox dye to determine the viability of the flagellate Trichomonas vaginalis has been optimised to provide a more sensitive method to evaluate potential trichomonacidal compounds. Resazurin has been used in recen
Externí odkaz:
https://doaj.org/article/3d54a80d7ae7461d8654683bf4d01c96
Autor:
Jhony Anacleto-Santos, Elisa Vega-Ávila, Leticia Pacheco, Manuel Lacueva-Arnedo, Alicia Gómez-Barrio, Alexandra Ibáñez-Escribano, Teresa de Jesús López-Pérez, Brenda Casarrubias-Tabarez, Fernando Calzada, Perla Yolanda López-Camacho, Norma Rivera-Fernández
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 624 (2024)
Pleopeltis crassinervata is a fern documented in ethnobotanical records for its use in Mexican traditional medicine to treat gastric disorders and mouth ulcers. Consequently, conducting biological and pharmacological assays is crucial to validate the
Externí odkaz:
https://doaj.org/article/3482b06586264f0b80609fcf08205121
Autor:
Ana L. Legarda-Ceballos, Esther del Olmo, Julio López-Abán, Ricardo Escarcena, Luis A. Bustos, Cristina Fonseca-Berzal, Alicia Gómez-Barrio, Juan C. Dib, Arturo San Feliciano, Antonio Muro
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 11554-11568 (2015)
Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0–6.6 times) than the reference compound nifurtimox. From them, th
Externí odkaz:
https://doaj.org/article/6dc151a5ea3e464e9db0720ab371802d
Autor:
Denise da Gama Jaen Batista, Alicia Gómez-Barrio, José Antonio Escario, Vicente J. Arán, Cristiane França da Silva, Maria de Nazaré Correia Soeiro, Raiza Brandão Peres, Gabriel Melo de Oliveira, A. S. G. Nefertiti, José Cumella, Marcos Meuser Batista, Cristina Fonseca-Berzal
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
In previous studies, we have identified several families of 5-nitroindazole derivatives as promising antichagasic prototypes. Among them, 1-(2-aminoethyl)-2-benzyl-5-nitro-1,2-dihydro-3H-indazol-3-one, (hydrochloride) and 1-(2-acetoxyethyl)-2-benzyl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1118d1fa4a53698738b806b85c7610
https://doi.org/10.1017/s0031182020000955
https://doi.org/10.1017/s0031182020000955
Autor:
Alexandra, Ibáñez-Escribano, Cristina, Fonseca-Berzal, Mónica, Martínez-Montiel, Manuel, Álvarez-Márquez, María, Gómez-Núñez, Manuel, Lacueva-Arnedo, Teresa, Espinosa-Buitrago, Tania, Martín-Pérez, José Antonio, Escario, Penélope, Merino-Montiel, Sara, Montiel-Smith, Alicia, Gómez-Barrio, Óscar, López, José G, Fernández-Bolaños
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 37(1)
Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5365d1f717a494155d721b02823e239
https://pubmed.ncbi.nlm.nih.gov/35193444
https://pubmed.ncbi.nlm.nih.gov/35193444
Autor:
Cristina Fonseca-Berzal, Alexandra Ibáñez-Escribano, Sonia de Castro, José A. Escario, Alicia Gómez-Barrio, Vicente J. Arán
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
In this study, a new series of eleven 5-nitroindazole derivatives (10−20) and a related 6-nitroquinazoline (21) was synthesized and tested in vitro against different forms of the kinetoplastid parasite Trypanosoma cruzi, etiological agent of Chagas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650b37a24444c49249e9fce2a19ac0b8
http://hdl.handle.net/10261/279866
http://hdl.handle.net/10261/279866
Autor:
Alexandra Ibáñez-Escribano, Cristina Fonseca-Berzal, Mónica Martínez-Montiel, Manuel Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín-Pérez, José Antonio Escario, Penélope Merino-Montiel, Sara Montiel-Smith, Alicia Gómez-Barrio, Óscar López, José G. Fernández-Bolaños
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
instname
Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7358e6c073ba63a39c99331422c3c84
Autor:
Alexandra Ibáñez-Escribano, Nerea Vela, Felipe Reviriego, Cristina Fonseca-Berzal, Vicente J. Arán, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, José Antonio Escario
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
E-Prints Complutense. Archivo Institucional de la UCM
instname
E-Prints Complutense. Archivo Institucional de la UCM
A series of 11 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles (2–12) has been prepared starting from 1-benzyl-5-nitroindazol-3-ol 13, and evaluated against sensitive and resistant isolates of the sexually transmitted protozoan Trichomonas vaginalis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3001b7853b50b016b3da7f2e64b24d
https://eprints.ucm.es/id/eprint/70434/
https://eprints.ucm.es/id/eprint/70434/
Autor:
Cristina, Fonseca-Berzal, Cristiane França, da Silva, Denise da Gama Jaen, Batista, Gabriel Melo, de Oliveira, José, Cumella, Marcos Meuser, Batista, Raiza Brandão, Peres, Aline, Silva da Gama Nefertiti, José A, Escario, Alicia, Gómez-Barrio, Vicente J, Arán, Maria de Nazaré Correia, Soeiro
Publikováno v:
Parasitology
In previous studies, we have identified several families of 5-nitroindazole derivatives as promising antichagasic prototypes. Among them, 1-(2-aminoethyl)-2-benzyl-5-nitro-1,2-dihydro-3H-indazol-3-one, (hydrochloride) and 1-(2-acetoxyethyl)-2-benzyl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::befa5e3a346fc682c74fc468fe7e61fe
https://pubmed.ncbi.nlm.nih.gov/32530391
https://pubmed.ncbi.nlm.nih.gov/32530391
Publikováno v:
Parasitology Research. 117:3367-3380
One of the main problems of Chagas disease (CD), the parasitic infection caused by Trypanosoma cruzi, is the lack of a completely satisfactory treatment, which is currently based on two old nitroheterocyclic drugs (i.e., nifurtimox and benznidazole)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158ab5a7794c5773de30830a3cc41ba8
https://doi.org/10.1007/s00436-018-6084-3
https://doi.org/10.1007/s00436-018-6084-3