The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.

Autor: Tiziana Ginex, Clara Marco-Marín, Miłosz Wieczór, Carlos P Mata, James Krieger, Paula Ruiz-Rodriguez, Maria Luisa López-Redondo, Clara Francés-Gómez, Roberto Melero, Carlos Óscar Sánchez-Sorzano, Marta Martínez, Nadine Gougeard, Alicia Forcada-Nadal, Sara Zamora-Caballero, Roberto Gozalbo-Rovira, Carla Sanz-Frasquet, Rocío Arranz, Jeronimo Bravo, Vicente Rubio, Alberto Marina, IBV-Covid19-Pipeline, Ron Geller, Iñaki Comas, Carmen Gil, Mireia Coscolla, Modesto Orozco, José Luis Llácer, Jose-Maria Carazo

Publikováno v: PLoS Pathogens, Vol 18, Iss 7, p e1010631 (2022)

The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation has since reappeared in the Delta subvariant AY.4.2, raising questions about its specific e

Externí odkaz: https://doaj.org/article/2ac3186a08434f9d9f6e2286ac7350ff

PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network

Autor: José I. Labella, Raquel Cantos, Javier Espinosa, Alicia Forcada-Nadal, Vicente Rubio, Asunción Contreras

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

Synechococcus elongatus PCC 7942 is a paradigmatic model organism for nitrogen regulation in cyanobacteria. Expression of genes involved in nitrogen assimilation is positively regulated by the 2-oxoglutarate receptor and global transcriptional regula

Externí odkaz: https://doaj.org/article/aae18c5f396247318bfdd8d6d65e8faf

Insight into vitamin B6 -dependent epilepsy due to PLPBP (previously PROSC) missense mutations

Autor: Vicente Rubio, Lorena Tremiño, Alicia Forcada-Nadal

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

12 páginas, 3 figuras, 2 tablas. "This is the pre-peer reviewed version of the following article: Hum Mutat. 2018 Jul;39(7):1002-1013, which has been published in final form at http://dx.doi.org/10.1002/humu.23540. This article may be used for non-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafec33503afbd82430a863d9dba3e51
http://hdl.handle.net/10261/171158

PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network

Autor: Vicente Rubio, Raquel Cantos, Asunción Contreras, Javier Espinosa, Jose I. Labella, Alicia Forcada-Nadal

Publikováno v: RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)

16 Pages, 7 Figures, 2 Tables. The Supplementary Material for this article can be found online at: http://journal.frontiersin.org/article/10.3389/fmicb.2017.01244/full#supplementary-material
Synechococcus elongatus PCC 7942 is a paradigmatic mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500dfe74a7cf43bf2c8656fa1d05caa3

Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B6 -dependent epilepsy

Autor: Alicia Forcada-Nadal, Vicente Rubio, Asunción Contreras, Lorena Tremiño

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)

12 páginas, 3 figuras
The Synechococcus elongatus COG0325 gene pipY functionally interacts with the nitrogen regulatory gene pipX. As a first step toward a molecular understanding of such interactions, we characterized PipY. This 221-residue pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b0c6cbbde7b90321e0bcfb110d7a6f
http://hdl.handle.net/10261/156906