Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Alicia Domínguez-Martín"'
Publikováno v:
Crystals, Vol 13, Iss 4, p 570 (2023)
Multicomponent pharmaceutical solids is a hot topic that brings together the knowledge of crystal engineering and the need to achieve novel and effective drugs at lower costs for the pharmaceutical industry [...]
Externí odkaz:
https://doaj.org/article/5ca2539295e74f29a5937887e18b2af4
Autor:
Francisco Javier Acebedo-Martínez, Carolina Alarcón-Payer, Cristóbal Verdugo-Escamilla, Jesús Martín, Antonio Frontera, Alicia Domínguez-Martín, Jaime Gómez-Morales, Duane Choquesillo-Lazarte
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 370 (2023)
Pharmaceutical multicomponent solids have proved to efficiently modulate the physicochemical properties of active pharmaceutical ingredients. In this context, polyphenols are interesting coformers for designing pharmaceutical cocrystals due to their
Externí odkaz:
https://doaj.org/article/f3ec4c7c0fae4ba9906577c090ad56c3
Autor:
Francisco Javier Acebedo-Martínez, Alicia Domínguez-Martín, Carolina Alarcón-Payer, Alejandro Sevillano-Páez, Cristóbal Verdugo-Escamilla, Josefa María González-Pérez, Fernando Martínez-Checa, Duane Choquesillo-Lazarte
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3305 (2023)
Drug–drug salts are a kind of pharmaceutical multicomponent solid in which the two co-existing components are active pharmaceutical ingredients (APIs) in their ionized forms. This novel approach has attracted great interest in the pharmaceutical in
Externí odkaz:
https://doaj.org/article/8b02080b4ed448889d0c3d7cd5d1a2e8
Autor:
Francisco Javier Acebedo-Martínez, Alicia Domínguez-Martín, Carolina Alarcón-Payer, Carolina Garcés-Bastida, Cristóbal Verdugo-Escamilla, Jaime Gómez-Morales, Duane Choquesillo-Lazarte
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 449 (2023)
According to the World Health Organization, more than 422 million people worldwide have diabetes. The most common oral treatment for type 2 diabetes is the drug metformin (MTF), which is usually formulated as a hydrochloride to achieve higher water s
Externí odkaz:
https://doaj.org/article/b724b0cb817b4059a7744bdbcde90d20
Autor:
Cristóbal Verdugo-Escamilla, Carolina Alarcón-Payer, Francisco Javier Acebedo-Martínez, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte
Publikováno v:
Crystals, Vol 12, Iss 12, p 1748 (2022)
Crystal engineering and, more specifically, the development of multicomponent materials has become an effective technique to rationally modify important physicochemical properties of solids, such as solubility and thermal stability. In this work, in
Externí odkaz:
https://doaj.org/article/475aca7cba59462692d1784395ccc326
Autor:
Francisco Javier Acebedo-Martínez, Carolina Alarcón-Payer, Helena María Barrales-Ruiz, Juan Niclós-Gutiérrez, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte
Publikováno v:
Crystals, Vol 12, Iss 8, p 1038 (2022)
Multicomponent pharmaceutical materials offer new opportunities to address drug physicochemical issues and to obtain improved drug formulation, especially on oral administration drugs. This work reports three new multicomponent pharmaceutical crystal
Externí odkaz:
https://doaj.org/article/3a24b49b4f3f4dd18117a4bfbaef7503
Autor:
Cristóbal Verdugo-Escamilla, Carolina Alarcón-Payer, Francisco Javier Acebedo-Martínez, Raquel Fernández-Penas, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte
Publikováno v:
Crystals, Vol 12, Iss 6, p 798 (2022)
In this investigation, three new crystal forms of lidocaine, and another three of lidocaine hydrochloride with hydroquinone, resorcinol, and pyrogallol were synthetised. All the new forms were characterised using multiple techniques, PXRD, SC-XRD, DS
Externí odkaz:
https://doaj.org/article/beee7a3c08a9497690da2d7e673ea82e
Autor:
Francisco Javier Acebedo-Martínez, Carolina Alarcón-Payer, Antonio Frontera, Rafael Barbas, Rafel Prohens, Milena Di Crisci, Alicia Domínguez-Martín, Jaime Gómez-Morales, Duane Choquesillo-Lazarte
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2140 (2021)
Any time the pharmaceutical industry develops a new drug, potential polymorphic events must be thoroughly described, because in a crystalline pharmaceutical solid, different arrangements of the same active pharmaceutical ingredient can yield to very
Externí odkaz:
https://doaj.org/article/89dbc99e9187492d9c72e36752169efa
Autor:
Francisco Javier Acebedo-Martínez, Carolina Alarcón-Payer, Lucía Rodríguez-Domingo, Alicia Domínguez-Martín, Jaime Gómez-Morales, Duane Choquesillo-Lazarte
Publikováno v:
Crystals, Vol 11, Iss 11, p 1339 (2021)
The design of drug–drug multicomponent pharmaceutical solids is one the latest drug development approaches in the pharmaceutical industry. Its purpose is to modulate the physicochemical properties of active pharmaceutical ingredients (APIs), most o
Externí odkaz:
https://doaj.org/article/2dbd11e4465a4bdf88ead726879edd45
Autor:
Inmaculada Velo-Gala, Miquel Barceló-Oliver, Diego M. Gil, Josefa M. González-Pérez, Alfonso Castiñeiras, Alicia Domínguez-Martín
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 244 (2021)
The synthetic nucleoside acyclovir is considered an outstanding model of the natural nucleoside guanosine. With the purpose of deepening on the influence and nature of non-covalent interactions regarding molecular recognition patterns, three novel Cu
Externí odkaz:
https://doaj.org/article/32b04e0572254be99852d043330ce88b