Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice.

Autor: Amanda Schoner, Christina Tyrrell, Melinda Wu, Jill M Gelow, Alicia A Hayes, Jonathan R Lindner, Kent L Thornburg, Wohaib Hasan

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142940 (2015)

An experimental model of endocardial thrombosis has not been developed and endocardial endothelial dysfunction in heart failure (HF) is understudied. We sought to determine whether disruption of the endothelial anti-coagulant activated protein C (APC

Externí odkaz: https://doaj.org/article/8c464a136cd44d02b111af35d38ed3c7

A new system for comparative functional genomics of Saccharomyces yeasts

Autor: Sarah J. Pfau, Peter A. Combs, Carmen Young, J. Scott Breunig, Yufei Liu, Sandhya Sinha, Maitreya J. Dunham, Rosa M. Mendoza, Max V. Staller, Aaron Hoisos, Richa Gawande, Konrad J. Karczewski, Julia Liu, Jie Yuan, Erin C. Bush, Namita Bisaria, Christian Millian, Hugo Arellano, Daniel Gadala-Maria, Samuel Grossberg, Evgeni M. Frenkel, William Rounds, Christopher A. Crutchfield, Alicia P. Hayes, David S. Glass, Walter Chen, Joy Agee, Chris DeSevo, Matthew S. Rich, Jenny Hsi, Philip Stern, Trevor Martin, Sanford J. Silverman, Sandeep Raj, Mina L Kojima, Christopher D. Doucette, Matthew Salesi, Sachi Inukai, Samuel S. Freeman, Olga G. Troyanskaya, Anita Gupta, David Botstein, Juan R. Alvarez-Dominguez, Xiaobo Ke, Cameron Myhrvold, Peter Fellowes, Manuel Llinás, Rajani Sharma, John J. Clore, Maxwell Weidmann, Amy A. Caudy, Coleen T. Murphy, Patrick H. Bradley, Christina Hansen, Yue Jia, David A. Cappel, Joseph Rokicki, Olukunle O. Demuren, Samuel Leachman, Daniel R. Barrett, Hanlin Tang, Anna Liebowitz, Yuanfang Guan, Cynthia Bauerle, Jose Mena, Michael Salazar, Cara Singer, Sharon Weeks, Ashley R. Wolf, Megan N. McClean, Emily J. Capra, Latanya Hammonds-Odie, Daniel S. Lieber, Yu-Han Huang Hsu

Publikováno v: Genetics

Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More difficult, however, is experimental testing of the inferences about gene function that can be drawn from comparative sequence analysis alone. We present a genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a8e75cea2960982b0bbf0c60bfe6de
https://pubmed.ncbi.nlm.nih.gov/23852385

Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice

Autor: Jill M. Gelow, Kent L. Thornburg, Alicia A. Hayes, Melinda Wu, Wohaib Hasan, Amanda Schoner, Christina Tyrrell, Jonathan R. Lindner

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 11, p e0142940 (2015)

Objective An experimental model of endocardial thrombosis has not been developed and endocardial endothelial dysfunction in heart failure (HF) is understudied. We sought to determine whether disruption of the endothelial anti-coagulant activated prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9405f56377d1632051f3e5940cfc5660
https://doi.org/10.1371/journal.pone.0142940

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features.

Autor: Rao S; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. Srinivasa.rao@nds.ox.ac.uk.; Botnar Research Centre, Windmill Road, Oxford, OX3 7LD, UK. Srinivasa.rao@nds.ox.ac.uk., Verrill C; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Cerundolo L; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Alham NK; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Kaya Z; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., O'Hanlon M; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Hayes A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Lambert A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., James M; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Tullis IDC; Department of Oncology, University of Oxford, Oxford, UK., Niederer J; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Lovell S; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Omer A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Lopez F; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Leslie T; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Buffa F; Department of Oncology, University of Oxford, Oxford, UK., Bryant RJ; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Lamb AD; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Vojnovic B; Department of Oncology, University of Oxford, Oxford, UK., Wedge DC; Manchester Cancer Research Centre, University of Manchester, Manchester, UK., Mills IG; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Woodcock DJ; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

Publikováno v: Genome medicine [Genome Med] 2024 Feb 19; Vol. 16 (1), pp. 35. Date of Electronic Publication: 2024 Feb 19.