Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alice Y Chuang"'
Autor:
Megan L Durr, Wojciech K Mydlarz, Chunbo Shao, Marianna L Zahurak, Alice Y Chuang, Mohammad O Hoque, William H Westra, Nanette J Liegeois, Joseph A Califano, David Sidransky, Patrick K Ha
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10828 (2010)
Methylation profiling of tumor suppressor gene (TSGs) promoters is quickly becoming a powerful diagnostic tool for the early detection, prognosis, and even prediction of clinical response to treatment. Few studies address this in salivary gland tumor
Externí odkaz:
https://doaj.org/article/ac6e9c54c38641f4aa5ff3b9f06610a6
Autor:
Fengshi Dong, Zili Zhai, Jeannette S. Messer, Alice Y. Chuang, David L. Boone, John H. Kwon, Feng Wu
Publikováno v:
Autophagy. 10:468-479
Multiple genetic studies have implicated the autophagy-related gene, ATG16L1, in the pathogenesis of Crohn disease (CD). While CD-related research on ATG16L1 has focused on the functional significance of ATG16L1 genetic variations, the mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639a8a06df2e51a8dcec35363a02f80e
https://doi.org/10.4161/auto.27553
https://doi.org/10.4161/auto.27553
Publikováno v:
Inflammatory Bowel Diseases. 20:126-135
Background Crohn's disease (CD) is associated with defective sensing of pathogens in genetically susceptible individuals. Nucleotide-binding oligomerization domain containing 2 (NOD2) mutations in coding regions are strongly linked to CD pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9234706fc55ccf2a1299ff1404f6a2f
https://doi.org/10.1097/01.mib.0000436954.70596.9b
https://doi.org/10.1097/01.mib.0000436954.70596.9b
Autor:
Alice Y. Chuang, Joseph A. Califano, Kavita M. Pattani, David Sidransky, Wayne M. Koch, Semra Demokan
Publikováno v:
Oncology Reports
Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In the present study, we assessed the association of epigenetic alterations of a panel of 12 genes [nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f335806afa9c31d481d47a5049c56ed
http://europepmc.org/articles/PMC3896520
http://europepmc.org/articles/PMC3896520
miR-106b Fine Tunes ATG16L1 Expression and Autophagic Activity in Intestinal Epithelial HCT116 Cells
Publikováno v:
Inflammatory Bowel Diseases. 19:2295-2301
MicroRNAs (miRNAs) are small RNA molecules that regulate over 30% of human protein-coding genes by binding to the 3'UTR of mRNAs that results in mRNA cleavage and/or translational arrest.1, 2 A single miRNA can regulate hundreds of genes simultaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f16d72b848200b44adaefa076ff4b2e
https://doi.org/10.1097/mib.0b013e31829e71cf
https://doi.org/10.1097/mib.0b013e31829e71cf
Alpha-Defens in 5 Expression is Regulated by microRNAs in the Caco-2 Intestinal Epithelial Cell Line
Publikováno v:
Journal of Inflammatory Bowel Diseases & Disorders.
Background: In inflammatory bowel disease (IBD), an inappropriate immune response leads to chronic mucosal inflammation. This response may be partly due to dysregulation of defensins, which are endogenously produced antimicrobial peptides. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d25ba8bd9c278a00d7177410e7878e
https://doi.org/10.4172/2476-1958.1000105
https://doi.org/10.4172/2476-1958.1000105
Publikováno v:
Cell Cycle. 10:3938-3947
The cisplatin-induced ATM-dependent phosphorylated (p)-ΔNp63α plays an important role in transcriptional regulation of specific genes encoding mRNAs and microRNAs (miRs) implicated in cell death, cell survival and chemoresistance. The p-ΔNp63α-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97ff582db105c39293da8a799deab46
https://doi.org/10.4161/cc.10.22.18107
https://doi.org/10.4161/cc.10.22.18107
Autor:
Arthur J. Sober, Timothy M. Johnson, Anthony P. Tufaro, Victor A. Neel, William H. Sharfman, Sharifeh Farasat, Nanette J. Liégeois, Martin C. Mihm, Paul Nghiem, Jatin P. Shah, Kishwer S. Nehal, Siegrid S. Yu, Clark C. Otley, Joseph A. Califano, Charles M. Balch, David R. Byrd, Thomas Lardaro, Alice Y. Chuang
Publikováno v:
Journal of the American Academy of Dermatology. 64:1051-1059
Background The incidence of cutaneous squamous cell carcinoma (cSCC) is increasing. Although most patients achieve complete remission with surgical treatment, those with advanced disease have a poor prognosis. The American Joint Committee on Cancer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbce1f488b6a1a31d177664c770adaf5
https://doi.org/10.1016/j.jaad.2010.08.033
https://doi.org/10.1016/j.jaad.2010.08.033
Autor:
Edward A. Ratovitski, Alice Y. Chuang, David Sidransky, Nanette J. Liégeois, Rose-Anne Romano, Yiping Huang, Barry Trink, Satrajit Sinha
Publikováno v:
Cell Cycle. 9:328-338
Cisplatin remains the most important chemotherapeutic agent for patients with human head and neck cancer. However, tumor cells often develop resistance to cisplatin-induced apoptosis. We previously found that head and neck squamous cell carcinoma (HN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3890f8b9f0a86c64d6e18c2dc4e8338
https://doi.org/10.4161/cc.9.2.10432
https://doi.org/10.4161/cc.9.2.10432
Autor:
Steven S. Chang, Patrick K. Ha, Wayne M. Koch, Joseph A. Califano, Alice Y. Chuang, Shaoyu Zhou, Tony C. Y. Chuang, William H. Westra, Shahnaz Begum
Publikováno v:
Oral Oncology. 44:915-919
Summary Human papillomavirus (HPV) 16 is present in up to 60% of patients with head and neck squamous cell carcinoma (HNSCC) and confers a favorable prognosis in terms of recurrence and mortality. Previous reports demonstrated that HPV-16 DNA can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c2dc735f197fd0cf783ed511259ee4
https://doi.org/10.1016/j.oraloncology.2008.01.001
https://doi.org/10.1016/j.oraloncology.2008.01.001