Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alice Y, Zhou"'
Autor:
Nancy D. Marin, Michelle Becker-Hapak, Wilbur M. Song, Quazim A. Alayo, Lynne Marsala, Naomi Sonnek, Melissa M. Berrien-Elliott, Mark Foster, Jennifer A. Foltz, Jennifer Tran, Pamela Wong, Celia C. Cubitt, Patrick Pence, Kimberly Hwang, Alice Y. Zhou, Miriam T. Jacobs, Timothy Schappe, David A. Russler-Germain, Ryan C. Fields, Matthew A. Ciorba, Todd A. Fehniger
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMetastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient (dMMR)/microsatellit
Externí odkaz:
https://doaj.org/article/989a296ad9bc48bf902f4f5ef1d3f555
Publikováno v:
JAAD Case Reports, Vol 48, Iss , Pp 59-61 (2024)
Externí odkaz:
https://doaj.org/article/53a0d1f37ebc46a79297a6765deed636
Autor:
Favour A. Akinjiyan, George Nassief, Jordan Phillipps, Tolulope Adeyelu, Andrew Elliott, Farah Abdulla, Alice Y. Zhou, George Souroullas, Kevin B. Kim, Ari Vanderwalde, Soo J. Park, George Ansstas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract ARID genes encode subunits of SWI/SNF chromatin remodeling complexes and are frequently mutated in human cancers. We investigated the correlation between ARID mutations, molecular features, and clinical outcomes in melanoma patients. Cutaneo
Externí odkaz:
https://doaj.org/article/12330a2b365b4ae9b93fc739ef7b1daa
Autor:
Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Since the T-box transcription factors (TFs) T-BET and EOMES are necessary for initiation of NK cell development, their ongoing requirement for mature NK cell homeostasis, function, and molecular programming remains unclear. To address this, T-BET and
Externí odkaz:
https://doaj.org/article/74062db604294ed99bc9e3922c1fadcb
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the management of several life-threatening malignancies, often achieving durable sustained responses. The number of patients treated with this new class of cell-based therapy, along wi
Externí odkaz:
https://doaj.org/article/1fc38d7eacb44074b7cfcd845335329b
Autor:
Melissa M. Berrien-Elliott, Jennifer A. Foltz, David A. Russler-Germain, Carly C. Neal, Jennifer Tran, Margery Gang, Pamela Wong, Bryan Fisk, Celia C. Cubitt, Nancy D. Marin, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Ethan McClain, Samantha Kersting-Schadek, Sweta Desai, Patrick Pence, Michelle Becker-Hapak, Jeremy Eisele, Matthew Mosior, Lynne Marsala, Obi L. Griffith, Malachi Griffith, Saad M. Khan, David H. Spencer, John F. DiPersio, Rizwan Romee, Geoffrey L. Uy, Camille N. Abboud, Armin Ghobadi, Peter Westervelt, Keith Stockerl-Goldstein, Mark A. Schroeder, Fei Wan, Wen-Rong Lie, Patrick Soon-Shiong, Allegra A. Petti, Amanda F. Cashen, Todd A. Fehniger
Publikováno v:
Sci Transl Med
Natural killer (NK) cells are innate lymphoid cells that eliminate cancer cells, produce cytokines, and are being investigated as a nascent cellular immunotherapy. Impaired NK cell function, expansion, and persistence remain key challenges for optima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d5b150b9fb46a2a7f0c16ecb5e95ee
https://europepmc.org/articles/PMC9210521/
https://europepmc.org/articles/PMC9210521/
Autor:
Omar H Butt, Alice Y Zhou, Jiayi Huang, William A Leidig, Alice E Silberstein, Milan G Chheda, Tanner M Johanns, George Ansstas, Jingxia Liu, Grayson Talcott, Ruth Nakiwala, Joshua S Shimony, Albert H Kim, Eric C Leuthardt, David D Tran, Jian L Campian
Publikováno v:
Neuro-Oncology Advances. 4
Autor:
Jingxia Liu, Jian Campian, Milan G Chheda, George Ansstas, William A Leidig, Joshua S. Shimony, David Tran, Alice E Silberstein, Jiayi Huang, Ruth Nakiwala, Omar H Butt, Grayson Talcott, Eric C. Leuthardt, Tanner Michael Johanns, Albert H. Kim, Alice Y Zhou
Publikováno v:
Neuro-oncology Advances
Background The blood-brain barrier (BBB) is a major limiting factor for drug delivery in brain tumors. Laser interstitial thermal therapy (LITT) disrupts the peritumoral BBB. In this study, we examine survival in patients with recurrent glioblastoma
Autor:
Omar H, Butt, Alice Y, Zhou, Paolo F, Caimi, Patrick H, Luckett, Julie K, Wisch, Paul-Robert, Derenoncourt, Kenneth, Lee, Gregory F, Wu, Marcos J G, de Lima, Jian L, Campian, Matthew J, Frank, John F, DiPersio, Armin, Ghobadi, Beau M, Ances
Publikováno v:
JAMA Oncology. 8:1652
ImportanceDetermining whether neurofilament light chain (NfL) elevations in patients who develop immune effector cell–associated neurotoxicity syndrome (ICANS) occur before or after infusion of cellular product is important to identify high-risk pa
Autor:
Stephen M. Dilworth, Natalia Ichaso, Adam Adamarek, Jitka Forstová, N J Dibb, Vojtech Zila, Alice Y. Zhou
Publikováno v:
Journal of Virology. 85:3046-3054
Murine polyomavirus middle T-antigen (MT) induces tumors by mimicking an activated growth factor receptor. An essential component of this action is a 22-amino-acid hydrophobic region close to the C terminus which locates MT to cell membranes. Here, w