Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alice Witsell"'
Autor:
Kelly Beagan, Robin L Armstrong, Alice Witsell, Upasana Roy, Nikolai Renedo, Amy E Baker, Orlando D Schärer, Mitch McVey
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006813 (2017)
Double strand breaks (DSBs) and interstrand crosslinks (ICLs) are toxic DNA lesions that can be repaired through multiple pathways, some of which involve shared proteins. One of these proteins, DNA Polymerase θ (Pol θ), coordinates a mutagenic DSB
Externí odkaz:
https://doaj.org/article/424f94cfac564df49822bba40c3fbed3
Publikováno v:
Fly. 4:137-140
Over the past two decades, a large collection of transposable elements inserted at various locations in the Drosophila melanogaster genome has been assembled. These transposons are frequently utilized in imprecise excision screens to generate deletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8891d1997b957ca15e94595ce04f03
https://doi.org/10.4161/fly.4.2.10918
https://doi.org/10.4161/fly.4.2.10918
Publikováno v:
The FASEB Journal. 19:1-19
The impact of aging on the cytokine response of human skeletal muscle to exercise-induced injury remains poorly understood. We enrolled physically active, young (23-35 years old, n=15) and old (66-78 years old, n=15) men to perform 45 min of downhill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a40e8d82c865d351880e0172670d4cf
https://doi.org/10.1096/fj.03-1286fje
https://doi.org/10.1096/fj.03-1286fje
Autor:
Alice Witsell, Amy Baker, Robin L. Armstrong, Orlando D. Schärer, Nikolai Renedo, Kelly Beagan, Upasana Roy, Mitch McVey
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 5, p e1006813 (2017)
PLoS Genetics, Vol 13, Iss 5, p e1006813 (2017)
Double strand breaks (DSBs) and interstrand crosslinks (ICLs) are toxic DNA lesions that can be repaired through multiple pathways, some of which involve shared proteins. One of these proteins, DNA Polymerase θ (Pol θ), coordinates a mutagenic DSB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f2609ce2308a4b84876695aecdc55f
https://doi.org/10.1371/journal.pgen.1006813
https://doi.org/10.1371/journal.pgen.1006813
Publikováno v:
Blood. 89:2376-2383
Administration of kit-ligand (KL) before and after doses of 5-fluorouracil (5-FU) results in marrow failure in mice, presumably because of enhanced KL-induced cycling of stem cells, which makes them more susceptible to the effects of 5-FU. In attempt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99274ce14e5e4675d0fe5bb3ae2ded2a
https://doi.org/10.1182/blood.v89.7.2376
https://doi.org/10.1182/blood.v89.7.2376
Publikováno v:
Blood. 86:4674-4680
Peripheral blood stem cells and progenitor cells, collected during recovery from exposure to cytotoxic agents or after cytokine administration, are being increasingly used in clinical bone marrow transplantation. To determine factors important for mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dcdaaf783e005a6d67c14e354c504c
https://doi.org/10.1182/blood.v86.12.4674.bloodjournal86124674
https://doi.org/10.1182/blood.v86.12.4674.bloodjournal86124674
Autor:
Khodaverdian, Varandt1 (AUTHOR), Sano, Tokio1 (AUTHOR), Maggs, Lara1 (AUTHOR), Tomarchio, Gina1 (AUTHOR), Dias, Ana1 (AUTHOR), Tran, Mai1 (AUTHOR), Clairmont, Connor1 (AUTHOR), McVey, Mitch1 (AUTHOR) mitch.mcvey@tufts.edu
Publikováno v:
PLoS Genetics. 7/29/2024, Vol. 20 Issue 7, p1-23. 23p.
Autor:
Martha J. Lundell, R. Brent Calder, Alice Witsell, Moonsook Lee, Robert N. Salomon, Mitch McVey, Justine S. Liepkalns, Ana Maria Garcia, Jan Vijg
Publikováno v:
Genome Biology
Background The BLM DNA helicase plays a vital role in maintaining genome stability. Mutations in BLM cause Bloom syndrome, a rare disorder associated with cancer predisposition and premature aging. Humans and mice with blm mutations have increased fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfc35d707f1084c4a08889d7505ac82
https://pubmed.ncbi.nlm.nih.gov/22183041
https://pubmed.ncbi.nlm.nih.gov/22183041
Transposable elements are frequently used in Drosophila melanogaster for imprecise excision screens to delete genes of interest. However, these screens are highly variable in the number and size of deletions that are recovered. Here, we show that con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bd67a75f528360f68048056e6160ea
https://europepmc.org/articles/PMC2778970/
https://europepmc.org/articles/PMC2778970/
Autor:
Beagan, Kelly1, Armstrong, Robin L.1, Witsell, Alice1, Roy, Upasana2, Renedo, Nikolai1, Baker, Amy E.1, Scharer, Orlando2,3, McVey, Mitch1 mitch.mcvey@tufts.edu
Publikováno v:
PLoS Genetics. 5/25/2017, Vol. 13 Issue 5, p1-19. 19p.