Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alice Ward Racca"'
Autor:
Jin-Kyu Park, Yibing Qyang, Jonas Schwan, Michael J. Rynkiewicz, Alice Ward Racca, Daniel Jacoby, Jeffrey R. Moore, Lorenzo R. Sewanan, Stuart G. Campbell, Nikolaos Papoutsidakis, William Lehman
Publikováno v:
Journal of General Physiology. 153
Hypertrophic cardiomyopathy (HCM) is an inherited disorder caused primarily by mutations to thick and thinfilament proteins. Although thin filament mutations are less prevalent than their oft-studied thick filament counterparts, they are frequently a
Autor:
Corrado Poggesi, Chiara Tesi, Alice Ward Racca, Michael R. Hoopmann, Cecilia Ferrantini, J. Manuel Pioner, Lil Pabon, Jordan M. Klaiman, Veronica Muskheli, Michael Regnier, Xuan Guan, Martin K. Childers, Deok Ho Kim, David L. Mack, Charles E. Murry, Robert L. Moritz, Jesse Macadangdang
Publikováno v:
Cardiovasc Res
Aims Heart failure invariably affects patients with various forms of muscular dystrophy (MD), but the onset and molecular sequelae of altered structure and function resulting from full-length dystrophin (Dp427) deficiency in MD heart tissue are poorl
Autor:
Michael J. Rynkiewicz, Alice Ward Racca, Nicholas LaFave, William Lehman, Jeffrey R. Moore, Anita Ghosh
Publikováno v:
J Biol Chem
Dilated cardiomyopathy (DCM) is associated with mutations in cardiomyocyte sarcomeric proteins, including α-tropomyosin. In conjunction with troponin, tropomyosin shifts to regulate actomyosin interactions. Tropomyosin molecules overlap via tropomyo
Autor:
J. Manuel Pioner, Michael J. Bamshad, Anita E. Beck, Alice Ward Racca, Farid Moussavi-Harami, Yuanhua Cheng, Michael Regnier, Jordan M. Klaiman
Publikováno v:
The Journal of Physiology. 594:437-452
The contractile properties of human fetal cardiac muscle have not yet been described and functional information has been primarily obtained via studies in vivo with echocardiography. Most of what is known about the contractile properties of developin
Autor:
Jeffrey R. Moore, Stephanie Jones, Michael J. Rynkiewicz, William Lehman, Nicholas LaFave, Alice Ward Racca
Publikováno v:
Biophysical Journal. 116:178a
Autor:
Vijay S. Rao, Galina V. Flint, Scott Lundy, Alice Ward Racca, Michael Regnier, Donald E. Born, Anita E. Beck, Michael J. Bamshad
Publikováno v:
The Journal of Physiology. 591:3049-3061
Little is known about the contraction and relaxation properties of fetal skeletal muscle, and measurements thus far have been made with non-human mammalian muscle. Data on human fetal skeletal muscle contraction are lacking, and there are no publishe
Autor:
Kai Chun Yang, Rebecca J. Zaunbrecher, Chiara Tesi, Mark Y. Jeong, Deok Ho Kim, Josè Manuel Pioner, Jordan M. Klaiman, Alice Ward Racca, David L. Mack, Charles E. Murry, Martin K. Childers, Lil Pabon, Corrado Poggesi, Michael Regnier, Veronica Muskheli, Xuan Guan, Jesse Macadangdang
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 885-896 (2016)
Stem Cell Reports
Stem Cell Reports
Summary Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Previous approaches have been limited due to the smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be627a85caeb998014f5f9c5d9625d11
http://hdl.handle.net/2158/1048856
http://hdl.handle.net/2158/1048856
Publikováno v:
Biophysical Journal. 112:263a-264a
Autor:
Michael Regnier, F. Steven Korte, Margaret J. McMillin, Michael J. Bamshad, Alice Ward Racca, Anita E. Beck
Distal arthrogryposis is the most common known heritable cause of congenital contractures (e.g. clubfoot) and results from mutations in genes that encode proteins of the contractile complex of skeletal muscle cells. Mutations are most frequently foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459366725d4d509f5ad01339e1d74e44
https://europepmc.org/articles/PMC4481580/
https://europepmc.org/articles/PMC4481580/
Autor:
Veronica Muskheli, Christian I. Childers, Xuan Guan, Corrado Poggesi, Lil Pabon, Alice Ward Racca, Charles E. Murry, David L. Mack, Michael Regnier, Jesse Macadangdang, Mark Y. Jeong, Deok Ho Kim, Josè Manuel Pioner, Martin K. Childers
Publikováno v:
Biophysical Journal. 108(2)
Duchenne Muscular Dystrophy (DMD) is a wasting disease of striated muscle resulting from membrane fragility. We modeled DMD cardiac disease using urine-derived cells from a patient, reprogrammed to induced pluripotent stem cells (hiPSCs) and differen