Výsledky vyhledávání - "Alice S. van Velzen"

Akademický článek

Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms

Autor: Maria T. Georgescu, Paul C. Moorehead, Alice S. van Velzen, Kate Nesbitt, Birgit M. Reipert, Katharina N. Steinitz, Maria Schuster, Christine Hough, David Lillicrap

Publikováno v: Haematologica, Vol 103, Iss 8 (2018)

The development of inhibitory antibodies to factor VIII is the most serious complication of replacement therapy in hemophilia A. Activation of the innate immune system during exposure to this protein contributes to inhibitor development. However, avo

Externí odkaz: https://doaj.org/article/795636410fc144f29549cf2ed3ff147e

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Akademický článek

Desmopressin in moderate hemophilia A patients: a treatment worth considering

Autor: Janneke I. Loomans, Marieke J.H.A. Kruip, Manuel Carcao, Shannon Jackson, Alice S. van Velzen, Marjolein Peters, Elena Santagostino, Helen Platokouki, Erik Beckers, Jan Voorberg, Johanna G. van der Bom, Karin Fijnvandraat, for the RISE consortium

Publikováno v: Haematologica, Vol 103, Iss 3 (2018)

Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed. Patients with a lower baseline factor VIII activity tend to show a reduced response, therefore, desmop

Externí odkaz: https://doaj.org/article/acbe979985fc47ecba83394ab98d4cc2

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Autor: Christoph Male, Michiel Coppens, Maria Elisa Mancuso, Samantha C. Gouw, Cedric Hermans, Daniel P. Hart, Britta A P Laros-van Gorkom, Johanna G. van der Bom, Johannes Oldenburg, Amal Abdi, Caroline Vuong, Giancarlo Castaman, Maria Gabriella Mazzucconi, Corien L. Eckhardt, Alice S. van Velzen, Simon McRae, Frank W.G. Leebeek, Karin Fijnvandraat

Publikováno v: Journal of Thrombosis and Haemostasis, 19, 9, pp. 2171-2181
Journal of thrombosis and haemostasis, 19(9), 2171-2181. Wiley-Blackwell
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, 19(9), 2171-2181. WILEY
Journal of thrombosis and haemostasis, Vol. 19, no. 9, p. 2171-2181 (2021)
Journal of Thrombosis and Haemostasis, 19(9), 2171-2181. Wiley-Blackwell Publishing Ltd
Journal of Thrombosis and Haemostasis, 19, 2171-2181

Background: Non-severe hemophilia A patients have a life-long inhibitor risk. Yet, no studies have analyzed risk factors for inhibitor development after 50 factor VIII (FVIII) exposure days (EDs). Objectives: This case-control study investigated trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd4e1e9eab275305819e25645eb7caf
https://doi.org/10.1111/jth.15419

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To serve and protect: The modulatory role of von Willebrand factor on factor VIII immunogenicity

Autor: Jan Voorberg, Robin B. Hartholt, Anja ten Brinke, Alice S. van Velzen, Ivan Peyron, Karin Fijnvandraat

Publikováno v: Blood Reviews. 31:339-347

Hemophilia A is a bleeding disorder characterized by the absence or dysfunction of blood coagulation factor VIII (FVIII). Patients are treated with regular infusions of FVIII concentrate. In response to treatment, approximately 30% of patients with s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157c1241a6b0f478598bd4f214c9deaf
https://doi.org/10.1016/j.blre.2017.07.001

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Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia a mice via thymic mechanisms

Autor: Kate Nesbitt, Katharina Nora Steinitz, Birgit M. Reipert, Alice S. van Velzen, Paul Moorehead, Christine Hough, David Lillicrap, Maria Schuster, Maria T. Georgescu

Publikováno v: Haematologica, 103(8), 1403-1413. Ferrata Storti Foundation
Haematologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa0b4c50cdf2fb3c8d986c7ec9d413e
https://pure.amc.nl/en/publications/dexamethasone-promotes-durable-factor-viiispecific-tolerance-in-hemophilia-a-mice-via-thymic-mechanisms(5cff90a1-e722-419f-a1e0-067bc16d2484).html

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Abstracts

Autor: Nina Streefkerk, Waander L. van Heerde, Berthold S. Iegmund, Thynn Thynn Yee, Ril Iesner, Elena Santagostino, Pieter Willem Kamphuisen, Eveline P. Mauser-Bunschoten, Carmen Escuriola-Ettingshausen, Paul P. T. Brons, Victor J. Imenez-Yuste, Daniel P. Hart, Corien L. Eckhardt, Maria Gabriella Mazzucconi, Kathelijne Peerlinck, Annarita Tagliaferri, Savita Rangarajan, Christoph Male, S Imon Mcrae, Natasja Dors, Marjolein Peters, P. Iercarla Schinco, Frans J. Smiers, Giancarlo Castaman, Karin Fijnvandraat, Helen Platokouki, M. Holmström, Russell Keenan, Johanna G. van der Bom, Britta A P Laros-van Gorkom, Marjon H. Cnossen, Frank W.G. Leebeek, Johannes Oldenburg, Charles R. M. Hay, Robert Klamroth, Anne Mäkipernaa, Cédric Hermans, Pia Petrini, Karly Hamulyák, Sylvia Reitter-Pfoertner, Saturnino Haya, Karina Meijer, Massimo Morfini, Alice S. van Velzen, M.R. Nijziel, Jan Astermark

Publikováno v: Haemophilia. 20:1-186

Introduction and Objectives: Neutralizing antibodies (inhibitors) directed against the FVIII protein may increase the bleeding frequency and compromise the management of bleeding episodes in nonsevere haemophilia A patients. The median annual bleedin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30c5c76954081782c79363d4319af764
https://doi.org/10.1111/hae.12400

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Emerging Issues in Diagnosis, Biology, and Inhibitor Risk in Mild Hemophilia A

Autor: Corien L. Eckhardt, Silvia Linari, Giancarlo Castaman, Karin Fijnvandraat, Alice S. van Velzen

Publikováno v: Seminars in thrombosis and hemostasis, 42(5), 507-512. Thieme Medical Publishers

Mild hemophilia A (MHA) is an X-linked bleeding disorder defined by factor VIII (FVIII) levels between 5 and 40 U/dL. Diagnosis occurs later in life compared with severe or moderate disease. Although bleeding episodes are especially posttraumatic, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2070f1c712ffab0938b65c1f8b015f
https://pure.amc.nl/en/publications/emerging-issues-in-diagnosis-biology-and-inhibitor-risk-in-mild-hemophilia-a(98a6b059-53e2-422f-933f-c1f5f9b1456a).html

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Feasibility of weaning and direct extubation from open lung high-frequency ventilation in preterm infants

Autor: Anton H. van Kaam, Anne De Jaegere, Alice S. van Velzen, Johanna van der Lee

Publikováno v: Pediatric critical care medicine, 10(1), 71-75. Lippincott Williams and Wilkins

Objective: High-frequency ventilation (HFV) is increasingly used in preterm infants, but data on weaning and extubation are limited. We aimed to establish if weaning the continuous distending pressure (CDP) below 8 cm H2O and the Fio2 below 0.30 is f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c7070168d4ef3953f3014f44fcc4d0
https://doi.org/10.1097/pcc.0b013e3181936fbe

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Effect of von Willebrand factor on inhibitor eradication in patients with severe haemophilia A: a systematic review

Autor: Karin Fijnvandraat, Marjolein Peters, Alice S. van Velzen, Johanna G. van der Bom

Publikováno v: British Journal of Haematology, 166(4), 485-495

Summary This systematic review was designed to summarize the reported valid quantitative evidence on the association between use of von Willebrand factor (VWF)-containing Factor VIII (FVIII) concentrates and successful immune tolerance induction (ITI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a217f547bcb01ae8d61256707a7bb800
http://hdl.handle.net/1887/101745

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