Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alice S. Wong"'
Publikováno v:
Oncogene. 39:4227-4240
Malignant ascites of epithelial ovarian cancer is a metastatic tumor microenvironment in which large amounts of disseminated single cells (DSCs) and disseminated tumor cell clusters (DTCCs) are commonly observed. The tumor cell clusters are known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ef6992f3dae6d85ef9b89445b3b980
https://doi.org/10.1038/s41388-020-1288-2
https://doi.org/10.1038/s41388-020-1288-2
Publikováno v:
The Journal of Neuroscience. 39:7576-7590
The hippocampus has been highly implicated in depression symptoms. Recent findings suggest that the expression and susceptibility of depression symptoms are related to the enhanced functioning of the hippocampus. We reasoned that hippocampal engrams,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d192536f786afe6ebb46006e0a4a08
https://doi.org/10.1523/jneurosci.1958-18.2019
https://doi.org/10.1523/jneurosci.1958-18.2019
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27215 (2011)
Stress exerts a profound impact on learning and memory, in part, through the actions of adrenal corticosterone (CORT) on synaptic plasticity, a cellular model of learning and memory. Increasing findings suggest that CORT exerts its impact on synaptic
Externí odkaz:
https://doaj.org/article/e48eea6b2b694ccf8b49aace2af13656
Publikováno v:
Cancer Research. 80:3707-3707
The tumor microenvironment is actively involved in cancer progression and is becoming an attractive therapeutic target. It is increasingly clear that both biotic and abiotic factors in the microenvironment play a crucial role in disease progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d4ec4ca14fb1804d163f09583158c0
https://doi.org/10.1158/1538-7445.am2020-3707
https://doi.org/10.1158/1538-7445.am2020-3707
Autor:
Yiu Chung Tse, Diane C. Lagace, Ixchel Montoya, Jennifer I. Lissemore, Axel Mathieu, Tak Pan Wong, Alice S. Wong
Publikováno v:
Hippocampus. 24:1120-1128
Hippocampal shrinkage is a commonly found neuroanatomical change in stress-related mood disorders such as depression and post-traumatic stress disorders (PTSD). Since the onset and severity of these disorders have been found to be closely related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f084c26c4218a6b7902f887a42240c88
https://doi.org/10.1002/hipo.22296
https://doi.org/10.1002/hipo.22296
Autor:
Rosemary C. Bagot, Alice S. Wong, Huy-Binh Nguyen, Yiu Chung Tse, Tak Pan Wong, Michael J. Meaney
Publikováno v:
Biological Psychiatry. 72:491-498
Variations in maternal care in the rat associate with robust differences in hippocampal development and synaptic plasticity in the offspring. Maternal care also influences pituitary-adrenal stress responses and corticosterone (CORT) regulation of hip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6e69e60f4e943ca9c829024fb9a17f
https://doi.org/10.1016/j.biopsych.2012.03.016
https://doi.org/10.1016/j.biopsych.2012.03.016
Publikováno v:
Cancer Research. 78:87-87
Ovarian cancer is highly metastatic with a poor prognosis. The p70 S6 kinase (p70S6K) is a downstream effector of the phosphatidylinositol-3 kinase/Akt pathway that is frequently activated in ovarian cancer. Constitutive activation of p70S6K is signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc69484457d29934a3224352843a1ee
https://doi.org/10.1158/1538-7445.am2018-87
https://doi.org/10.1158/1538-7445.am2018-87
Autor:
Kwai-Wa Cheng, Limin Li, Alice S. Wong, Nam-Kiu Tsing, Tuen-Wai Ng, Ching-Wan Tai, Wai-Ki Ching
Publikováno v:
International journal of data mining and bioinformatics. 4(3)
Many clustering techniques and classification methods for analysing microarray data require a complete dataset. However, very often gene expression datasets contain missing values due to various reasons. In this paper, we first propose to use vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb1814947286a28cb14233a91fac871
https://pubmed.ncbi.nlm.nih.gov/20681483
https://pubmed.ncbi.nlm.nih.gov/20681483
Publikováno v:
IET systems biology. 3(2)
It is well known that the control/intervention of some genes in a genetic regulatory network is useful for avoiding undesirable states associated with some diseases like cancer. For this purpose, both optimal finite-horizon control and infinite-horiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c7f021842a0e0579050803f5330824
https://pubmed.ncbi.nlm.nih.gov/19292563
https://pubmed.ncbi.nlm.nih.gov/19292563
Publikováno v:
Cancer Research. 74:1151-1151
Prostate cancer (PCa) is the most common cancer and the second leading cause of cancer related death in males in the developed countries. One of the major clinical challenges is the propensity for advanced PCa to metastasize to bone or other organs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4706d2236495cd8f2982954333a6054
https://doi.org/10.1158/1538-7445.am2014-1151
https://doi.org/10.1158/1538-7445.am2014-1151