Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Alice P Chen"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 1935-1939 (2021)
“Rare cancers” are a diverse collection of cancers that collectively account for approximately 20% of all adult cancers in the United States. Their rarity has caused an underrepresentation of these cancers in preclinical research and clinical tri
Externí odkaz:
https://doaj.org/article/cc494a37cc874161a23f8d6a23fb3085
Autor:
Jiuping Ji, Yiping Zhang, Christophe E Redon, William C Reinhold, Alice P Chen, Laura K Fogli, Susan L Holbeck, Ralph E Parchment, Melinda Hollingshead, Joseph E Tomaszewski, Quentin Dudon, Yves Pommier, James H Doroshow, William M Bonner
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171582 (2017)
Phosphorylated H2AX (γ-H2AX) is a sensitive marker for DNA double-strand breaks (DSBs), but the variability of H2AX expression in different cell and tissue types makes it difficult to interpret the meaning of the γ-H2AX level. Furthermore, the assa
Externí odkaz:
https://doaj.org/article/c5271db0c4334b48803bddf775b6a904
Autor:
Thomas F. Tropea, Whitney Hartstone, Noor Amari, Dylan Baum, Jacqueline Rick, Eunran Suh, Hanwen Zhang, Rachel A. Paul, Noah Han, Rebecca Zack, Eliza M. Brody, Isabela Albuja, Justin James, Meredith Spindler, Andres Deik, Whitley W. Aamodt, Nabila Dahodwala, Ali Hamedani, Aaron Lasker, Howard Hurtig, Matthew Stern, Daniel Weintraub, Pavan Vaswani, Allison W. Willis, Andrew Siderowf, Sharon X. Xie, Vivianna Van Deerlin, Alice S. Chen-Plotkin
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Observational studies in Parkinson’s disease (PD) deeply characterize relatively small numbers of participants. The Molecular Integration in Neurological Diagnosis Initiative seeks to characterize molecular and clinical features of every P
Externí odkaz:
https://doaj.org/article/1b40d637ebd5495caa965d0b43455e9e
Autor:
Sanaz Arezoumandan, Katheryn A.Q. Cousins, Daniel T. Ohm, MaKayla Lowe, Min Chen, James Gee, Jeffrey S. Phillips, Corey T. McMillan, Kelvin C. Luk, Andres Deik, Meredith A. Spindler, Thomas F. Tropea, Daniel Weintraub, David A. Wolk, Murray Grossman, Virginia Lee, Alice S. Chen‐Plotkin, Edward B. Lee, David J. Irwin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 673-685 (2024)
Abstract Objective Alzheimer's disease neuropathologic change and alpha‐synucleinopathy commonly co‐exist and contribute to the clinical heterogeneity of dementia. Here, we examined tau epitopes marking various stages of tangle maturation to test
Externí odkaz:
https://doaj.org/article/cdc2ad75ef8743d99fac2e3feb9bcc6b
Autor:
Kellie Alleyne-Mike, John Glod, Erissa Cuffie, Rajiv Kissoon, Bernard Bedaysie, Pearse Sylvester, Matthew Boron, J. Michelle Brockman, Nancy Moore, Alice P. Chen, Elad Sharon
Publikováno v:
JCO Global Oncology, Vol , Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/8f352b9955984488997c76d59617c564
Autor:
Daniel Weintraub, Marijan Posavi, Pierre Fontanillas, Thomas F. Tropea, Eugenia Mamikonyan, Eunran Suh, John Q. Trojanowski, Paul Cannon, Vivianna M. Van Deerlin, andMe Research Team, Alice S. Chen‐Plotkin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 936-949 (2022)
Abstract Objective To develop a clinico‐genetic predictor of impulse control disorder (ICD) risk in Parkinson's disease (PD). Methods In 5770 individuals from three PD cohorts (the 23andMe, Inc.; the University of Pennsylvania [UPenn]; and the Park
Externí odkaz:
https://doaj.org/article/39bf7dd46847460688de1fbf2db005c3
Autor:
Monica K. Malhotra, Shalu Pahuja, Brian F. Kiesel, Leonard J. Appleman, Fei Ding, Yan Lin, Hussein A. Tawbi, Ronald G. Stoller, James J. Lee, Chandra P. Belani, Alice P. Chen, Vincent L. Giranda, Stacie Peacock Shepherd, Leisha A. Emens, S. Percy Ivy, Edward Chu, Jan H. Beumer, Shannon Puhalla
Publikováno v:
Breast Cancer Research and Treatment. 198:487-498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807df4048513cc6c111834d7987ddddd
https://doi.org/10.1007/s10549-023-06889-0
https://doi.org/10.1007/s10549-023-06889-0
Autor:
Amy S. Clark, Fangxin Hong, Richard S. Finn, Angela M. DeMichele, Edith P. Mitchell, James Zwiebel, Fernanda I. Arnaldez, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Stanley R. Hamilton, Mehmet S. Copur, Samer S. Kasbari, Ravneet Thind, Barbara A. Conley, Carlos L. Arteaga, Peter J. O'Dwyer, Lyndsay N. Harris, Alice P. Chen, Keith T. Flaherty
Publikováno v:
Clinical Cancer Research. 29:1477-1483
Purpose: Cyclin D/CDK4/6 is critical in controlling the G1 to S checkpoint. CCND, the gene encoding cyclin D, is known to be amplified in a variety of solid tumors. Palbociclib is an oral CDK4/6 inhibitor, approved in advanced breast cancer in combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0deaba3a14fb4dcac6730d29e90dbb46
https://doi.org/10.1158/1078-0432.ccr-22-2150
https://doi.org/10.1158/1078-0432.ccr-22-2150
Autor:
Delphine S. Tuot, Clare Liddy, Varsha G. Vimalananda, Jennifer Pecina, Elizabeth J. Murphy, Erin Keely, Steven R. Simon, Frederick North, Jay D. Orlander, Alice Hm Chen
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Electronic consultation is an emerging mode of specialty care delivery that allows primary care providers and their patients to obtain specialist expertise without an in-person visit. While studies of individual programs have demo
Externí odkaz:
https://doaj.org/article/05ddf22d3ad940c6bb788952afb907e9
Autor:
James Nguyen, Naoko Takebe, Shivaani Kummar, Albiruni Razak, Sant P. Chawla, Suzanne George, Shreyaskumar R. Patel, Mary Louise Keohan, Sujana Movva, Geraldine O'Sullivan Coyne, Khanh Do, Lamin Juwara, Brooke Augustine, Seth M. Steinberg, Laura Kuhlmann, S. Percy Ivy, James H. Doroshow, Alice P. Chen
Publikováno v:
Clinical Cancer Research. 29:1200-1208
Purpose: Alveolar soft part sarcoma (ASPS) is a rare, highly vascular tumor with few treatment options. We designed a phase II randomized trial to determine the activity and tolerability of single-agent cediranib or sunitinib in patients with advance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed830b53ecb0a730e3001c430b8fc8da
https://doi.org/10.1158/1078-0432.ccr-22-2145
https://doi.org/10.1158/1078-0432.ccr-22-2145