Zobrazeno 1 - 10
of 406
pro vyhledávání: '"Alice P Chen"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 1935-1939 (2021)
“Rare cancers” are a diverse collection of cancers that collectively account for approximately 20% of all adult cancers in the United States. Their rarity has caused an underrepresentation of these cancers in preclinical research and clinical tri
Externí odkaz:
https://doaj.org/article/cc494a37cc874161a23f8d6a23fb3085
Autor:
Jiuping Ji, Yiping Zhang, Christophe E Redon, William C Reinhold, Alice P Chen, Laura K Fogli, Susan L Holbeck, Ralph E Parchment, Melinda Hollingshead, Joseph E Tomaszewski, Quentin Dudon, Yves Pommier, James H Doroshow, William M Bonner
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171582 (2017)
Phosphorylated H2AX (γ-H2AX) is a sensitive marker for DNA double-strand breaks (DSBs), but the variability of H2AX expression in different cell and tissue types makes it difficult to interpret the meaning of the γ-H2AX level. Furthermore, the assa
Externí odkaz:
https://doaj.org/article/c5271db0c4334b48803bddf775b6a904
Autor:
Daniel Weintraub, Marijan Posavi, Pierre Fontanillas, Thomas F. Tropea, Eugenia Mamikonyan, Eunran Suh, John Q. Trojanowski, Paul Cannon, Vivianna M. Van Deerlin, andMe Research Team, Alice S. Chen‐Plotkin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 936-949 (2022)
Abstract Objective To develop a clinico‐genetic predictor of impulse control disorder (ICD) risk in Parkinson's disease (PD). Methods In 5770 individuals from three PD cohorts (the 23andMe, Inc.; the University of Pennsylvania [UPenn]; and the Park
Externí odkaz:
https://doaj.org/article/39bf7dd46847460688de1fbf2db005c3
Autor:
Emre Gok, Mehmet H. Akay, Ismael Salas de Armas, Kimberly Klein, Hlaing Tint, Paul M. Allison, Alice J. Chen, Bindu Akkanti, Biswajit Kar, Igor D. Gregoric
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-4 (2021)
Abstract Background Patients with acquired hemophilia A (AHA) who require open heart surgery have a life-threatening risk of hemorrhage. Limited data exist to guide perioperative management of these patients. Case presentation A 53-year-old female wi
Externí odkaz:
https://doaj.org/article/9a7ca3716f0e4a748fd8be1fdbba72ea
Autor:
Sarah R. Yoder, Allison B. Lonstein, Arth Sharma, John Garcia-Munoz, Rafael Moreno, Alice Y. Chen, Grace Orben, Tiana Clemons, Madison Masters, Lala L. Forrest, Ikhianosen Ukhuedoba, Julianne M. Hall
Publikováno v:
Education Sciences, Vol 12, Iss 9, p 586 (2022)
PEARLS (Perspectives on Equity Advancement: Research and Learning Symposium) was a student-led, faculty-mentored, year-long initiative culminating in a symposium with three components: (1) “Change Agents”, where faculty leaders presented their re
Externí odkaz:
https://doaj.org/article/bb4c22e475ee493498989f38df221754
Autor:
Monica K. Malhotra, Shalu Pahuja, Brian F. Kiesel, Leonard J. Appleman, Fei Ding, Yan Lin, Hussein A. Tawbi, Ronald G. Stoller, James J. Lee, Chandra P. Belani, Alice P. Chen, Vincent L. Giranda, Stacie Peacock Shepherd, Leisha A. Emens, S. Percy Ivy, Edward Chu, Jan H. Beumer, Shannon Puhalla
Publikováno v:
Breast Cancer Research and Treatment. 198:487-498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807df4048513cc6c111834d7987ddddd
https://doi.org/10.1007/s10549-023-06889-0
https://doi.org/10.1007/s10549-023-06889-0
Autor:
Amy S. Clark, Fangxin Hong, Richard S. Finn, Angela M. DeMichele, Edith P. Mitchell, James Zwiebel, Fernanda I. Arnaldez, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Stanley R. Hamilton, Mehmet S. Copur, Samer S. Kasbari, Ravneet Thind, Barbara A. Conley, Carlos L. Arteaga, Peter J. O'Dwyer, Lyndsay N. Harris, Alice P. Chen, Keith T. Flaherty
Publikováno v:
Clinical Cancer Research. 29:1477-1483
Purpose: Cyclin D/CDK4/6 is critical in controlling the G1 to S checkpoint. CCND, the gene encoding cyclin D, is known to be amplified in a variety of solid tumors. Palbociclib is an oral CDK4/6 inhibitor, approved in advanced breast cancer in combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0deaba3a14fb4dcac6730d29e90dbb46
https://doi.org/10.1158/1078-0432.ccr-22-2150
https://doi.org/10.1158/1078-0432.ccr-22-2150
Autor:
James Nguyen, Naoko Takebe, Shivaani Kummar, Albiruni Razak, Sant P. Chawla, Suzanne George, Shreyaskumar R. Patel, Mary Louise Keohan, Sujana Movva, Geraldine O'Sullivan Coyne, Khanh Do, Lamin Juwara, Brooke Augustine, Seth M. Steinberg, Laura Kuhlmann, S. Percy Ivy, James H. Doroshow, Alice P. Chen
Publikováno v:
Clinical Cancer Research. 29:1200-1208
Purpose: Alveolar soft part sarcoma (ASPS) is a rare, highly vascular tumor with few treatment options. We designed a phase II randomized trial to determine the activity and tolerability of single-agent cediranib or sunitinib in patients with advance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed830b53ecb0a730e3001c430b8fc8da
https://doi.org/10.1158/1078-0432.ccr-22-2145
https://doi.org/10.1158/1078-0432.ccr-22-2145
Autor:
Philippe L. Bedard, Shuli Li, Kari B. Wisinski, Eddy S. Yang, Sewanti A. Limaye, Edith P. Mitchell, James A. Zwiebel, Jeffrey A. Moscow, Robert J. Gray, Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David R. Patton, P. Mickey Williams, Stanley R. Hamilton, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O'Dwyer, Alice P. Chen, Keith T. Flaherty
Publikováno v:
JCO precision oncology. 6
PURPOSE National Cancer Institute–Molecular Analysis for Therapy Choice is a multicohort trial that assigns patients with advanced cancers to targeted therapies on the basis of central tumor genomic testing. Arm B evaluated afatinib, an ErbB family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bf59fabbdedba6f33eccff12578795
https://pubmed.ncbi.nlm.nih.gov/35939768
https://pubmed.ncbi.nlm.nih.gov/35939768
Autor:
Senthil, Damodaran, Fengmin, Zhao, Dustin A, Deming, Edith P, Mitchell, John J, Wright, Robert J, Gray, Victoria, Wang, Lisa M, McShane, Larry V, Rubinstein, David R, Patton, P Mickey, Williams, Stanley R, Hamilton, Jennifer M, Suga, Barbara A, Conley, Carlos L, Arteaga, Lyndsay N, Harris, Peter J, O'Dwyer, Alice P, Chen, Keith T, Flaherty
Publikováno v:
J Clin Oncol
Activating mutations in PIK3CA are observed across multiple tumor types. The NCI-MATCH (EAY131) is a tumor-agnostic platform trial that enrolls patients to targeted therapies on the basis of matching genomic alterations. Arm Z1F evaluated copanlisib,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfbcd9071baf869343e1deaeda8697f7
https://pubmed.ncbi.nlm.nih.gov/35133871
https://pubmed.ncbi.nlm.nih.gov/35133871