Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alice Migazzi"'
Autor:
Ramachandran Prakasam, Angela Bonadiman, Roberta Andreotti, Emanuela Zuccaro, Davide Dalfovo, Caterina Marchioretti, Debasmita Tripathy, Gianluca Petris, Eric N. Anderson, Alice Migazzi, Laura Tosatto, Anna Cereseto, Elena Battaglioli, Gianni Sorarù, Wooi Fang Lim, Carlo Rinaldi, Fabio Sambataro, Naemeh Pourshafie, Christopher Grunseich, Alessandro Romanel, Udai Bhan Pandey, Andrea Contestabile, Giuseppe Ronzitti, Manuela Basso, Maria Pennuto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Here, Prakasam and colleagues show that polyQ-expanded androgen receptor toxicity can be attenuated using artificial miRNAs targeting Lsd1 and Prmt6, two AR-co-activators overexpressed in an androgen-dependent manner specifically in skeletal muscle,
Externí odkaz:
https://doaj.org/article/9fd52a5a537f405caa90331491bb84a3
Autor:
Arianna Manini, Tommaso Bocci, Alice Migazzi, Edoardo Monfrini, Dario Ronchi, Giulia Franco, Anna De Rosa, Ferdinando Sartucci, Alberto Priori, Stefania Corti, Giacomo Pietro Comi, Nereo Bresolin, Manuela Basso, Alessio Di Fonzo
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Mutations in TGM6 gene, encoding for transglutaminase 6 (TG6), have been implicated in the pathogenesis of spinocerebellar ataxia type 35 (SCA35), a rare autosomal dominant disease marked by cerebellar degeneration and characteriz
Externí odkaz:
https://doaj.org/article/6a5f6dd8716f4871a5e1487ed447e030
Autor:
Alice Migazzi, Chiara Scaramuzzino, Eric N. Anderson, Debasmita Tripathy, Ivó H. Hernández, Rogan A. Grant, Michela Roccuzzo, Laura Tosatto, Amandine Virlogeux, Chiara Zuccato, Andrea Caricasole, Tamara Ratovitski, Christopher A. Ross, Udai B. Pandey, José J. Lucas, Frédéric Saudou, Maria Pennuto, Manuela Basso
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108980- (2021)
Summary: The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is disru
Externí odkaz:
https://doaj.org/article/4ec24cea628a418d9972d9f2b7afcdb5
Autor:
Debasmita Tripathy, Alice Migazzi, Federica Costa, Alessandro Roncador, Pamela Gatto, Federica Fusco, Lucia Boeri, Diego Albani, J. Leon Juárez-Hernández, Carlo Musio, Laura Colombo, Mario Salmona, M.M. Micha Wilhelmus, Benjamin Drukarch, Maria Pennuto, Manuela Basso
Publikováno v:
Neurobiology of Disease, Vol 140, Iss , Pp 104849- (2020)
Alzheimer's disease (AD) is the most common cause of dementia. At the pre-symptomatic phase of the disease, the processing of the amyloid precursor protein (APP) produces toxic peptides, called amyloid-β 1–42 (Aβ 1–42). The downstream effects o
Externí odkaz:
https://doaj.org/article/c936871dc947473aa3b05bf9282ee7ec
Autor:
Luca Marsili, Jennifer Sharma, Alberto J. Espay, Alice Migazzi, Elhusseini Abdelghany, Emily J. Hill, Kevin R. Duque, Matthew C. Hagen, Christopher D. Stephen, Gabor G. Kovacs, Anthony E. Lang, Marios Hadjivassiliou, Manuela Basso, Marcelo A. Kauffman, Andrea Sturchio
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7292 (2021)
The gold standard for classification of neurodegenerative diseases is postmortem histopathology; however, the diagnostic odyssey of this case challenges such a clinicopathologic model. We evaluated a 60-year-old woman with a 7-year history of a progr
Externí odkaz:
https://doaj.org/article/7ae52b70500343c29f13e64ded63079a
Autor:
Frédéric Saudou, Maria Pennuto, Michela Roccuzzo, Tamara Ratovitski, Ivó H. Hernández, José J. Lucas, Chiara Scaramuzzino, Laura Tosatto, Rogan A. Grant, Amandine Virlogeux, Manuela Basso, Christopher A. Ross, Debasmita Tripathy, Andrea Caricasole, Eric N. Anderson, Alice Migazzi, Chiara Zuccato, Udai Bhan Pandey
Publikováno v:
A: Pathogenic mechanisms.
Background Neuronal function depends heavily on the ability to transport various molecules along axons. The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development through
Autor:
Emily J. Hill, Andrea Sturchio, Matthew C. Hagen, Jennifer S. Sharma, Manuela Basso, Marios Hadjivassiliou, Anthony E. Lang, Kevin R Duque, Luca Marsili, Marcelo Andrés Kauffman, Alberto J. Espay, Alice Migazzi, Christopher D. Stephen, Gabor G. Kovacs, Elhusseini Abdelghany
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7292, p 7292 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 7292, p 7292 (2021)
The gold standard for classification of neurodegenerative diseases is postmortem histopathology; however, the diagnostic odyssey of this case challenges such a clinicopathologic model. We evaluated a 60-year-old woman with a 7-year history of a progr
Autor:
Eric N. Anderson, Laura Tosatto, Alice Migazzi, Maria Pennuto, Tamara Ratovitski, Udai Bhan Pandey, Rogan A. Grant, Christopher A. Ross, Michela Roccuzzo, Ivó H. Hernández, Chiara Scaramuzzino, Chiara Zuccato, Amandine Virlogeux, Debasmita Tripathy, Andrea Caricasole, Manuela Basso, Frédéric Saudou, José J. Lucas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, Vol 35, Iss 2, Pp 108980-(2021)
Cell reports
instname
Cell Reports, Vol 35, Iss 2, Pp 108980-(2021)
Cell reports
SUMMARY The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a1d50ffffbb2b303aa6536f7c1f419
http://hdl.handle.net/10261/265719
http://hdl.handle.net/10261/265719
Autor:
Laura Pasetto, Maurizio Grassano, Silvia Pozzi, Silvia Luotti, Eliana Sammali, Alice Migazzi, Manuela Basso, Giovanni Spagnolli, Emiliano Biasini, Edoardo Micotti, Milica Cerovic, Mirjana Carli, Gianluigi Forloni, Giovanni De Marco, Umberto Manera, Cristina Moglia, Gabriele Mora, Bryan J Traynor, Adriano Chiò, Andrea Calvo, Valentina Bonetto
Publikováno v:
Brain
Aggregation and cytoplasmic mislocalization of TDP-43 are pathological hallmarks of amyotrophic lateral sclerosis and frontotemporal dementia spectrum. However, the molecular mechanism by which TDP-43 aggregates form and cause neurodegeneration remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf78ea1ae88379eba481f8b339d7903b
http://hdl.handle.net/11572/334710
http://hdl.handle.net/11572/334710
Autor:
Giulia Franco, Arianna Manini, Alice Migazzi, Anna De Rosa, Tommaso Bocci, Ferdinando Sartucci, Alberto Priori, Dario Ronchi, Stefania Corti, Nereo Bresolin, Giacomo P. Comi, Edoardo Monfrini, Manuela Basso, Alessio Di Fonzo
Publikováno v:
BMC Neurology
BMC Neurology, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Neurology, Vol 20, Iss 1, Pp 1-7 (2020)
Background Mutations in TGM6 gene, encoding for transglutaminase 6 (TG6), have been implicated in the pathogenesis of spinocerebellar ataxia type 35 (SCA35), a rare autosomal dominant disease marked by cerebellar degeneration and characterized by pos