Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alice Melotti"'
Autor:
Alice Melotti, Christophe Mas, Monika Kuciak, Aiala Lorente‐Trigos, Isabel Borges, Ariel Ruiz i Altaba
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 10, Pp 1263-1278 (2014)
Abstract Constitutive activation of canonical WNT‐TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT‐TCF antagonists in clinical use. We have performed a repositioning screen for WNT‐TCF
Externí odkaz:
https://doaj.org/article/0847a9c96622445d943063c107ec027f
Autor:
Arnaud Duquet, Alice Melotti, Sonakshi Mishra, Monica Malerba, Chandan Seth, Arwen Conod, Ariel Ruiz i Altaba
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 7, Pp 882-901 (2014)
Abstract The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used c
Externí odkaz:
https://doaj.org/article/9335cc5f8719458cbd007765a16efc97
Autor:
Patrizio Castagnola, Giorgio Corte, Walter Giaretti, Alice Melotti, Massimo Maffei, Francesco Romeo, Antonio Daga, Marina Fabbi, Andrea Fabiano, Emanuela Biollo, Massimiliano Monticone
Supplementary Figures S1-S6 and Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4fd2c0856d4862fb1aae7bb6118068
https://doi.org/10.1158/1541-7786.22519332.v1
https://doi.org/10.1158/1541-7786.22519332.v1
Autor:
Ariel Ruiz i Altaba, Sonakshi Mishra, Alice Melotti, Monica Malerba, Chandan Seth, Arnaud Duquet, Arwen Conod
Publikováno v:
EMBO Molecular Medicine. 6:882-901
The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used cloned cel
Autor:
Antonio Daga, Francesco Romeo, Emanuela Biollo, Andrea Fabiano, Alice Melotti, Giorgio Corte, Massimiliano Monticone, Massimo E. Maffei, Marina Fabbi, Patrizio Castagnola, W. Giaretti
Publikováno v:
Molecular Cancer Research. 7:1822-1834
γ-secretase inhibitors have been proposed as drugs able to kill cancer cells by targeting the NOTCH pathway. Here, we investigated two of such inhibitors, the Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle) and the N-[N-(3,5-difluorophenacetyl)-l-alanyl]-
Autor:
Tullio Florio, Carola Porcile, Alessandra Pattarozzi, Monica Gatti, Antonio Daga, Michele Lo Casto, Daniela Marubbi, Maria Cristina Capra, Federica Barbieri, Renato Spaziante, Roberto E. Favoni, Fabrizio Griffero, Adriana Bajetto, Giorgio Corte, Alice Melotti, Gianluigi Zona
Publikováno v:
Journal of Biological Chemistry. 284:7138-7148
Because a subpopulation of cancer stem cells (tumor-initiating cells, TICs) is believed to be responsible for the development, progression, and recurrence of many tumors, we evaluated the in vitro sensitivity of human glioma TICs to epidermal growth
Autor:
Ariel Ruiz i Altaba, Alice Melotti, Isabel Borges, Aiala Lorente-Trigos, Christophe Mas, Monika Kuciak
Publikováno v:
EMBO Molecular Medicine, Vol. 6, No 10 (2014) pp. 1263-78
EMBO Molecular Medicine
EMBO Molecular Medicine
Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed a repositioning screen for WNT-TCF response block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5520774022efc3afb6510a94f0fb7ad5
https://archive-ouverte.unige.ch/unige:44224
https://archive-ouverte.unige.ch/unige:44224
Publikováno v:
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 54 (2010)
BMC Cancer, Vol 10, Iss 1, p 54 (2010)
Background Malignant pleural mesothelioma is a rare disease known to be resistant to conventional therapies. A better understanding of mesothelioma biology may provide the rationale for new therapeutic strategies. In this regard, tumor cell lines dev
Publikováno v:
Journal of Molecular Cell Biology, Vol. 2, No 6 (2010) pp. 318-332
Human colon carcinomas (CCs) represent a growing worldwide problem. One of the pathways that has been negatively implicated in the genesis of CCs is triggered by bone morphogenetic protein (BMP) ligands, which activate BMP receptors leading to the fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb277813401786f01ea197b2035a9631
https://archive-ouverte.unige.ch/unige:21092
https://archive-ouverte.unige.ch/unige:21092
Autor:
Daniela Marubbi, Lorenzo Moretta, Alessandro Moretta, Fabrizio Griffero, Alice Melotti, Renato Spaziante, Giorgio Corte, Cristina Bottino, Francesca Bellora, Roberta Castriconi, Pietro Luigi Poliani, Antonio Daga, Alessandra Dondero, Gianluigi Zona
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(6)
In this study, cancer cells were isolated from tumor specimens of nine glioblastoma patients. Glioblastoma cells, cultured under suitable culture conditions, displayed markers typical of neural stem cells, were capable of partial multilineage differe