Výsledky vyhledávání - "Alice Mbewe-Mvula"

Akademický článek

Pre-clinical development of BCG.HIVA(CAT), an antibiotic-free selection strain, for HIV-TB pediatric vaccine vectored by lysine auxotroph of BCG.

Autor: Narcís Saubi, Alice Mbewe-Mvula, Ester Gea-Mallorqui, Maximillian Rosario, Josep Maria Gatell, Tomáš Hanke, Joan Joseph

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42559 (2012)

In the past, we proposed to develop a heterologous recombinant BCG prime-recombinant modified vaccinia virus Ankara (MVA) boost dual pediatric vaccine platform against transmission of breast milk HIV-1 and Mycobacterium tuberculosis (Mtb). In this st

Externí odkaz: https://doaj.org/article/b5153ceba5934a599a900bf8d4ebad93

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Pre-clinical development of BCG.HIVA(CAT) strain, an antibiotic-free selection strain for HIV-TB pediatric vaccine

Autor: Tomáš Hanke, Joan Joseph, Ester Gea-Mallorquí, Narcís Saubi, Alice Mbewe-Mvula, C Hurtado, José M. Gatell

Publikováno v: Retrovirology
Retrovirology, Vol 9, Iss Suppl 2, p P352 (2012)

Background Our starting platform was based on a heterologous BCG prime and MVA boost regimen delivering a common immunogen called HIVA. In this study, we have i) developed a BCG.HIVA strain containing an antibiotic free selection system (Cobra); ii)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a394ee1a9f0a1cfb99f274e05a7b966
https://doi.org/10.1186/1742-4690-9-s2-p352

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Optimizing delivery of HIV-1 conserved region-derived immunogen for induction of T and B cell responses in rhesus macaques

Autor: Alice Mbewe-Mvula, C. J. Melief, David Price, G Koopman, JW Drijfhout, Tomáš Hanke, P. Liljestrom, R Wagner, E. D. Quakkelaar, Nicola Borthwick, S. Colloca, Maximillian Rosario, ML Knudsen, A. Nicosia

Publikováno v: Retrovirology
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Background The complexity of candidate HIV-1 vaccine formulations is increasing due to extreme challenges faced when trying to prevent or control HIV-1 infection. Methods Immunogen HIVconsv based on the most conserved regions of the HIV-1 proteome wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b71aa4e4667ef193fa5ca3ccd6ed94d
https://ora.ox.ac.uk/objects/uuid:eb2a0ab9-0d22-403d-8bf0-98957d0d8adb

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Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors

Autor: Alice Mbewe-Mvula, Gerald W. Both, Anne Bridgeman, Tomáš Hanke, Jerald C. Sadoff, Richard Hopkins, Joan Joseph, John Fulkerson, Charles Bourne

Publikováno v: European Journal of Immunology. 41:3542-3552

The desire to induce HIV-1-specific responses soon after birth to prevent breast milk transmission of HIV-1 led us to propose a vaccine regimen which primes HIV-1-specific T cells using a recombinant Mycobacterium bovis bacillus Calmette-Guérin (rBC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9a9513eec29e7053f3381ac4e8e85f
https://doi.org/10.1002/eji.201141962

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Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine

Autor: Maria Kakoulidou, Alfredo Nicosia, Peter Liljeström, Maximillian Rosario, Alice Mbewe-Mvula, Anne Bridgeman, Tomáš Hanke, Maria L. Knudsen, Daniel X. Johansson, Karl Ljungberg, Arturo Reyes-Sandoval

Publikováno v: Journal of Virology

Vaccination using “naked” DNA is a highly attractive strategy for induction of pathogen-specific immune responses; however, it has been only weakly immunogenic in humans. Previously, we constructed DNA-launched Semliki Forest virus replicons (DRE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd899790819fc21523834dedf82abef2
http://hdl.handle.net/11588/571659

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Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques

Autor: Alice Mbewe-Mvula, Nicola Borthwick, Anne Bridgeman, Guillaume Stewart-Jones, Esther D. Quakkelaar, Jan W. Drijfhout, Cornelis J. M. Melief, David C. Montefiori, Andrew J. McMichael, Maximillian Rosario, Alfredo Nicosia, Tomáš Hanke, Stefano Colloca

Publikováno v: AIDS, 26(3), 275-284
AIDS

Objectives: Administration of synthetic long peptides (SLPs) derived from human papillomavirus to cervical cancer patients resulted in clinical benefit correlated with expansions of tumour-specific T cells. Because vaginal mucosa is an important port

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2534853cf99e241d796fc99e6b78e9b2
https://pubmed.ncbi.nlm.nih.gov/22095198

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Pre-clinical development of BCG.HIVA(CAT), an antibiotic-free selection strain, for HIV-TB pediatric vaccine vectored by lysine auxotroph of BCG

Autor: Narcís Saubi, Maximillian Rosario, Ester Gea-Mallorquí, Joan Joseph, Tomáš Hanke, Josep M. Gatell, Alice Mbewe-Mvula

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42559 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe0a00d2d355617e9cd77ecbe9f877
http://hdl.handle.net/2445/124795

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