Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alice M. Bennett"'
Autor:
Alice M. Bennett, Robert J. Phillpotts, M. Gill Hartley, Freda K. Stevenson, Stuart D. Perkins, Roman A. Lukaszewski
Publikováno v:
Vaccine. 23:1931-1940
In some species DNA vaccines elicit potent humoral and cellular immune responses. However, their performance in humans and non-human primates is less impressive. There are suggestions in the literature that an increase in the intercellular distributi
Autor:
Aisling M. O’Dowd, Helen S. Garmory, Stuart D. Perkins, Richard W. Titball, Margaret Morton, Alice M. Bennett, Kate F. Griffin, Arthur K. Turner
Publikováno v:
Vaccine. 22:2524-2532
A recombinant strain of attenuated Salmonella enterica serovar Typhi surface-expressing Yersinia pestis F1 antigen was generated by transforming strain BRD1116 (aroA aroC htrA) with plasmid pAH34L encoding the Y. pestis caf operon. BRD1116/pAH34L was
Publikováno v:
Vaccine. 21:3110-3117
A DNA vaccine was constructed which expressed the binding domain of Clostridium botulinum neurotoxin serotype F fused to a signal peptide. Three intra-muscular doses fully protected Balb/c mice against 10(4) MLD of serotype F toxin. Priming of the im
Publikováno v:
Journal of General Virology. 84:1091-1100
Simian herpes B virus (SHBV) is the herpes simplex virus (HSV) homologue for the species MACACA: Unlike in its natural host, and unlike other animal herpesviruses, SHBV causes high mortality in accidentally infected humans. SHBV-infected cells, like
Autor:
R.J Beedham, Stuart D. Perkins, Alice M. Bennett, Les Baillie, Ethel Diane Williamson, Julie Miller
Publikováno v:
Vaccine. 20:2933-2941
The protective antigen (PA) of Bacillus anthracis and the V antigen of Yersinia pestis are potent immunogens and candidate vaccine sub-units. When plasmid DNA encoding either PA or V antigen was used to immunise the Balb/c mouse, a low serum IgG titr
Autor:
Susan C Jacobs, Robert J. Phillpotts, E. Diane Williamson, Stuart D Perkins, Alice M. Bennett
Publikováno v:
Vaccine. 18:588-596
Plasmids expressing the V antigen of Yersinia pestis or the E2 glycoprotein of Venezuelan Equine Encephalitis (VEE) virus were used to vaccinate mice by intra-dermal or intra-muscular injection, or by particle-mediated bombardment using the Helios™
Publikováno v:
Vaccine. 18:153-159
Yersinia pestis, the causative organism of plague, produces V antigen (LcrV), a bifunctional protein with regulatory and virulence roles that has been shown to be highly protective against a plague challenge. A combined sub-unit vaccine, comprising r
Publikováno v:
Journal of Medical Virology. 57:47-56
Herpes B virus infects naturally monkeys of the macaque genus in whom it can cause recurrent oral and genital lesions. However, when the virus infects humans it causes a neurological illness with a high case fatality rate. Successful treatment is pos
Publikováno v:
Viral Immunology. 11:109-117
An improved vaccine is needed against Venezuelan equine encephalitis (VEE) virus because the existing live attenuated vaccine, TC-83, causes a high incidence of adverse effects, and the Formalin-inactivated vaccine, C-84, does not protect against air
Autor:
Andrew J. Davison, Alice M. Bennett, Sharon Carr, Gavin William Grahame Wilkinson, Robert J. Phillpotts, Susan C. Jacobs
Publikováno v:
The Journal of general virology. 85(Pt 11)
Human adenovirus 4 (HAdV-4), the only serotype of the species HAdV-E to be isolated from man, was first identified by its association with outbreaks of acute respiratory disease in military recruits. To combat such outbreaks, a live, oral HAdV-4 vacc