Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alice M C, Martins"'
Autor:
Rayanne H. N. Silva, Emanuel P. Magalhães, Rebeca C. Gomes, Yunierkis Perez-Castillo, Alice M. C. Martins, Damião P. de Sousa
Publikováno v:
Applied Sciences, Vol 13, Iss 20, p 11585 (2023)
Neglected tropical diseases (NTDs) cause thousands of deaths each year. Among these diseases, we find Chagas disease, whose etiologic agent is Trypanosoma cruzi. Piplartine is an alkamide present in various species of the genus Piper that possess try
Externí odkaz:
https://doaj.org/article/241f6e5e19cf40b58a3eb1caf6a69517
Autor:
Carlos S. M. B. Filho, Ramon R. P. P. B. de Menezes, Emanuel P. Magalhães, Yunierkis P. Castillo, Alice M. C. Martins, Damião P. de Sousa
Publikováno v:
Molecules, Vol 28, Iss 11, p 4512 (2023)
Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options for the treatment of CD are limited, and parasite resistance has been reported. Piplartine is
Externí odkaz:
https://doaj.org/article/ad0196f4ddb249488e9f6f5eb026422d
Autor:
Sousa, Carlos S. M. B. Filho, Ramon R. P. P. B. de Menezes, Emanuel P. Magalhães, Yunierkis P. Castillo, Alice M. C. Martins, Damião P. de
Publikováno v:
Molecules; Volume 28; Issue 11; Pages: 4512
Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options for the treatment of CD are limited, and parasite resistance has been reported. Piplartine is
Autor:
Yasmim Mendes Rocha, Emanuel Paula Magalhães, Marlos de Medeiros Chaves, Márcia Machado Marinho, Valentina Nascimento e Melo de Oliveira, Ronaldo Nascimento de Oliveira, Tiago Lima Sampaio, Ramon R. P. P. B. de Menezes, Alice M. C. Martins, Roberto Nicolete
Publikováno v:
Parasitology Research. 121:2141-2156
Chagas disease (CD) is a neglected disease, prevalent and endemic in Latin America, but also present in Europe and North America. The main treatment used for this disease is benznidazole, but its efficacy is variable in the chronic phase and presents
Autor:
Eveline M. Bezerra, João R. Bezerra-Neto, Francisco A. M. Sales, Ricardo P. dos Santos, Alice M. C. Martins, Pedro de Lima-Neto, Ewerton W. S. Caetano, Eudenilson L. Albuquerque, Valder N. Freire
Publikováno v:
Molecules, Vol 19, Iss 4, Pp 4145-4156 (2014)
UV-vis optical absorption spectra of the antitrypanocidal drug benznidazole solvated in water were measured for various concentrations. The spectra show a prominent peak around 3.80 eV, while deconvolution of the UV-vis optical absorption spectra rev
Externí odkaz:
https://doaj.org/article/d39e8c6def5f4b9fbdc41ca4ade3be55
Autor:
Ramon R P P B de Menezes, Clarissa P Mello, Dânya B Lima, Louise D Tessarolo, Tiago Lima Sampaio, Lívia C F Paes, Natacha T Q Alves, Eudmar M Assis Junior, Roberto C P Lima Junior, Marcos H Toyama, Alice M C Martins
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151029 (2016)
Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and its isolated components directly interfere on cellular metabolism, causing alterations such
Externí odkaz:
https://doaj.org/article/0af3a44bf23943439dbdc5b11807119e
Autor:
Isabel C O Morais, Gustavo J S Pereira, M Orzáez, Roberta J B Jorge, Claudia Bincoletto, Marcos H Toyama, Helena S A Monteiro, Soraya S Smaili, Enrique Pérez-Payá, Alice M C Martins
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132569 (2015)
Acute renal failure is a common complication caused by Bothrops viper envenomation. In this study, the nefrotoxicity of a main component of B. leucurus venom called L-aminoacid oxidase (LAAO-Bl) was evaluated by using tubular epithelial cell lines MD
Externí odkaz:
https://doaj.org/article/ba5439495a064c35a771431df9349306
Autor:
Alba F C Torres, Chen Huang, Cheong-Meng Chong, Siu Wai Leung, Alvaro R B Prieto-da-Silva, Alexandre Havt, Yves P Quinet, Alice M C Martins, Simon M Y Lee, Gandhi Rádis-Baptista
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87556 (2014)
BACKGROUND: Dinoponera quadriceps is a predatory giant ant that inhabits the Neotropical region and subdues its prey (insects) with stings that deliver a toxic cocktail of molecules. Human accidents occasionally occur and cause local pain and systemi
Externí odkaz:
https://doaj.org/article/7ad82a2ead9e4b77a817bda1e55f7fd3
Autor:
Ramon R P P B, de Menezes, Alba F C, Torres, Thiala S J, da Silva, Daniel F, de Sousa, Danya B, Lima, Diva B, Norjosa, Nádia A P, Nogueira, Maria F, Oliveira, Márcia R, de Oliveira, Helena S A, Monteiro, Alice M C, Martins
Publikováno v:
Natural product communications. 7(1)
The therapeutic potential of toxins has aroused great interest in the scientific community. Microbial resistance is a serious current public health problem, in part because of the wide use of antimicrobial drugs. Furthermore, there are several proble
Autor:
Roberta J B, Jorge, Alice M C, Martins, Isabel C O, Morais, Rafael M, Ximenes, Felipe A R, Rodrigues, Bruno M, Soares, Janaina S A M, Evangelista, Marcos H, Toyama, Aline M A, Martins, Manoel O, Moraes Filho, Helena S A, Monteiro
Publikováno v:
Journal of experimental therapeuticsoncology. 9(3)
Animal venoms are complex mixtures of proteins and non proteins components with several biological activities. Snake venoms represent an essentially unexplored source of bioactive compounds that may cure disease conditions which do not respond to cur