Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alice L.-F. Mui"'
Autor:
Abrar Samiea, Jeff S. J. Yoon, Christopher J. Ong, Amina Zoubeidi, Thomas C. Chamberlain, Alice L.-F. Mui
Publikováno v:
Prostate Cancer, Vol 2020 (2020)
Interleukin-10 (IL10) is best studied for its inhibitory action on immune cells and ability to suppress an antitumour immune response. But IL10 also exerts direct effects on nonimmune cells such as prostate cancer epithelial cells. Elevated serum lev
Externí odkaz:
https://doaj.org/article/bc6b7ee61bac411b9c6eba4813cc37ea
Autor:
Thomas C. Chamberlain, Sylvia T. Cheung, Jeff S.J. Yoon, Andrew Ming-Lum, Bernd R. Gardill, Soroush Shakibakho, Edis Dzananovic, Fuqiang Ban, Abrar Samiea, Kamaldeep Jawanda, John Priatel, Gerald Krystal, Christopher J. Ong, Artem Cherkasov, Raymond J. Andersen, Sean A. McKenna, Filip Van Petegem, Alice L-F. Mui
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101433- (2020)
Summary: The anti-inflammatory actions of interleukin-10 (IL10) are thought to be mediated primarily by the STAT3 transcription factor, but pro-inflammatory cytokines such as interleukin-6 (IL6) also act through STAT3. We now report that IL10, but no
Externí odkaz:
https://doaj.org/article/6d1dc8ece1fe49e58498e3b24c40bfc5
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71336 (2013)
The anti-inflammatory cytokine interleukin-10 (IL-10) is essential for attenuating the inflammatory response, which includes reducing the expression of pro-inflammatory microRNA-155 (miR-155) in lipopolysaccharide (LPS) activated macrophages. miR-155
Externí odkaz:
https://doaj.org/article/04789a1b4b5e4a1fb187a9ef5bafa9e9
Autor:
Kamaldeep Jawanda, Christopher J. Ong, Soroush Shakibakho, Filip Van Petegem, Thomas C. Chamberlain, Edis Dzananovic, Fuqiang Ban, Sylvia T. Cheung, Bernd R. Gardill, Jeff S. J. Yoon, Raymond J. Andersen, Andrew Ming-Lum, Artem Cherkasov, John J. Priatel, Sean A. McKenna, Abrar Samiea, Gerald Krystal, Alice L.-F. Mui
The anti-inflammatory actions of interleukin-10 (IL10) are thought to be mediated primarily by the STAT3 transcription factor, but pro-inflammatory cytokines such as interleukin-6 (IL6) also act through STAT3. We now report that IL10, but not IL6 sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78413ed51d0ff77ae4b6e3593eac57cc
https://doi.org/10.1101/2020.05.29.123943
https://doi.org/10.1101/2020.05.29.123943
Autor:
Amina Zoubeidi, Christopher J. Ong, Thomas C. Chamberlain, Jeff S. J. Yoon, Abrar Samiea, Alice L.-F. Mui
Publikováno v:
Prostate Cancer, Vol 2020 (2020)
Prostate Cancer
Prostate Cancer
Interleukin-10 (IL10) is best studied for its inhibitory action on immune cells and ability to suppress an antitumour immune response. But IL10 also exerts direct effects on nonimmune cells such as prostate cancer epithelial cells. Elevated serum lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51b13de6eebcf410f3b5b8492f13e6f
https://doaj.org/article/bc6b7ee61bac411b9c6eba4813cc37ea
https://doaj.org/article/bc6b7ee61bac411b9c6eba4813cc37ea
Autor:
Amina Zoubeidi, Liangliang Liu, James W. Peacock, Kevin J. Tam, Shahram Khosravi, Kevin C.K. Lee, Norihiro Hayashi, Christopher J. Ong, Wilson C.W. Lee, Masaki Shiota, Takashi Dejima, Martin E. Gleave, Daniel H. F. Hui, Nader Al Nakouzi, Larissa Ivanova, Nastaran Khazamipour, Daksh Thaper, Hidetoshi Kuruma, Ladan Fazli, Tabitha Tombe, Parvin Yenki, Ivy Z. F. Jiao, Alice L.-F. Mui, Mads Daugaard, Ario Takeuchi
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 2, Pp 219-238 (2018)
EMBO Molecular Medicine
EMBO Molecular Medicine
Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cd212df39db9680a800250ee32a82f
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
https://doaj.org/article/2f44866b8d6c48509b92457ef60f92f1
Autor:
Peter T W Kim, Brad G Hoffman, Annette Plesner, Cheryl D Helgason, C Bruce Verchere, Stephen W Chung, Garth L Warnock, Alice L F Mui, Christopher J Ong
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14146 (2010)
Pluripotent embryonic stem cells hold a great promise as an unlimited source of tissue for treatment of chronic diseases such as Type 1 diabetes. Herein, we describe a protocol using all-trans-retinoic acid, basic fibroblast growth factor and dibutyr
Externí odkaz:
https://doaj.org/article/7d56353c45af4bfab4d144d96218cca8
Autor:
Abrar Samiea, Sean A. McKenna, Bernd R. Gardill, Andrew Ming-Lum, Jeff S. J. Yoon, Christopher J. Ong, Soroush Shakibakho, Artem Cherkasov, Gerald Krystal, Filip Van Petegem, Alice L.-F. Mui, Kamaldeep Jawanda, Thomas C. Chamberlain, Fuqiang Ban, John J. Priatel, Edis Dzananovic, Raymond J. Andersen, Sylvia T. Cheung
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101433-(2020)
iScience
iScience
Summary The anti-inflammatory actions of interleukin-10 (IL10) are thought to be mediated primarily by the STAT3 transcription factor, but pro-inflammatory cytokines such as interleukin-6 (IL6) also act through STAT3. We now report that IL10, but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38aaa3f6f9fac15fa4f897b99f0b7c15
https://doi.org/10.1016/j.isci.2020.101433
https://doi.org/10.1016/j.isci.2020.101433
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230427 (2020)
PLoS ONE
PLoS ONE
Macrophage cells form part of our first line defense against pathogens. Macrophages become activated by microbial products such as lipopolysaccharide (LPS) to produce inflammatory mediators, such as TNFα and other cytokines, which orchestrate the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa42edcb84719fe4128a027167a83bb
https://doi.org/10.1371/journal.pone.0230427
https://doi.org/10.1371/journal.pone.0230427
Autor:
Matt Nodwell, Lu Yang, Labros G. Meimetis, Xiaoxia Wang, Thomas MacRury, Curtis Harwig, Raymond J. Andersen, Gerald Krystal, Andrew Ming-Lum, Brian O. Patrick, Christopher J. Ong, Lloyd F Mackenzie, Grant R. Stenton, Joyce Wu, Alice L.-F. Mui
Publikováno v:
European Journal of Organic Chemistry. 2012:5195-5207
Two biomimetic approaches have been used to synthesize analogs of the SHIP1-activating sponge meroterpenoid pelorol (1). One approach started from the chiral pool plant natural product sclareolide, which has the same absolute configuration as pelorol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06199c0bd34810670417c007101a2ebb
https://doi.org/10.1002/ejoc.201200631
https://doi.org/10.1002/ejoc.201200631