Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alice L. Stone"'
Autor:
Joel Voldman, John G. Hildebrand, David M. Otten, Thomas L. Daniel, W.M. Tsang, Richard B. Levine, Alice L. Stone, Zane N. Aldworth
Publikováno v:
Journal of Neuroscience Methods. 204:355-365
We developed microfabricated flexible neural probes (FNPs) to provide a bi-directional electrical link to the moth Manduca sexta. These FNPs can deliver electrical stimuli to, and capture neural activity from, the insect's central nervous system. The
Publikováno v:
Journal of Biomedical Materials Research Part A. :811-818
During the typical healing response to an implanted biomaterial, vascular-rich granulation tissue forms around the implant and later resolves into a relatively avascular, fibrous capsule. We have previously shown that a microvascular construct (MVC)
Autor:
Joel Voldman, Alice L. Stone, John G. Hildebrand, Tom L Daniel, Akintunde Ibitayo Akinwande, Wei Mong Tsang, Zane N. Aldworth
Publikováno v:
IEEE Transactions on Biomedical Engineering. 57:1757-1764
We describe a flexible multisite microelectrode for insect flight biasing using neural stimulation. The electrode is made of two layers of polyimide (PI) with gold sandwiched in between in a split-ring geometry. The split-ring design in conjunction w
Autor:
John G. Hildebrand, Zane N. Aldworth, Joel Voldman, Thomas L. Daniel, Patrick P. Mercier, Anantha P. Chandrakasan, Denis C. Daly, Alice L. Stone, M. Bhardwaj
Publikováno v:
ISSCC
For decades, scientists and engineers have been fascinated by cybernetic organisms, or cyborgs, that fuse artificial and natural systems. Cyborgs enable harnessing biological systems that have been honed by evolutionary forces over millennia to achie
Publikováno v:
Tissue Engineering Part A. 14:433-440
Islet transplantation for the purpose of treating insulin-sensitive diabetes is currently limited by several factors, including islet survival posttransplantation. In the current study, a tissue-engineered prevascularized pancreatic encapsulating dev
Autor:
Jeffrey J. Rodriguez, Kirk W. Gossage, Alice L. Stone, Jennifer K. Barton, Elizabeth Kanter, Lida P. Hariri, Stuart K. Williams, Cynthia M. Smith
Publikováno v:
Physics in Medicine and Biology. 51:1563-1575
Optical coherence tomography (OCT) is an imaging modality capable of acquiring cross-sectional images of tissue using back-reflected light. Conventional OCT images have a resolution of 10-15 microm, and are thus best suited for visualizing tissue lay
Autor:
Kameha R. Kidd, James B. Hoying, Stuart K. Williams, Donny B. Dal Ponte, Raymond B. Nagle, Alice L. Stone
Publikováno v:
Tissue Engineering. 11:1379-1391
Biomedical implants often exhibit poor clinical performance due to the formation of a periimplant avascular fibrous capsule. Surface modification of synthetic materials has been evaluated to accelerate the formation of functional microcirculation in
Autor:
Robert Parkhill, Alice L. Stone, Mark W. Simpkins, Cynthia M. Smith, Robert L. Stewart, William L. Warren, Stuart K. Williams, Anatoly Kachurin
Publikováno v:
Tissue Engineering. 10:1566-1576
The primary emphasis of tissue engineering is the design and fabrication of constructs for the replacement of nonfunctional tissue. Because tissue represents a highly organized interplay of cells and extracellular matrix, the fabrication of replaceme
Autor:
Michael W. Riggs, Roberta M. O’Connor, Lance E. Perryman, Alice L. Stone, Michael S. Scherman, Michael R. McNeil
Publikováno v:
Infection and Immunity. 67:1317-1322
The protozoan parasite Cryptosporidium parvum is an important cause of diarrhea in humans, calves, and other mammals worldwide. No approved vaccines or parasite-specific drugs are currently available for the control of cryptosporidiosis. To effective
Autor:
Joel Voldman, Akintunde I. Akinwande, John G. Hildebrand, Richard B. Levine, W.M. Tsang, Thomas L. Daniel, Zane N. Aldworth, Alice L. Stone, David M. Otten
Publikováno v:
2010 IEEE 23rd International Conference on Micro Electro Mechanical Systems (MEMS).
We report the first remote flight control of an insect using microfabricated flexible neuroprosthetic probes (FNPs) that directly interface with the animal's central nervous system. The FNPs have a novel split-ring design that incorporates the anatom