Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alice L. Bodnar"'
Autor:
Raymond S. Hurst, Vincent E. Groppi, Bruce N. Rogers, Alice L. Bodnar, Theron M. Wall, Luz A. Cortes-Burgos, Jason K. Myers, Dac M. Dinh, Nicole R. Higdon, Mark L. Wolfe, Erik H. F. Wong, Karen K. Cook, Mihály Hajós, William E. Hoffmann
Publikováno v:
Journal of Medicinal Chemistry. 48:905-908
A library of benzamides was tested for alpha7 nicotinic acetylcholine receptor (nAChR) agonist activity using a chimeric receptor in a functional, cell-based, high-throughput assay. From this library, quinuclidine benzamides were found to have alpha7
Autor:
Anthony W. Yem, W. Rodney Mathews, Atli Thorarensen, Michael John Bohanon, Michael T. Sweeney, Timothy P. Boyle, Cindy L Wolfe, Charlotte L. Heckaman, Keith R. Marotti, Martin R. Deibel, Alice L. Bodnar, Gary E. Zurenko
Publikováno v:
Bioconjugate Chemistry. 15:333-343
Screening of our compound collection identified PNU-92560, a 2-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxamide, as a novel antibacterial agent. Extensive analogue development identified that the 2-position of the thiadiazole could be functionalized