Výsledky vyhledávání - "Alice Kawata"

Low dose antibiotic ingestion potentiates systemic and microbiome changes induced by silver nanoparticles

Autor: Azam F. Tayabali, Matthew J. Meier, Kathy C. Nguyen, Philip S. Shwed, Karen Leingartner, Michael G. Wade, M. Navarro, A. Wong, Alice Kawata, Marc Rigden, L.A. Beaudette, Jennifer Crosthwait, Alison C. Holloway

Publikováno v: NanoImpact. 23

Changes in the mammalian gut microbiome are linked to the impairment of immunological function and numerous other pathologies. Antimicrobial silver nanoparticles (AgNPs) are incorporated into numerous consumer products (e.g., clothing, cosmetics, foo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b8429a76ec18d7913c8334367db5ff
https://pubmed.ncbi.nlm.nih.gov/35559844

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Exposure to Low Doses of Dechlorane Plus Promotes Adipose Tissue Dysfunction and Glucose Intolerance in Male Mice

Autor: Ella Atlas, Vian Peshdary, Alexander Sorisky, Alice Kawata, George Styles, Marc Rigden, Don Caldwell

Publikováno v: Endocrinology. 161(8)

The prevalence of type 2 diabetes (T2D) continues to increase worldwide. It is well established that genetic susceptibility, obesity, overnutrition and a sedentary life style are risk factors for the development of T2D. However, more recently, studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150f2a484d5707d74c5154d2ead33fbd
https://pubmed.ncbi.nlm.nih.gov/32556108

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Gestational and Lactational Exposure to an Environmentally-Relevant Mixture of Brominated Flame Retardants: Effects on Neurodevelopment and Metabolism

Autor: Marc Rigden, Barbara F. Hales, Alison C. Holloway, Bernard Robaire, Don Caldwell, Alice Kawata, Wayne J. Bowers, Emily W. Y. Tung, Michael G. Wade

Publikováno v: Birth Defects Research. 109:497-512

Background Developmental exposure to brominated flame retardants (BFRs), including polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD), has been associated with impaired neurodevelopment and some symptoms of metabolic syndrome.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee2fdff039fe53adf1413c0a0c623da2
https://doi.org/10.1002/bdr2.1021

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Toxicity of Flame Retardant Isopropylated Triphenyl Phosphate: Liver, Adrenal, and Metabolic Effects

Autor: Don Caldwell, Alice Kawata, Alison C. Holloway, Michael G. Wade, Marc Rigden

Publikováno v: International journal of toxicology. 38(4)

The use of organophosphates phosphate flame retardants, particularly isopropylated triphenyl phosphate (IPTPP), has increased in recent years as replacements for polybrominated diphenyl ethers. This is despite limited understanding of the hazards of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea66da2e07297115055f5cc53d34d85
https://pubmed.ncbi.nlm.nih.gov/31132918

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Gestational and Early Postnatal Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants: General Toxicity and Skeletal Variations

Autor: Emily W. Y. Tung, Dorothea F. K. Rawn, Robert G. Berger, Michael G. Wade, Bernard Robaire, Han Yan, Barbara F. Hales, Pavine L.C. Lefèvre, Dean W. Gaertner, Marc Rigden, Alice Kawata

Publikováno v: Birth Defects Research Part B: Developmental and Reproductive Toxicology. 107:157-168

Brominated flame retardants (BFRs) are stable environmental contaminants known to exert endocrine-disrupting effects. Developmental exposure to polybrominated diphenyl ethers (PBDEs) is correlated with impaired thyroid hormone signaling, as well as e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c184930a5bf7e550579182b46f5dfc94
https://doi.org/10.1002/bdrb.21180

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Bisphenol A increases aP2 expression in 3T3L1 by enhancing the transcriptional activity of nuclear receptors at the promoter

Autor: Alice Kawata, Jonathan G. Boucher, Adèle Boudreau, Ella Atlas, Louise Pope, Michael G. Wade

Publikováno v: Adipocyte

Environmental pollutants, such as bisphenol A (BPA), have the potential to affect the differentiation processes and the biology of the adipose tissue. The 3T3-L1 model is one of the murine cell models used extensively for the investigation of the mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a03dfde08fef0a4111fdd4422350c6d
https://doi.org/10.4161/adip.28436

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Gestational and Lactational Exposure to an Environmentally-Relevant Mixture of Brominated Flame Retardants: Effects on Neurodevelopment and Metabolism

Autor: Emily W Y, Tung, Alice, Kawata, Marc, Rigden, Wayne J, Bowers, Don, Caldwell, Alison C, Holloway, Bernard, Robaire, Barbara F, Hales, Michael G, Wade

Publikováno v: Birth Defects Research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c2061dbaad7756f39bbaa4c8037dfb9c
https://pubmed.ncbi.nlm.nih.gov/28398660

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Gestational and Early Postnatal Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants: General Toxicity and Skeletal Variations

Autor: Emily W Y, Tung, Han, Yan, Pavine L C, Lefèvre, Robert G, Berger, Dorothea F K, Rawn, Dean W, Gaertner, Alice, Kawata, Marc, Rigden, Bernard, Robaire, Barbara F, Hales, Michael G, Wade

Publikováno v: Birth defects research. Part B, Developmental and reproductive toxicology. 107(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9501c0dbac1bb1570dfd146b7224cfc
https://pubmed.ncbi.nlm.nih.gov/27286044

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Methoxyacetic Acid-Induced Spermatocyte Death Is Associated with Histone Hyperacetylation in Rats1

Autor: Andrew Williams, Michael G. Wade, Alice Kawata, Carole L. Yauk

Publikováno v: Biology of Reproduction. 78:822-831

We used high-density microarrays to evaluate the possible mechanisms by which 2-methoxyacetic acid (MAA) disrupts spermatogenesis. Levels of mRNA transcripts were determined in total RNA isolated from testes of MAA-treated (650 mg/kg i.p.) or concurr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a844bcd12a613848968f35a856ea00e
https://doi.org/10.1095/biolreprod.107.065151

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Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice

Autor: Andrew Williams, Michael G. Wade, Amanda J. MacFarlane, Nathalie A. Behan, Alice Kawata, Breanne G. Swayne, Carole L. Yauk

Publikováno v: Mutation research. 737(1-2)

To date, fewer than 50 mutagens have been studied for their ability to cause heritable mutations. The majority of those studied are classical mutagens like radiation and anti-cancer drugs. Very little is known about the dietary variables influencing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0689e775af88869d2ef526251808469
https://pubmed.ncbi.nlm.nih.gov/22824165

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