Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alice J. Canaan"'
Publikováno v:
Biopharmaceutics & Drug Disposition. 19:395-400
Photodynamic therapy (PDT) using the photosensitizer BPD-Verteporfin (liposomal benzoporphyrin derivative-monoacid ring A) has been shown in previous studies to be effective in the amelioration of inflammatory arthritis in both the MRL-lpr mouse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a47f0485bbc75d452610a6f3e8eeda2
https://doi.org/10.1002/(sici)1099-081x(199809)19:6<395::aid-bdd117>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199809)19:6<395::aid-bdd117>3.0.co
Publikováno v:
Photochemistry and Photobiology. 62:169-175
Benzoporphyrin derivative monoacid ring A (BPD), a hydrophobic chlorin-like porphyrin derivative, which fluoresces strongly at 690 nm, may have potential for both oncologic and nononcologic applications in photodynamic therapy (PDT). To study the inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639990df97f22eed2c3379bb3dc33086
https://doi.org/10.1111/j.1751-1097.1995.tb05254.x
https://doi.org/10.1111/j.1751-1097.1995.tb05254.x
Autor:
Alice J. Canaan, Anna M. Richter, Ashok K. Jain, Elizabeth Waterfield, Beth Anne Allison, Julia G. Levy
Publikováno v:
Photochemistry and Photobiology. 57:1000-1006
Biodistribution studies were carried out on 14C-labeled benzoporphyrin derivative monoacid ring A (BPD), which had been formulated as a unilamellar liposome or taken from a stock solution in dimethyl sulfoxide diluted into phosphate-buffered saline i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eceac67bdc6ee7588a30b263659fc03
https://doi.org/10.1111/j.1751-1097.1993.tb02962.x
https://doi.org/10.1111/j.1751-1097.1993.tb02962.x
Autor:
Julia G. Levy, Alice J. Canaan, Ashok K. Jain, Elizabeth Waterfield, Ethan Sternberg, Anna M. Richter
Publikováno v:
Biochemical Pharmacology. 43:2349-2358
Benzoporphyrin derivative, monoacid ring A (BPD-MA), currently in clinical trials as a photosensitizer for photodynamic therapy for cancer, consists of two regioisomers (A1 and A2) present in equal proportions. The contribution of the regioisomers to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76911c3de4a02e059c9ccc74e5ccc317
https://doi.org/10.1016/0006-2952(92)90313-8
https://doi.org/10.1016/0006-2952(92)90313-8
Autor:
Alice J. Canaan, John Robert North, Ethan Sternberg, Anna M. Richter, Angela Cho, Claire Smits, Lina Hong, Ron Boch, David Dolphin, Ashok K. Jain
Publikováno v:
Photochemistry and photobiology. 82(1)
A newly synthesized diethylene glycol functionalized chlorin-type photosensitizer, lemuteporfin, was characterized for use in photodynamic therapy (PDT) in a panel of in vitro and in vivo test systems. The photosensitizer was highly potent, killing c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b713342f8e8c31ffcbc49d89b3bc7c8a
https://pubmed.ncbi.nlm.nih.gov/16097861
https://pubmed.ncbi.nlm.nih.gov/16097861
Autor:
Janice North, Anna M. Richter, Guillermo O. Simkin, Robert D. Bower, Julia G. Levy, Ashok K. Jain, Alice J. Canaan
Publikováno v:
Photochemotherapy: Photodynamic Therapy and Other Modalities III.
Benzoporphyrin derivative monoacid ring A [BPD-MA (verteporfin) or BPD], a second generation photosensitizer tested in clinical trials in combination with red light was compared for its PDT efficiency in vitro and in vivo upon activation with light i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2dcf253a216a2d0711d2d0a75932a45
https://doi.org/10.1117/12.297797
https://doi.org/10.1117/12.297797
Publikováno v:
SPIE Proceedings.
Skin photosensitivity is the most common side effect of photodynamic therapy (PDT) and in clinical situations needs to be avoided or at least minimized. However, because of the accessibility of skin tissue, skin photosensitivity represents a useful t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fe0fceebae659f6c4deb76197d622e8
https://doi.org/10.1117/12.230986
https://doi.org/10.1117/12.230986
Publikováno v:
Proceedings of SPIE.
Uptake and release/retention of the photosensitizer, benzoporphyrin derivative, monoacid ring A (BPD; 1 - 20 (mu) g/mL) was studied using cell lines (K562, L1210) and normal, non- activated and Concanavalin A-activated murine splenocytes. Concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26aa7f9afa0e2a4b4eabbabf8adfa24e
https://doi.org/10.1117/12.199144
https://doi.org/10.1117/12.199144
Autor:
R. K. Chowdhary, Meadows Howard E, Alice J. Canaan, Douglas Waterfield, Anna M. Richter, Julia G. Levy, Ashok K. Jain, Leslie G. Ratkay, Modestus Obochi
Publikováno v:
SPIE Proceedings.
Benzoporphyrin derivative monoacid ring A (BPD) is taken up rapidly (within 30 minutes) by most cells. Rapidly dividing tumor cell lines and mitogen activated murine T lymphocytes were found to take up significantly more (5 - 10 fold) BPD than do nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4864c134f2c38a89d3c5beeb7812ea6
https://doi.org/10.1117/12.168666
https://doi.org/10.1117/12.168666
Autor:
Modestus Obochi, Alice J. Canaan, Julia G. Levy, Meadows Howard E, Anna M. Richter, Ashok K. Jain
Publikováno v:
Photochemistry and photobiology. 59(3)
In vitro experiments with benzoporphyrin derivative monoacid ring A (BPD) confirmed earlier studies that it was taken up rapidly (within 30 min) to maximum concentrations by all cells tested. It was also confirmed that rapidly dividing tumor cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce2e34d1ee9e94c1873ec17e6ef5594
https://pubmed.ncbi.nlm.nih.gov/8016215
https://pubmed.ncbi.nlm.nih.gov/8016215