Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alice Hlobilkova"'
Autor:
Jan Bouchal, Katerina Bouchalova, Gvantsa Kharaishvili, Jana Vrbkova, Magdalena Megova, Alice Hlobilkova
Publikováno v:
ResearcherID
Background: Breast cancer (BC), the most frequent malignancy in women worldwide, is currently diagnosed in about 1.4 million female patients annually. Approximately 10-20% of BC is represented by triple negative breast cancer (TNBC) which is aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084d3453881bde2bff390f7504ae119f
https://doi.org/10.2174/1389450115666141106151143
https://doi.org/10.2174/1389450115666141106151143
Autor:
Hans Skovgaard Poulsen, Jiri Bartek, Helle Broholm, Ondrej Kalita, Petra Hamerlik, Jiri Ehrmann, Jiri Lukas, Alice Hlobilkova, Marie-Thérése Stockhausen, Laursen H, Zdenek Kolar, J Bartkova
Publikováno v:
Oncogene. 29:5095-5102
Malignant gliomas, the deadliest of brain neoplasms, show rampant genetic instability and resistance to genotoxic therapies, implicating potentially aberrant DNA damage response (DDR) in glioma pathogenesis and treatment failure. Here, we report on g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cd6dda52d3b31e5a54fab8a8563a20
https://doi.org/10.1038/onc.2010.249
https://doi.org/10.1038/onc.2010.249
Publikováno v:
Biomedical Papers. 147:11-17
The molecular basis for the transition of carcinoma of the prostate from androgen-dependent to androgen-independent growth is largely unknown. Currently for example, it is not clear whether the androgen-independent phenotype is a result of selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a042d9ce88d803052276d553f1ee90
https://doi.org/10.5507/bp.2003.002
https://doi.org/10.5507/bp.2003.002
Autor:
Marian Hajduch, Shantha Perera, Paul Murray, Miroslav Strnad, Mad'arová J, Vojtesek B, Lukesová M, Alice Hlobilkova, Zdenek Kolar, René Lenobel
Publikováno v:
Molecular Pathology. 55:227-234
Aims: Because of the high prevalence of prostatic cancer and the limitations of its treatment, enormous effort has been put into the development of new therapeutic modalities. One potential tool is the use of cyclin dependent kinase (CDK) inhibitors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a5d8a577863bf22db0aa2bb70bc51e
https://doi.org/10.1136/mp.55.4.227
https://doi.org/10.1136/mp.55.4.227
Publikováno v:
Biochemical Pharmacology. 63:1177-1181
The effects of the 17beta-estradiol, dihydrotestosterone and hormone antagonists tamoxifen and bicalutamide on telomerase activity and expression of cell cycle related proteins in the androgen-sensitive prostatic cancer cell line LNCaP were studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ab34bfa6c7a13215c7ab24439badfe
https://doi.org/10.1016/s0006-2952(01)00927-3
https://doi.org/10.1016/s0006-2952(01)00927-3
Autor:
Rudolf Nenutil, Paul Murray, B Vojtĕsek, D Cernochová, Zdenek Kolar, E Pospísilová, V Lichnovský, Alice Hlobilkova
Publikováno v:
Molecular Pathology. 51:131-137
AIMS: To study the patterns of p53 and Bcl-2 expression in relation to cell proliferation during human embryogenesis in order to help elucidate their potential roles in the regulation of cell proliferation and apoptosis during morphogenesis. METHODS:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e94a194886092f770249475119d025
https://doi.org/10.1136/mp.51.3.131
https://doi.org/10.1136/mp.51.3.131
Publikováno v:
Neoplasma. 56(4)
Astrocytomas, particularly high grade astrocytoma, are brain tumors with potent angiogenic activity. Our immnunohistochemical study assessed vascular endothelial growth factor (VEGF), VEGF receptors (Flk-1, and Flt-1), the intermediate filamental pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4712e5620aba4c1945450689a1f5308b
https://pubmed.ncbi.nlm.nih.gov/19473053
https://pubmed.ncbi.nlm.nih.gov/19473053
Autor:
Petra Knizetova, Iveta Vancova, Ondrej Kalita, Alice Hlobilkova, Jiri Bartek, Jiri Ehrmann, Zdenek Kolar
Publikováno v:
Cell cycle (Georgetown, Tex.). 7(16)
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis and progression of malignant brain tumors. Given the significance of tumor microenvironment in general, and the established role of paracrine VEGF signaling in glioblastom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89fd7d81e52eadeaa28515392e32bfd
https://pubmed.ncbi.nlm.nih.gov/18719373
https://pubmed.ncbi.nlm.nih.gov/18719373
Autor:
Zdenek Kolar, Svetlana Brychtova, Renata Kučerová Ph.D, Martina Bienová Ph.D, Eva Sedlakova, Veronika Krejci, Michala Bezdekova, Alice Hlobilkova, Jana Steigerova, Tomas Brychta
Publikováno v:
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 151(2)
Background Trichofolliculomas and trichoepitheliomas are benign skin neoplasms originating from hair follicle cells. They result from defects in the signaling pathways that regulate hair follicle morphogenesis and regeneration. Thus they seem to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34569f77184e82bfe6927df0f258f2d0
https://pubmed.ncbi.nlm.nih.gov/18345259
https://pubmed.ncbi.nlm.nih.gov/18345259
Autor:
Marian Hajduch, Ondrej Kalita, Michael Houdek, Miroslav Kala, Hana Svebisova, Alice Hlobilkova, Jiri Ehrmann, Radek Trojanec
Publikováno v:
Journal of neuro-oncology. 88(2)
An intratumoral or peritumoral microbial intracranial abscess is an infrequent diagnosis. The development of this complication may not be preceded by apparent local or general infection in all cases. To identify this diagnosis by radiological (MRI) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be694c1b86c63d9096ccdd8a5dc5de1
https://pubmed.ncbi.nlm.nih.gov/18317688
https://pubmed.ncbi.nlm.nih.gov/18317688