Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Alice Hervieu"'
Autor:
Nicolas Roussot, Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Alice Hervieu, Audrey Hennequin, Sylvie Zanetta, Lorraine Dalens, Théo Fourrier, Loick Galland, Pierre Jacob, Aurélie Bertaut, Emilie Rederstorff, Cédric Chevalier, Sarah Ghirardi, Elodie Gilbert, Azzat Khoukaz, Etienne Martin, Constance Nicolet, Magali Quivrin, David Thibouw, Noémie Vulquin, Gilles Truc, Magali Rouffiac, Francois Ghiringhelli, Céline Mirjolet
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Immunotherapy targeting the PD-1/PD-L1 pathway is a standard of care in a number of metastatic malignancies, but less than a fifth of patients are expected to respond to ICIs (Immune Checkpoint Inhibitors). In a clinical trial, co
Externí odkaz:
https://doaj.org/article/a9a844b15014448f8d6e92baf2f9b80d
Autor:
François Skowron, Stéphane Mouret, Arnaud Seigneurin, Henri Montaudié, Eve Maubec, Florent Grange, Gaelle Quereux, Philippe Célérier, Mona Amini‐Adle, Sophie Dalac‐Rat, Julie De Quatrebarbes, Ouidad Zehou, Abed Safia, Philippe Muller, Philippe Modiano, Laurent Misery, Noemie Litrowski, Florence Brunet‐Possenti, Laurent Mortier, Guido Bens, Alice Hervieu, Nicolas Leduc, Thomas Jouary, Candice Lesage, Nathalie Beneton, Yannick Le Corre, Lionnel Geoffrois, Domitille Thomas‐Beaulieu, Ewa Hainaut, Marie‐Thérèse Leccia
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 638-642 (2023)
Externí odkaz:
https://doaj.org/article/ea8ac9a2758d4c07a6dd91cc17cbe831
Autor:
Lionnel Geoffrois, Alexandre Harlé, Nassim Sahki, Aleksandra Sikanja, Florence Granel-Brocard, Alice Hervieu, Laurent Mortier, Géraldine Jeudy, Catherine Michel, Charlée Nardin, Cécile Huin-Schohn, Jean-Louis Merlin
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background With more than 15,000 new cases /year in France and 2,000 deaths, cutaneous melanoma represents approximately 4% of incidental cancers and 1.2% of cancer related deaths. In locally advanced (stage III) or resectable metastatic (st
Externí odkaz:
https://doaj.org/article/e9e8f4b43a4c4f71addb8481df90fdbe
Autor:
Agostina Stradella, Francois Ghiringhelli, Ana Maia, Macarena Gonzalez, Cécile Gouttefangeas, Ulrich Herrlinger, David Reardon, Ahmed Idbaih, Patrick Wen, Ghazaleh Tabatabai, Wolfgang Wick, Mirjam Renovanz, Maria Vieito Villar, Christophe Bonny, Joao Gamelas Magalhaes, Hélène Toussaint, Jean-Michel Paillarse, Marta GilMartin, Iris Mildenberger, Michael C Burger, Alice Hervieu, Mehdi Touat, Antje Wick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b66bf531835946ef99e16b169d7cc47a
Autor:
Gaëtan Chanteloup, Marine Cordonnier, Nicolas Isambert, Aurélie Bertaut, Alice Hervieu, Audrey Hennequin, Maxime Luu, Sylvie Zanetta, Bruno Coudert, Leila Bengrine, Isabelle Desmoulins, Laure Favier, Aurélie Lagrange, Pierre-Benoit Pages, Ivan Gutierrez, Jeanine Lherminier, Laure Avoscan, Clémentine Jankowski, Cédric Rébé, Angélique Chevriaux, Marie-Martine Padeano, Charles Coutant, Sylvain Ladoire, Sylvain Causeret, Laurent Arnould, Céline Charon-Barra, Vanessa Cottet, Julie Blanc, Christine Binquet, Marc Bardou, Carmen Garrido, Jessica Gobbo
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Exosomes are nanovesicles released by all cells that can be found in the blood. A key point for their use as potential biomarkers in cancer is to differentiate tumour-derived exosomes from other circulating nanovesicles. Heat shock protein-70 (HSP70)
Externí odkaz:
https://doaj.org/article/c85f810717b149b5b53bf842e7b16c75
Autor:
Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot, Jean David Fumet, Julie Blanc, Caroline Truntzer, Isabelle Desmoulins, Sylvain Ladoire, Audrey Hennequin, Laure Favier, Leila Bengrine, Julie Vincent, Alice Hervieu, Jean-Florian Guion Dusserre, Come Lepage, Pascal Foucher, Christophe Borg, Juliette Albuisson, Laurent Arnould, Sophie Nambot, Laurence Faivre, Romain Boidot, Francois Ghiringhelli
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analy
Externí odkaz:
https://doaj.org/article/e28bb1596617481991af99f2ee075d39
Autor:
Hélène Bellio, Aurélie Bertaut, Alice Hervieu, Sylvie Zanetta, Audrey Hennequin, Julie Vincent, Rémi Palmier, Leila Bengrine-Lefevre, François Ghiringhelli, Jean-David Fumet
Publikováno v:
Cancers, Vol 13, Iss 21, p 5472 (2021)
The care of metastatic colorectal cancers is based on combination chemotherapies including 5-fluorouracil, oxaliplatin, irinotecan, and monoclonal antibodies targeting the epidermal growth factor receptor or vascular endothelial growth factor. The re
Externí odkaz:
https://doaj.org/article/8925284c64c64aa89355bb16026e4137
Autor:
Nicolas Isambert, Alice Hervieu, Cedric Rébé, Audrey Hennequin, Christophe Borg, Sylvie Zanetta, Angélique Chevriaux, Corentin Richard, Valentin Derangère, Emeric Limagne, Julie Blanc, Aurélie Bertaut, François Ghiringhelli
Publikováno v:
OncoImmunology, Vol 7, Iss 9 (2018)
In preclinical models, IL-1β inhibition could enhance the efficacy of fluorouracil (5-FU). In this phase 2 study, we assessed the activity and safety of 5-FU plus bevacizumab and anakinra (an IL-1β and α inhibitor) in patients with metastatic colo
Externí odkaz:
https://doaj.org/article/7101ec3870244562a55a18d1cdcd1e75
Autor:
Grégoire Mignot, Alice Hervieu, Pierre Vabres, Sophie Dalac, Geraldine Jeudy, Blandine Bel, Lionel Apetoh, François Ghiringhelli
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105907 (2014)
BackgroundThe importance of immune responses in the control of melanoma growth is well known. However, the implication of these antitumor immune responses in the efficacy of dacarbazine, a cytotoxic drug classically used in the treatment of melanoma,
Externí odkaz:
https://doaj.org/article/6081e4e3111d4195adcb82f9d1b529b5
Autor:
Jordi Rodón, Pauline Funchain, Theodore W Laetsch, Hendrik-Tobias Arkenau, Alice Hervieu, Christian F Singer, Yonina R Murciano-Goroff, Sant P Chawla, Kristin Anthony, Ikuo Yamamiya, Mei Liu, Abdel-Baset Halim, Karim A Benhadji, Osamu Takahashi, Suzette Delaloge
Publikováno v:
Future Oncology. 18:3377-3387
PTEN acts as a potent tumor suppressor within the PI3K/AKT/mTOR pathway. Germline mutations in the PTEN gene are a hallmark of PTEN hamartoma tumor syndrome, which includes Cowden syndrome, where they appear to elevate lifetime risk of cancer. Target