Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Alice Gilman‐Sachs"'
Autor:
Arpita Kulshrestha, Gajendra K. Katara, Safaa A. Ibrahim, Valerie E. Riehl, Sylvia Schneiderman, Mahmood Bilal, Alexandria N. Young, Shayna Levine, Sara Fleetwood, James Dolan, Alice Gilman‐Sachs, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2436-2454 (2020)
Tumor acidity is the key metabolic feature promoting cancer progression and is modulated by pH regulators on a cancer cell's surface that pump out excess protons/lactic acid for cancer cell survival. Neutralizing tumor acidity improves the therapeuti
Externí odkaz:
https://doaj.org/article/a303e506c5224df1b905decf62dbe935
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
During pregnancy, various immune effectors and molecules participating in the immune-microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus. Activated maternal immune effectors by the trophoblast antigens, such as T h
Externí odkaz:
https://doaj.org/article/82e200ae6bee4823bfc1ab3475d7f948
Autor:
Gajendra K. Katara, Arpita Kulshrestha, Liqun Mao, Xin Wang, Manoranjan Sahoo, Safaa Ibrahim, Sahithi Pamarthy, Kimiko Suzue, Gajendra S. Shekhawat, Alice Gilman‐Sachs, Kenneth D. Beaman
Publikováno v:
Molecular Oncology, Vol 12, Iss 2, Pp 208-223 (2018)
Extracellular matrix (ECM) critically impacts tumor progression and is influenced by both cancer and host tissue cells. While our understanding of cancer cell ECM remodeling is widespread, the importance of host tissue ECM, which provides initial con
Externí odkaz:
https://doaj.org/article/2fdedb0d0eda42da86f73dcf151f541e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Iodine is an essential element required for the function of all organ systems. Although the importance of iodine in thyroid hormone synthesis and reproduction is well known, its direct effects on the immune system are elusive. Human leukocytes expres
Externí odkaz:
https://doaj.org/article/fc330d768ad6401a968fc3d30dfa964b
Autor:
Renukadevi Patil, Arpita Kulshrestha, Anjali Tikoo, Sara Fleetwood, Gajendra Katara, Bala Kolli, William Seibel, Alice Gilman-Sachs, Shivaputra A. Patil, Kenneth D. Beaman
Publikováno v:
Molecules, Vol 22, Iss 9, p 1559 (2017)
The vacuolar (H+)-ATPases (V-ATPases) are a family of ATP-driven proton pumps and they have been associated with cancer invasion, metastasis, and drug resistance. Despite the clear involvement of V-ATPases in cancer, the therapeutic use of V-ATPase-t
Externí odkaz:
https://doaj.org/article/5d7b76bddab94dc49d20acdc1dd62c09
Autor:
Kuniaki Ota, Mukesh Kumar Jaiswal, Sivakumar Ramu, Rajasinjham Jeyendran, Joanne Kwak-Kim, Alice Gilman-Sachs, Kenneth D Beaman
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70470 (2013)
BACKGROUND:A number of laboratory tests have been developed to determine properties of spermatozoa quality but few have been adopted into routine clinical use in place of the WHO semen analysis. We investigated whether Atp6v0a2 (a2 isoform of vacuola
Externí odkaz:
https://doaj.org/article/d129591950d24dc5ae35e4fd1ff06429
Autor:
Joanne Kwak-Kim, Lujain AlSubki, Thanh Luu, Umida Ganieva, Amy Thees, Svetlana Dambaeva, Alice Gilman-Sachs
Publikováno v:
Fertility and Sterility. 117:1132-1143
Unexplained subfertility and implantation failures not only are emotionally and physically distressing but also become a significant obstacle to reproductive-age couples who wish to build their family. Often, the currently recommended evaluation for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c429d84e697d38807830fe16714e7572
https://doi.org/10.1016/j.fertnstert.2022.04.009
https://doi.org/10.1016/j.fertnstert.2022.04.009
Autor:
Sarah Mustaly-Kalimi, Wacey Gallegos, Robert A. Marr, Alice Gilman-Sachs, Daniel A. Peterson, Israel Sekler, Grace E. Stutzmann
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(49)
Impairments in neural lysosomal- and autophagic-mediated degradation of cellular debris contribute to neuritic dystrophy and synaptic loss. While these are well-characterized features of neurodegenerative disorders such as Alzheimer’s disease (AD),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2e635676abe3f490c5258ba4face71
https://pubmed.ncbi.nlm.nih.gov/36442130
https://pubmed.ncbi.nlm.nih.gov/36442130
Autor:
Valerie Riehl, Sylvia Schneiderman, Shayna Levine, Alexandria N. Young, Safaa A. Ibrahim, James Dolan, Arpita Kulshrestha, Mahmood Bilal, Kenneth D. Beaman, Sara Fleetwood, Gajendra K. Katara, Alice Gilman-Sachs
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 10, Pp 2436-2454 (2020)
Molecular Oncology, Vol 14, Iss 10, Pp 2436-2454 (2020)
Tumor acidity is the key metabolic feature promoting cancer progression by eliciting immune‐suppression. V‐ATPases on a cancer cell's surface pump out excess protons and acidify the tumor microenvironment (TME). In vivo treatment of ovarian tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0923bfdecac6564a54c9ceac6bba8ae
https://doi.org/10.1002/1878-0261.12782
https://doi.org/10.1002/1878-0261.12782
