Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alice G Sorgo"'
Autor:
Christoph Ruckenstuhl, Christine Netzberger, Iryna Entfellner, Didac Carmona-Gutierrez, Thomas Kickenweiz, Slaven Stekovic, Christina Gleixner, Christian Schmid, Lisa Klug, Alice G Sorgo, Tobias Eisenberg, Sabrina Büttner, Guillermo Mariño, Rafal Koziel, Pidder Jansen-Dürr, Kai-Uwe Fröhlich, Guido Kroemer, Frank Madeo
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004347 (2014)
Reduced supply of the amino acid methionine increases longevity across species through an as yet elusive mechanism. Here, we report that methionine restriction (MetR) extends yeast chronological lifespan in an autophagy-dependent manner. Single delet
Externí odkaz:
https://doaj.org/article/2513812671d248ae85a0d77c88148d65
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003050 (2012)
Externí odkaz:
https://doaj.org/article/f1c4e6eb95d844ce8898e56da5febe02
Publikováno v:
Microbiology-SGM, 159(8), 1673-1682. Society for General Microbiology
The opportunistic fungal pathogen Candida albicans has developed various ways to overcome iron restriction in a mammalian host. Using different surface proteins, among them membrane- and wall-localized glycosylphosphatidylinositol (GPI) proteins, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f3d38d8a7872f5a4c78f512d167fa2
https://hdl.handle.net/11245/1.395900
https://hdl.handle.net/11245/1.395900
Autor:
Iuliana V. Ene, Clemens J. Heilmann, Chris G. de Koster, Alice G. Sorgo, Frans M. Klis, Carol A. Munro, Alistair J. P. Brown, Louise A. Walker
Publikováno v:
Proteomics
PROTEOMICS, 12(21), 3164-3179. Wiley-VCH Verlag
PROTEOMICS
PROTEOMICS, 12(21), 3164-3179. Wiley-VCH Verlag
PROTEOMICS
The major fungal pathogen Candida albicans can occupy diverse microenvironments in its human host. During colonization of the gastrointestinal or urogenital tracts, mucosal surfaces, bloodstream, and internal organs, C. albicans thrives in niches tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185c46809cf5a743fa0d8252589e9034
http://europepmc.org/articles/PMC3569869
http://europepmc.org/articles/PMC3569869
Autor:
Pidder Jansen-Dürr, Frank Madeo, Thomas R. Pieber, Guillermo Mariño, Rafal Koziel, Tobias Eisenberg, Iryna Entfellner, Ivan Hajnal, Slaven Stekovic, Frank Sinner, Christoph Ruckenstuhl, Christine Netzberger, Guido Kroemer, Lisa Klug, Alice G. Sorgo, Christina Gleixner, Didac Carmona-Gutierrez, Sabrina Büttner, Kai-Uwe Fröhlich, Christian Schmid, Thomas Kickenweiz, Christoph Magnes
Publikováno v:
Microbial Cell, Vol 1, Iss 5, Pp 160-162 (2014)
Methionine restriction (MetR) is one of the rare regimes that prolongs lifespan across species barriers. Using a yeast model, we recently demonstrated that this lifespan extension is promoted by autophagy, which in turn requires vacuolar acidificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c76c69ae1f62eeb7c34c9f9f329331e
http://microbialcell.com/researcharticles/autophagy-extends-lifespan-via-vacuolar-acidification/
http://microbialcell.com/researcharticles/autophagy-extends-lifespan-via-vacuolar-acidification/
Autor:
Dorthe Rippert, Katja Backhaus, Alice G. Sorgo, Frans M. Klis, Jürgen J. Heinisch, Clemens J. Heilmann, Chris G. de Koster, Rosaura Rodicio
Publikováno v:
European Journal of Cell Biology, 92(12), 383-395. Urban und Fischer Verlag GmbH und Co. KG
The trimeric SNF1 complex from Saccharomyces cerevisiae, a homolog of mammalian AMP-activated kinase, has been primarily implicated in signaling for the utilization of alternative carbon sources to glucose. We here find that snf1 deletion mutants are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5978190895b2ca65acdec7fcc5d25797
https://pubmed.ncbi.nlm.nih.gov/24486034
https://pubmed.ncbi.nlm.nih.gov/24486034
Publikováno v:
FEMS Microbiology Letters, 338(1), 10-17. Oxford University Press
The opportunistic fungal pathogen Candida albicans occupies various niches of the human body such as the skin and the mucosal surfaces of the gastrointestinal and urogenital tracts. It can also enter the blood stream and cause deadly, systemic infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df738cf477a8eabcc4b9438847ca16aa
https://dare.uva.nl/personal/pure/en/publications/beyond-the-wall-candida-albicans-secretes-to-survive(3e27fdfe-d95a-4924-a060-19f3ceb427c8).html
https://dare.uva.nl/personal/pure/en/publications/beyond-the-wall-candida-albicans-secretes-to-survive(3e27fdfe-d95a-4924-a060-19f3ceb427c8).html
Autor:
Paul H. Atkinson, Greta Moraes, Bede P. Busby, Rosemary W. Heathcott, Stephan Andreas Angermayr, David S. Bellows, Dora C. Leahy, James H. Matthews, Kristina Boeger, Alice G. Sorgo, Peter T. Northcote, Jacqueline M. Barber, Ploi Yibmantasiri
Publikováno v:
Molecular bioSystems. 8(3)
Neothyonidioside is a triterpene glycoside (TG) isolated from the sea cucumber, Australostichopus mollis, that is potently cytotoxic to S. cerevisiae, but does not permeabilize cellular membranes. We mutagenized S. cerevisiae and isolated a neothioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c76bdbc1c8ab84f83bfdb1f072325a
https://pubmed.ncbi.nlm.nih.gov/22271309
https://pubmed.ncbi.nlm.nih.gov/22271309
Autor:
Henk L. Dekker, Chris G. de Koster, Alice G. Sorgo, Adriaan R. Siliakus, Leo J. de Koning, Stanley Brul, Clemens J. Heilmann, Frans M. Klis
Publikováno v:
Microbiology-SGM, 157(8), 2297-2307. Society for General Microbiology
The ability ofCandida albicansto switch from yeast to hyphal growth is essential for its virulence. The walls and especially the covalently attached wall proteins are involved in the primary host–pathogen interactions. Three hyphal induction method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7288390d068e83da03619e7efb871e9a
https://pubmed.ncbi.nlm.nih.gov/21602216
https://pubmed.ncbi.nlm.nih.gov/21602216
Autor:
Stanley Brul, Clemens J. Heilmann, Henk L. Dekker, Martijn Bekker, Alice G. Sorgo, Chris G. de Koster, Leo J. de Koning, Frans M. Klis
Publikováno v:
Eukaryotic Cell, 10(8), 1071-1081. American Society for Microbiology
Fluconazole is a commonly used antifungal drug that inhibits Erg11, a protein responsible for 14α-demethylation during ergosterol synthesis. Consequently, ergosterol is depleted from cellular membranes and replaced by toxic 14α-methylated sterols,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664d5167e95272911cf3cb5a1b6bf3a1
https://dare.uva.nl/personal/pure/en/publications/effects-of-fluconazole-on-the-secretome-the-wall-proteome-and-wall-integrity-of-the-clinical-fungus-candida-albicans(cd909d0c-55a5-4c08-8952-0cf6d3af302e).html
https://dare.uva.nl/personal/pure/en/publications/effects-of-fluconazole-on-the-secretome-the-wall-proteome-and-wall-integrity-of-the-clinical-fungus-candida-albicans(cd909d0c-55a5-4c08-8952-0cf6d3af302e).html