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pro vyhledávání: '"Alice E Solomon"'
Publikováno v:
Circulation Research. 129
Cardiovascular disease (CVD) is the leading cause of death in women worldwide. Menopause is associated with increased susceptibility to CVD, but the mechanism is currently unknown. Studies have suggested that loss of estrogen signaling in the intesti
Autor:
Alice E Solomon, Christina Hoyer-Kimura, Victoria Salcedo, Christian Leber, Joshua P Fricks, Brij Kathuria, John P. Konhilas, Frank A. Duca
Publikováno v:
Circulation Research. 129
The average woman spends over 40% of their life in menopause, during which estrogen’s protective roles are lost and women suffer an increased risk of developing inflammatory pathologies including obesity and worsened cardiovascular disease outcomes
Autor:
Anu Toropainen, Anna Eshghi, Michael B. Whalen, Casey E. Romanoski, Kadri Õunap, Maykel López Rodríguez, Lindsey K. Stolze, Ilakya Selvarajan, Tiit Örd, Minna U. Kaikkonen, Jin Li, Austin C. Conklin, Alice E Solomon, Yun Fang
Publikováno v:
Am J Hum Genet
The American Journal of Human Genetics
The American Journal of Human Genetics
The identification of causal variants and mechanisms underlying complex disease traits in humans is important for the progress of human disease genetics; this requires finding strategies to detect functional regulatory variants in disease-relevant ce