Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Alice E Denton"'
Autor:
Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184732 (2017)
TNF is a pro-inflammatory cytokine produced by both lymphoid and non-lymphoid cells. As a consequence of the widespread expression of its receptors (TNFR1 and 2), TNF plays a role in many important biological processes. In the context of influenza A
Externí odkaz:
https://doaj.org/article/260e87aec1f54e8a977e6b7d40d0d4ff
Autor:
Michelle A Linterman, Alice E Denton, Devina P Divekar, Ilona Zvetkova, Leanne Kane, Cristina Ferreira, Marc Veldhoen, Simon Clare, Gordon Dougan, Marion Espéli, Kenneth GC Smith
Publikováno v:
eLife, Vol 3 (2014)
The co-stimulatory molecule CD28 is essential for activation of helper T cells. Despite this critical role, it is not known whether CD28 has functions in maintaining T cell responses following activation. To determine the role for CD28 after T cell p
Externí odkaz:
https://doaj.org/article/3e6354d1e25049648fe723c0c68f3d2a
Autor:
Stephen J Turner, Brendan E Russ, Alice E Denton, Lauren eHatton, Hayley eCroom, Matthew R Olson
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
A cardinal feature of adaptive, cytotoxic T lymphocyte (CTL)-mediated immunity is the ability of naïve CTLs to undergo a program of differentiation and proliferation upon activation resulting in the acquisition of lineage-specific T cell functions a
Externí odkaz:
https://doaj.org/article/6cc19abd9eb14033b09bac58fad3e682
Autor:
Alyssa Silva-Cayetano, Sigrid Fra-Bido, Philippe A. Robert, Silvia Innocentin, Alice R. Burton, Emily M. Watson, Jia Le Lee, Louise M. C. Webb, William S. Foster, Ross C. J. McKenzie, Alexandre Bignon, Ine Vanderleyden, Dominik Alterauge, Julia P. Lemos, Edward J. Carr, Danika L. Hill, Isabella Cinti, Karl Balabanian, Dirk Baumjohann, Marion Espeli, Michael Meyer-Hermann, Alice E. Denton, Michelle A. Linterman
The magnitude and quality of the germinal center (GC) response decline with age, resulting in poor vaccine-induced immunity in older individuals. A functional GC requires the co-ordination of multiple cell types across time and space, in particular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6af918521eb723049f1db70982a5b74
http://hdl.handle.net/10044/1/104428
http://hdl.handle.net/10044/1/104428
Autor:
Kevin M. Brindle, De-en Hu, Bangwen Xie, Susana Ros, Maria Fala, Marcel Gehrung, Robert Bielik, Jodi L. Miller, Richard Grenfell, Alice E. Denton, David Y. Lewis, Alan J. Wright, Jiazheng Wang, Richard L. Hesketh
Figure S1. Timeline of injections and imaging for the main treatment-response study. Figure S2. Tumor volume measurements for (a) Colo205 and (b) MDA-MB-231 tumors (b & e) before and (c & f) 24 h after MEDI3039 treatment. Figure S3. Confirmation that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3b60699edcbecd2baebeb7e39e4103
https://doi.org/10.1158/0008-5472.22421690
https://doi.org/10.1158/0008-5472.22421690
Autor:
Kevin M. Brindle, De-en Hu, Bangwen Xie, Susana Ros, Maria Fala, Marcel Gehrung, Robert Bielik, Jodi L. Miller, Richard Grenfell, Alice E. Denton, David Y. Lewis, Alan J. Wright, Jiazheng Wang, Richard L. Hesketh
Metabolic imaging has been widely used to measure the early responses of tumors to treatment. Here, we assess the abilities of PET measurement of [18F]FDG uptake and MRI measurement of hyperpolarized [1-13C]pyruvate metabolism to detect early changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d90398ee5ef0e4ba50d19373ff25110
https://doi.org/10.1158/0008-5472.c.6510989.v1
https://doi.org/10.1158/0008-5472.c.6510989.v1
Autor:
Joshua D'Rozario, Konstantin Knoblich, Mechthild Lütge, Christian Pérez Shibayama, Hung‐Wei Cheng, Yannick O. Alexandre, David Roberts, Joana Campos, Emma Dutton, Muath Suliman, Alice E. Denton, Shannon J. Turley, Richard L. Boyd, Scott N. Mueller, Burkhard Ludewig, Tracy S.P. Heng, Anne L. Fletcher
Publikováno v:
European Journal of Immunology.
Autor:
Alice E. Denton, James Dooley, Isabella Cinti, Alyssa Silva-Cayetano, Sigrid Fra-Bido, Silvia Innocentin, Danika L. Hill, Edward J. Carr, Andrew N.J. McKenzie, Adrian Liston, Michelle A. Linterman
Publikováno v:
Sci Immunol
The failure to generate enduring humoral immunity after vaccination is a hallmark of advancing age. This can be attributed to a reduction in the germinal center (GC) response, which generates long-lived antibody-secreting cells that protect against (
Autor:
Alice E Denton, Michelle A. Linterman
Publikováno v:
Nature Immunology. 22:1074-1076
Inhibition of ferroptosis via selenium supplementation promotes the survival of follicular helper T cells, boosting the germinal center and antibody response following vaccination in mice and people.
Autor:
Nicola Evans-Bailey, Marisa Stebegg, Ine Vanderleyden, Sigrid Fra-Bido, Michelle A. Linterman, Silvia Innocentin, Wim Pierson, Alice E. Denton, Hanneke Okkenhaug
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 611-619.e4 (2020)
Cell Reports
619.e4
Cell Reports
619.e4
Summary The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to require follicular regulatory T (