Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alice C. N. Brown"'
Autor:
Alice C. N. Brown, Stephane Oddos, Ian M. Dobbie, Juha-Matti Alakoskela, Richard M. Parton, Philipp Eissmann, Mark A. A. Neil, Christopher Dunsby, Paul M. W. French, Ilan Davis, Daniel M. Davis
Publikováno v:
PLoS Biology, Vol 10, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/217077cea1f44f1ab4c2c0c7d74b8c48
Autor:
Nalini Marino, Sam Illingworth, Prithvi Kodialbail, Ashvin Patel, Hugo Calderon, Rochelle Lear, Kerry D Fisher, Brian R Champion, Alice C N Brown
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177810 (2017)
Oncolytic viruses which infect and kill tumour cells can also be genetically modified to express therapeutic genes that augment their anti-cancer activities. Modifying oncolytic viruses to produce effective cancer therapies is challenging as encoding
Externí odkaz:
https://doaj.org/article/91f88a97391341e4b1e62c1a9d9294db
Autor:
Alice C. N. Brown, Daniel M. Davis, Paul M. W. French, Alexander Savell, Martin O. Lenz, Hugo G. Sinclair, Christopher Dunsby, Mark A. A. Neil, James H. Clegg
Publikováno v:
Journal of Biophotonics. 7:29-36
We present a stimulated emission depletion (STED) microscope that provides 3-D super resolution by simultaneous depletion using beams with both a helical phase profile for enhanced lateral resolution and an annular phase profile to enhance axial reso
Natural killer (NK) cells secrete lytic granules to directly kill virus-infected or transformed cells and secrete cytokines to communicate with other cells. Three-dimensional super-resolved images of F-actin, lytic granules, and IFN-γ in primary hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d66a5a35a0ec7d958e105660a986af
https://ora.ox.ac.uk/objects/uuid:3208e9e8-2feb-4b8d-85e1-e059b7d7297e
https://ora.ox.ac.uk/objects/uuid:3208e9e8-2feb-4b8d-85e1-e059b7d7297e
Autor:
Valentin Grabovsky, Memet Aker, Ofer Mandelboim, Ronen Alon, Daniel M. Davis, Sa'ar Mizrahi, Raizy Gruda, Sara W. Feigelson, Hagit Achdout, Yotam Bar-On, Chamutal Gur, Alice C. N. Brown
Publikováno v:
Blood. 120:3915-3924
Recent evidence suggests that kindlin-3 is a major coactivator, required for most, if not all, integrin activities. Here we studied the function of kindlin-3 in regulating NK cell activation by studying a patient with kindlin-3 deficiency (leukocyte
Autor:
Alison Best, Thomas F. Hiemstra, Alice C. N. Brown, Fiona E. Karet, Shoko Horita, Ya Su, Aiwu Zhou, Ashley M. Toye, Andrew C. Fry, Katherine G. Blake-Palmer
Publikováno v:
American Journal of Physiology-Renal Physiology
The mammalian kidney isoform of the essential chloride-bicarbonate exchanger AE1 differs from its erythrocyte counterpart, being shorter at its N terminus. It has previously been reported that the glycolytic enzyme GAPDH interacts only with erythrocy
Autor:
Alice C. N. Brown, Stephane Oddos, Ian M. Dobbie, Juha-Matti Alakoskela, Richard M. Parton, Philipp Eissmann, Mark A. A. Neil, Christopher Dunsby, Paul M. W. French, Ilan Davis, Daniel M. Davis
Publikováno v:
PLoS Biology
PLoS Biology, Vol 10, Iss 8 (2012)
PLoS Biology, Vol 10, Iss 8 (2012)
Autor:
Mark A. A. Neil, Paul M. W. French, Philipp Eissmann, Daniel M. Davis, Christopher Dunsby, Juha-Matti Alakoskela, Ilan Davis, Ian M. Dobbie, Stephane Oddos, Alice C. N. Brown, Richard M. Parton
Publikováno v:
PLoS Biology, Vol 9, Iss 9, p e1001152 (2011)
PLoS Biology
PLoS Biology
Super-resolution 3D imaging reveals remodeling of the cortical actin meshwork at the natural killer cell immune synapse, which is likely to be important for secretion of lytic granules.
Natural Killer (NK) cells are innate immune cells that secr
Natural Killer (NK) cells are innate immune cells that secr
Autor:
Paul M. W. French, Mark A. A. Neil, Daniel M. Davis, Egidijus Auksorius, Christopher Dunsby, Martin O. Lenz, Alice C. N. Brown
Publikováno v:
SPIE Proceedings.
We present a stimulated emission depletion (STED) fluorescence lifetime imaging (FLIM) microscope, excited by a microstructured optical fibre supercontinuum source that is pumped by a femtosecond Ti:Sapphire-laser, which is also used for depletion. I
Autor:
Ashley M. Toye, Alexander J Howie, W. J. Mawby, Fiona E. Karet, Moin A. Saleem, Dalila Hallouane, Alice C. N. Brown
Publikováno v:
American Journal of Physiology-Renal Physiology
Rhesus glycoprotein homologs RhAG, RhBG, and RhCG comprise a recently identified branch of the Mep/Amt ammonia transporter family. Animal studies have shown that RhBG and RhCG are present in the kidney distal tubules. Studies in mouse and rat tissue