Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alice Borella"'
Publikováno v:
Brain Research. 1189:203-214
Prior research has reliably found high blood (hyperserotonemia) - but low brain - serotonin levels in autistic individuals. At early stages of development, high levels of serotonin in the blood may enter the brain of a developing fetus, causing a los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ececc716f76c155f2099aaade1b71362
https://doi.org/10.1016/j.brainres.2007.10.063
https://doi.org/10.1016/j.brainres.2007.10.063
Publikováno v:
Behavioural Brain Research. 141:229-236
S-100 beta, a gene triplicated in Down Syndrome (DS), is thought to play a role in development of the brain in general, and in the serotonergic neuronal system in particular. We have been studying an animal model of DS, based on overexpression of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0d08aabbb78a2509192319f2e9a128
https://doi.org/10.1016/s0166-4328(02)00373-x
https://doi.org/10.1016/s0166-4328(02)00373-x
Transient expression of S-100β immunostaining in developing thalamus and somatosensory cortex of rat
Publikováno v:
Developmental Brain Research. 142:101-104
Serotonin is thought to affect the development of barrel fields in somatosensory cortex of rat and transient expression of the serotonin transporter has been reported in relevant thalamic (ventral posterior) and cortical (layer IV of parietal) region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3028bdaaf4964500d365d865806fd7f
https://doi.org/10.1016/s0165-3806(03)00012-9
https://doi.org/10.1016/s0165-3806(03)00012-9
Autor:
Lee A. Shapiro, Alice Borella, Wei Huang, Fabian Johnstone, Alina Tudorica, Patricia M. Whitaker-Azmitia, David Kahne
Publikováno v:
Physiology & Behavior. 75:403-410
Autism is classified as a pervasive developmental disorder, with several cardinal features including sensory disturbances, obsessive-compulsive-like behavior, lack of bonding to caregivers and motor disturbances. To date, there is a lack of an animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa88562be391df233ae171f6a02e46a
https://doi.org/10.1016/s0031-9384(01)00673-4
https://doi.org/10.1016/s0031-9384(01)00673-4
Autor:
Alice Borella, Carrie Mazer, Kenneth Taheny, Patricia M. Whitaker-Azmitia, Jennifer Muneyyirci, Nicholas Raio
Publikováno v:
Brain Research. 760:68-73
Studies in the past have revealed serotonin to play a role in regulating the development and maturation of the mammalian brain, largely through the release of the astroglial protein S-100beta. S-100beta plays a role in neurite extension, microtubule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36c588f9cdf21ab13842bce88be9a39
https://doi.org/10.1016/s0006-8993(97)00297-7
https://doi.org/10.1016/s0006-8993(97)00297-7
Publikováno v:
Neuropsychopharmacology. 12:269-272
Many trophic factors are now thought to also function in maintenance of the adult brain. We hypothesized that since serotonin plays a role in synaptogenesis, it may also function in maintenance of synapses in the adult. Adult rats were depleted of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91ca6c683b96636fa662d76f5567307
https://doi.org/10.1016/0893-133x(94)00081-a
https://doi.org/10.1016/0893-133x(94)00081-a
Publikováno v:
Brain research. 877(2)
Learning and memory are often correlated with cellular changes within the hippocampus, and drugs or environmental factors which affect learning and memory will thus often induce observable morphological changes in this structure. Like tetrahydrocanna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46a81aee01a7647a46654508df4c42e
https://pubmed.ncbi.nlm.nih.gov/10986361
https://pubmed.ncbi.nlm.nih.gov/10986361
Autor:
Michael Wingate, John C. Roder, Robert Gerlai, Patricia M. Whitaker-Azmitia, Alice Borella, Efrain C. Azmitia
Publikováno v:
Brain research. 776(1-2)
S-100 beta is a neurotrophic factor released by astroglial cells and localized to chromosome 21, within the region which is considered obligate for Down's syndrome (DS). S-100 beta is increased in the postmortem brains of both DS and Alzheimer's dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72479b1e63b69596b17ade929d6fca8a
https://pubmed.ncbi.nlm.nih.gov/9439795
https://pubmed.ncbi.nlm.nih.gov/9439795
Publikováno v:
European journal of pharmacology. 275(2)
The use of high doses of cisplatin in treating cancers has been limited by two major adverse effects--emesis and peripheral neuropathies. The emesis has become largely controlled by the introduction of a new class of drugs--the 5-HT3 receptor antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342f4cb8ef676f6279b8bc97e63762a1
https://pubmed.ncbi.nlm.nih.gov/7796848
https://pubmed.ncbi.nlm.nih.gov/7796848