Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alice Bittar"'
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The multifactorial and complex nature of Alzheimer's disease (AD) has made it difficult to identify therapeutic targets that are causally involved in the disease process. However, accumulating evidence from experimental and clinical studies that inve
Externí odkaz:
https://doaj.org/article/14de4fd35ac84c58a8cc989888c3172a
Autor:
Alice Bittar, Rabab Al-Lahham, Nemil Bhatt, Kenya Moore, Mauro Montalbano, Cynthia Jerez, Leiana Fung, Salome McAllen, Anna Ellsworth, Rakez Kayed
Publikováno v:
Journal of Alzheimer's Disease. 90:1103-1122
Background: Tau oligomers are one of the most toxic species, displaying prion-like strains which have different conformations resulting in different tauopathies. Passive immunotherapy targeting different tau species is a promising therapeutic approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b48476c529581443aed134e1f97643
https://doi.org/10.3233/jad-220518
https://doi.org/10.3233/jad-220518
Autor:
Mauro Montalbano, Leiana Fung, Nemil Bhatt, Sagar Gaikwad, Alice Bittar, Nicha Puangmalai, Urmi Sengupta, Rakez Kayed
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7389ba5f88cc0551e9ccfe18bf0c42
https://doi.org/10.1002/alz.062374
https://doi.org/10.1002/alz.062374
Autor:
Alice Bittar, Stephanie Garcia, Rakez Kayed, Urmi Sengupta, Nicha Puangmalai, Mauro Montalbano, Sagar Gaikwad, Nemil Bhatt, Salome McAllen, Minal Sonawane
Publikováno v:
Cell reports
SUMMARY Aging, pathological tau oligomers (TauO), and chronic inflammation in the brain play a central role in tauopathies, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). However, the underlying mechanism of TauO-induced agin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0aaea688af9f08710dab72dca5c854d
https://pubmed.ncbi.nlm.nih.gov/34289368
https://pubmed.ncbi.nlm.nih.gov/34289368
Autor:
Salome McAllen, Urmi Sengupta, Mauro Montalbano, Sagar Gaikwad, Rakez Kayed, Nemil Bhatt, Stephanie Garcia, Nicha Puangmalai, Alice Bittar
Publikováno v:
SSRN Electronic Journal.
Aging, pathological tau oligomers (TauO) and chronic inflammation in the brain play a central role in tauopathies, including Alzheimer's disease (AD) and frontotemporal dementia (FTD). However, the underlying mechanism of TauO-induced aging-related n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a50ce6435edbc1f811f33640673d208
https://doi.org/10.2139/ssrn.3753798
https://doi.org/10.2139/ssrn.3753798
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
NPJ Vaccines
NPJ Vaccines
With increasing age, as the incidence of Alzheimer’s disease is increasing, finding a therapeutic intervention is becoming critically important to either prevent or slow down the progression of the disease. Passive immunotherapy has been demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670a0c81ba552d51135e27231a89527f
http://link.springer.com/article/10.1038/s41541-018-0046-8
http://link.springer.com/article/10.1038/s41541-018-0046-8
Publikováno v:
Neurobiology of disease
Neurobiology of Disease, Vol 134, Iss, Pp-(2020)
Neurobiology of Disease, Vol 134, Iss, Pp-(2020)
The multifactorial and complex nature of Alzheimer’s disease (AD) has made it difficult to identify therapeutic targets that are causally involved in the disease process. However, accumulating evidence from experimental and clinical studies that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fed528373fe581745ad61985dec9b78
https://pubmed.ncbi.nlm.nih.gov/31841678
https://pubmed.ncbi.nlm.nih.gov/31841678
Autor:
Mauro Montalbano, Rakez Kayed, Charles L. Rosen, Brandon Lucke-Wold, Tasneem F. Hasan, Nicha Puangmalai, Alice Bittar, Giulio Taglialatela, Mariana Carretero Murillo, Nemil Bhatt, Ryan C. Turner, Salome McAllen, Aric F. Logsdon, Anna Ellsworth
Publikováno v:
Brain Communications
Soluble tau aggregates have been highlighted in mTBI-induced cellular dysfunction and neurodegeneration. We used an established mTBI model to investigate differences between tau oligomers isolated after single vs. repetitive mTBI. Single and repeated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80a33631077111f0b7044fe8f42f292
http://europepmc.org/articles/PMC6777515
http://europepmc.org/articles/PMC6777515
Autor:
Mariana Carretero-Murillo, Tasneem Hassan, Anna Ellsworth, Rakez Kayed, Alice Bittar, Salome McAllen, Nemil Bhatt
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45bbe7598f49384d78eb05ce4c94d36
https://doi.org/10.1016/j.jalz.2018.06.022
https://doi.org/10.1016/j.jalz.2018.06.022