Výsledky vyhledávání - "Alice Barbarin"

Akademický článek

Early activation and recruitment of invariant natural killer T cells during liver ischemia-reperfusion: the major role of the alarmin interleukin-33

Autor: Aurélie Robin, Claire Mackowiak, Romain Bost, Fanny Dujardin, Alice Barbarin, Antoine Thierry, Thierry Hauet, Luc Pellerin, Jean-Marc Gombert, Ephrem Salamé, André Herbelin, Louise Barbier

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Over the past thirty years, the complexity of the αβ-T cell compartment has been enriched by the identification of innate-like T cells (ITCs), which are composed mainly of invariant natural killer T (iNKT) cells and mucosal-associated invariant T (

Externí odkaz: https://doaj.org/article/4a8c202f2f744087ab161fad70102311

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Akademický článek

Innate T-αβ lymphocytes as new immunological components of anti-tumoral 'off-target' effects of the tyrosine kinase inhibitor dasatinib

Autor: Alice Barbarin, Myriam Abdallah, Lucie Lefèvre, Nathalie Piccirilli, Emilie Cayssials, Lydia Roy, Jean-Marc Gombert, André Herbelin

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

Abstract Kinase inhibitors hold great potential as targeted therapy against malignant cells. Among them, the tyrosine kinase inhibitor dasatinib is known for a number of clinically relevant off-target actions, attributed in part to effects on compone

Externí odkaz: https://doaj.org/article/93d95eabd8174e51acc184d4b1943df3

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Akademický článek

Allotransplantation Is Associated With Exacerbation of CD8 T-Cell Senescence: The Particular Place of the Innate CD8 T-Cell Component

Autor: Lauren Daniel, Marion Tassery, Clara Lateur, Antoine Thierry, André Herbelin, Jean-Marc Gombert, Alice Barbarin

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Immunosenescence is a physiological process that is associated with changes in the immune system, particularly among CD8 T-cells. Recent studies have hypothesized that senescent CD8 T-cells are produced with chronologic age by chronic stimulation, le

Externí odkaz: https://doaj.org/article/dc98233988894258aa6db86be27698d5

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Akademický článek

Interleukin-1 Family Cytokines: Keystones in Liver Inflammatory Diseases

Autor: Louise Barbier, Maroua Ferhat, Ephrem Salamé, Aurélie Robin, André Herbelin, Jean-Marc Gombert, Christine Silvain, Alice Barbarin

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

The pyrogenic property being the first activity described, members of the interleukin-1 superfamily (IL-1α, IL-1β, IL-18, and the newest members: IL-33, IL-36, IL-37, and IL-38) are now known to be involved in several inflammatory diseases such as

Externí odkaz: https://doaj.org/article/6a4f092cbaf544f8a37d0b6253d79890

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Akademický článek

The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33

Autor: Maroua Haroun Ferhat, Aurélie Robin, Louise Barbier, Antoine Thierry, Jean-Marc Gombert, Alice Barbarin, André Herbelin

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Although the contribution of iNKT cells to induction of sterile inflammation is now well-established, the nature of the endogenous compounds released early after cellular stress or damage that drive their activation and recruitment remains poorly und

Externí odkaz: https://doaj.org/article/e33979354b0d448f9c02957def36ab1a

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Akademický článek

Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression.

Autor: Mahmoud El Maassarani, Alice Barbarin, Gaëlle Fromont, Ouafae Kaissi, Margot Lebbe, Brigitte Vannier, Ahmed Moussa, Paule Séité

Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0155950 (2016)

The EGF-family of tyrosine-kinase receptors activates cytoplasmic pathways involved in cell proliferation, migration and differentiation in response to specific extracellular ligands. Beside these canonical pathways, the nuclear localization of the E

Externí odkaz: https://doaj.org/article/9019e2f0a9a546feb177666a693500ce

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Akademický článek

Human papillomavirus 16 oncoprotein E7 stimulates UBF1-mediated rDNA gene transcription, inhibiting a p53-independent activity of p14ARF.

Autor: Isabelle Dichamp, Paule Séité, Gérard Agius, Alice Barbarin, Agnès Beby-Defaux

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96136 (2014)

High-risk human papillomavirus oncoproteins E6 and E7 play a major role in HPV-related cancers. One of the main functions of E7 is the degradation of pRb, while E6 promotes the degradation of p53, inactivating the p14ARF-p53 pathway. pRb and p14ARF c

Externí odkaz: https://doaj.org/article/c87fda61cd6d4254b472394075dd4ad0

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Virtual Memory CD8+ T Cells: Origin and Beyond

Autor: Maria Estefania Viano, Natalia Soledad Baez, Constanza Savid-Frontera, Nicolás Leonel Lidon, Deborah L. Hodge, André Herbelin, Jean-Marc Gombert, Alice Barbarin, Maria Cecilia Rodriguez-Galan

Publikováno v: Journal of Interferon and Cytokine Research
Journal of Interferon and Cytokine Research, Mary Ann Liebert, 2022, Online ahead of print. ⟨10.1089/jir.2022.0053⟩

International audience; The presence of CD8+ T cells with a memory phenotype in nonimmunized mice has been noted for decades, but it was not until about 2 decades ago that they began to be studied in greater depth. Currently called virtual memory CD8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d593f3452306523900a089afdaaf95
https://doi.org/10.1089/jir.2022.0053

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