Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alice Ballone"'
Autor:
Madita Wolter, Domenico Lentini Santo, Petr Herman, Alice Ballone, Federica Centorrino, Tomas Obsil, Christian Ottmann
Publikováno v:
ACS Omega, Vol 5, Iss 10, Pp 5380-5388 (2020)
Externí odkaz:
https://doaj.org/article/3f60aa15343f4c3abd9da326b2617fb0
Publikováno v:
Data in Brief, Vol 19, Iss , Pp 1683-1687 (2018)
Activation of Ras-MAPK signaling regulates essential cellular functions; its aberration leads to irregular cell proliferation and differentiation (i.e. pancreatic cancer). Previously, it was revealed that the formation of the complex of the 14-3-3 pr
Externí odkaz:
https://doaj.org/article/0b7dffb9d9bd4129b7a408eba9a58aa4
Publikováno v:
Molecules, Vol 23, Iss 6, p 1386 (2018)
In recent years, targeting the complex network of protein–protein interactions (PPIs) has been identified as a promising drug-discovery approach to develop new therapeutic strategies. 14-3-3 is a family of eukaryotic conserved regulatory proteins w
Externí odkaz:
https://doaj.org/article/bac902d953ec427bbacf2dc87b7bd4e0
Autor:
Christian Ottmann, Christine E. Prosser, Alice Ballone, Francesca Picarazzi, Mattia Mori, Jeremy Martin Davis
Publikováno v:
Journal of Chemical Information and Modeling, 60(12). American Chemical Society
The exploration of the druggability of certain protein-protein interactions (PPIs) still remains a challenging task in drug discovery. Here, we present a case study using the 14-3-3-PPI, showing how small molecules can be located that are able to mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb0cb464e91f1c0f188b40a060f4ec3
https://doi.org/10.1021/acs.jcim.0c00722
https://doi.org/10.1021/acs.jcim.0c00722
Autor:
M. Wolter, Tomas Obsil, Petr Herman, Federica Centorrino, Domenico Lentini Santo, Alice Ballone, Christian Ottmann
Publikováno v:
ACS Omega
ACS omega 5(10), 5380-5388 (2020). doi:10.1021/acsomega.9b04413
ACS Omega, Vol 5, Iss 10, Pp 5380-5388 (2020)
ACS Omega, 5(10), 5380-5388. American Chemical Society
ACS omega 5(10), 5380-5388 (2020). doi:10.1021/acsomega.9b04413
ACS Omega, Vol 5, Iss 10, Pp 5380-5388 (2020)
ACS Omega, 5(10), 5380-5388. American Chemical Society
Inflammatory responses mediated by the transcription factor nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB) play key roles in immunity, autoimmune diseases, and cancer. NF-κB is directly regulated through protein-protein inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ec34543aaf0a6eea9169bae4da0b33
http://europepmc.org/articles/PMC7081424
http://europepmc.org/articles/PMC7081424
Autor:
Alice, Ballone, Francesca, Picarazzi, Christine, Prosser, Jeremy, Davis, Christian, Ottmann, Mattia, Mori
Publikováno v:
Journal of chemical information and modeling. 60(12)
The exploration of the druggability of certain protein-protein interactions (PPIs) still remains a challenging task in drug discovery. Here, we present a case study using the 14-3-3-PPI, showing how small molecules can be located that are able to mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19356cc9a7cf32c981b897cc66291908
https://pubmed.ncbi.nlm.nih.gov/33138374
https://pubmed.ncbi.nlm.nih.gov/33138374
Autor:
Beatrice Dufrusine, Sergio Oddi, Gianni De Fabritiis, Filomena Fezza, Mauro Maccarrone, Monica Simonetti, Annalaura Sabatucci, Clotilde B. Angelucci, Enrico Dainese, Alice Ballone
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9646d9d64f2430fb4a6efc14ca337b5
Autor:
Markus Kilisch, Sergiy Tokar, Henning Urlaub, Julia Menzel, Christof Lenz, Kirsten Unthan-Fechner, Daniel Kownatzki-Danger, Stephan E. Lehnart, Alice Ballone, Blanche Schwappach, Mattia Mori, Michael J. Shattock, Christian Ottmann
Publikováno v:
Science Signaling, 13(647):eaaz1436. American Association for the Advancement of Science (AAAS)
The cardiac membrane protein phospholamban (PLN) is targeted by protein kinase A (PKA) at Ser16 and by Ca2+/calmodulin-dependent protein kinase II (CaMKII) at Thr17 β-Adrenergic stimulation and PKA-dependent phosphorylation of Ser16 acutely stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d49816aaf3db203a0ef5bdd8c433d5
http://hdl.handle.net/11365/1120352
http://hdl.handle.net/11365/1120352
Autor:
Filomena Fezza, Monica Simonetti, Sergio Oddi, Mauro Maccarrone, Clotilde B. Angelucci, Alice Ballone, Beatrice Dufrusine, Annalaura Sabatucci, Enrico Dainese, Gianni De Fabritiis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports
Scientific Reports
Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd22bb456716d6c10ab3b685d359600d
http://link.springer.com/article/10.1038/s41598-020-62514-w
http://link.springer.com/article/10.1038/s41598-020-62514-w
Publikováno v:
FEBS Letters, 592(7), 1211-1220. Elsevier
FEBS Letters
FEBS Letters
The ubiquitin-specific protease 8 (USP8)/14-3-3 protein-protein interaction has recently been shown to exert a significant role in the pathogenesis of Cushing's disease (CD). USP8 is a deubiquitinase that prevents epidermal growth factor receptor (EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090cf01f6855827e429f667d3e82f96a
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85042642490
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85042642490