Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alice A. N. Marriott"'
Autor:
Rose E Jeeves, Alice A N Marriott, Steven T Pullan, Kim A Hatch, Jon C Allnutt, Irene Freire-Martin, Charlotte L Hendon-Dunn, Robert Watson, Adam A Witney, Richard H Tyler, Catherine Arnold, Philip D Marsh, Timothy D McHugh, Joanna Bacon
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bac
Externí odkaz:
https://doaj.org/article/b77774f4b89f45aa86fd10187fd3db40
Autor:
Jon C. Allnutt, Joanna Bacon, Charlotte L. Hendon-Dunn, Alice A. N. Marriott, Henry Pertinez, Kim A. Hatch, Geraint Davies
Publikováno v:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Modulation of growth rate in Mycobacterium tuberculosis is key to its survival in the host; particularly with regard to its adaptation during chronic infection when the growth rate is very slow. The resulting physiological changes will influence the
Autor:
Charlotte L, Hendon-Dunn, Henry, Pertinez, Alice A N, Marriott, Kim, Hatch, Jon C, Allnutt, Geraint, Davies, Joanna, Bacon
Publikováno v:
Antimicrobial Agents and Chemotherapy
Modulation of the growth rate in Mycobacterium tuberculosis is key to its survival in the host, particularly with regard to its adaptation during chronic infection, when the growth rate is very slow. The resulting physiological changes influence the
Autor:
Stephen Thomas, Graham Bottley, Kim A. Hatch, Philip Marsh, Joanna Bacon, Robert J. Watson, Stephen Taylor, Jonathan Charles Allnutt, Kathryn Doris, Charlotte L. Hendon-Dunn, Alice A. N. Marriott
Publikováno v:
Antimicrobial Agents and Chemotherapy
Current methods for assessing the drug susceptibility of Mycobacterium tuberculosis are lengthy and do not capture information about viable organisms that are not immediately culturable under standard laboratory conditions as a result of antibiotic e
Autor:
Andrew White, Sally Sharpe, Laura Sibley, Philip Marsh, Mike Dennis, Alice A. N. Marriott, Ann Williams
Publikováno v:
Cells, Vol 1, Iss 1, Pp 5-14 (2012)
Cells
Volume 1
Issue 1
Pages 5-14
Cells
Volume 1
Issue 1
Pages 5-14
Tuberculosis is a global health problem. The Mycobacterium bovis Bacille Calmette Guerin (BCG) vaccine has variable efficacy (0-80%) so there is a drive to develop novel vaccines. The cytokine, interferon gamma (IFNγ), is an essential component of t
Autor:
Andrew White, Helen McShane, Adrian V. S. Hill, A. McIntyre, Simon O. Clark, Fergus V. Gleeson, Karen E. Gooch, Sally Sharpe, E. Nuth, Alice A. N. Marriott, Graham Hall, Philip Marsh, Ann Williams, Stuart D. Dowall, Natalie E. R. Beveridge, Mike Dennis, Randall J. Basaraba
Publikováno v:
Clinical and vaccine immunology : CVI. 17(8)
The establishment of an aerosol challenge model in nonhuman primates (NHPs) for the testing of vaccines against Mycobacterium tuberculosis would assist the global effort to optimize novel vaccination strategies. The endpoints used in preclinical chal
Autor:
Adam A. Witney, Timothy D. McHugh, Rose E. Jeeves, Kim A. Hatch, Richard H. Tyler, Philip Marsh, Robert J. Watson, Steven T. Pullan, Charlotte L. Hendon-Dunn, Irene Freire-Martin, Jon C. Allnutt, Alice A. N. Marriott, Joanna Bacon, Catherine Arnold
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bac
Autor:
Graham Hall, Simon Clark, Jon Allnutt, Robert J. Watson, Alice A. N. Marriott, Joanna Bacon, Gurdyal S. Besra, Geoff Pearson, Evelina Gabasova, Lorenz Wernisch, Emma Rayner, Kim A. Hatch, Rose E. Jeeves, Philip Marsh, Ann Williams, Howard Tolley, Luke J. Alderwick
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e87329 (2014)
PLoS ONE, Vol 9, Iss 2, p e87329 (2014)
A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental cond