Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alice A Royal"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186293 (2017)
The slow delayed-rectifier potassium current (IKs) is crucial for human cardiac action potential repolarization. The formation of IKs requires co-assembly of the KCNQ1 α-subunit and KCNE1 β-subunit, and mutations in either of these subunits can lea
Externí odkaz:
https://doaj.org/article/26b7a68a8ca7449184426f2c2a4853a7
Publikováno v:
EP Europace. 23
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): British Heart Foundation Phosphatidylinositol-4,5-biphosphate (PIP2) is implicated in the regulation and modulation of the IKS channel
Autor:
Qadeer Aziz, Stephen C Harmer, Vrijraj Sinhji H.S. Rathod, Pier D. Lambiase, Andrew Tinker, Alice A Royal
Publikováno v:
Heart Rhythm. 18:S101
Autor:
Stephen C Harmer, William J. McKenna, Pier D. Lambiase, Andrew Tinker, Jagdeep S. Mohal, Alice A Royal
Publikováno v:
The Biochemical journal. 462(1)
The KCNQ1 (potassium voltage-gated channel, KQT-like subfamily, member 1) gene encodes the Kv7.1 potassium channel which forms a complex with KCNE1 (potassium voltage-gated channel Isk-related family member 1) in the human heart to produce the repola