Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alice, Wiedeman"'
Autor:
Erin M. Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, Vivian H. Gersuk, Bryce Fuchs, S. Alice Long, Peter S. Linsley
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins and relationships between the
Externí odkaz:
https://doaj.org/article/8d3fb1a37da44494b3b4cd1c67e7d55e
Autor:
Eric D. Morrell, Pavan K. Bhatraju, Neha A. Sathe, Jonathan Lawson, Linzee Mabrey, Sarah E. Holton, Scott R. Presnell, Alice Wiedeman, Carolina Acosta-Vega, Mallorie A. Mitchem, Ted Liu, Xin-Ya Chai, Sharon Sahi, Carolyn Brager, Marika Orlov, Sana S. Sakr, Anthony Sader, Dawn M. Lum, Neall Koetje, Ashley Garay, Elizabeth Barnes, Gail Cromer, Mary K. Bray, Sudhakar Pipavath, Susan L. Fink, Laura Evans, S. Alice Long, T. Eoin West, Mark M. Wurfel, Carmen Mikacenic
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(1)
Critically ill patients manifest many of the same immune features seen in coronavirus disease 2019 (COVID-19), including both “cytokine storm” and “immune suppression.” However, direct comparisons of molecular and cellular profiles between co
Autor:
Javad, Rasouli, Giacomo, Casella, Satoshi, Yoshimura, Weifeng, Zhang, Dan, Xiao, James, Garifallou, Michael V, Gonzalez, Alice, Wiedeman, Anna, Kus, Elisabeth R, Mari, Paolo, Fortina, Hakon, Hakonarson, S Alice, Long, Guang-Xian, Zhang, Bogoljub, Ciric, Abdolmohamad, Rostami
Publikováno v:
Science immunology. 5(52)
Elevation of granulocyte-macrophage colony-stimulating factor (GM-CSF)–producing T helper (T
Autor:
Carolina Acosta-Vega, David Skibinski, Anna Kus, Cate Speak, Alice Long, Uma Malhotra, Jane H Buckner, Alice Wiedeman
Publikováno v:
The Journal of Immunology. 206:62.13-62.13
During the Coronavirus Disease 2019 (COVID-19) outbreak, a robust and consistent strategy was required for assessing the immune landscape. Our rapid research response to COVID-19 was enabled by use of standardized assays. The assays included a 33-mar
Autor:
Javad Rasouli, Giacomo Casella, Satoshi Yoshimura, Weifeng Zhang, Dan Xiao, Gaurav Kumar, James Garifallou, Michael V. Gonzalez, Alice Wiedeman, Elisabeth R. Mari, Hsin-Yao Tang, Paolo Fortina, Hakon Hakonarson, Alice Long, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
SSRN Electronic Journal.
Using single-cell RNA-seq and high-dimensional single-cell mass cytometry (CyTOF), we identified eight distinct populations of antigen-experienced CD45RA-CD4+ T cells in peripheral blood of healthy donors. In addition to Tregs and established Th line
Publikováno v:
The Journal of Immunology. 204:142.34-142.34
CD8 T Cell exhaustion is associated with poor clinical outcome in cancer and chronic infection, but positive outcome in autoimmunity. Recently, phenotypic and functional heterogeneity within exhausted CD8 T cells suggests lineage subsets. We observed
Publikováno v:
The Journal of Immunology. 182:86.13-86.13
Immune dysregulation in children due to primary immunodeficiency, autoimmune disease or immunomosuppressive therapy may be characterized in detail by multiparametric flow cytometry. To determine age-dependent reference values for healthy children, we
Publikováno v:
The Journal of Immunology. 182:99.15-99.15
PD-L1 is an inhibitory protein expressed on monocytes (Mo) to maintain peripheral T cell tolerance. We previously reported deficient expression of PD-L1 on Mo from patients with active SLE. To investigate the mechanisms for dysregulated PD-L1 express